Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Arturo J, Vegas"'
Publikováno v:
Bioconjugate chemistry. 33(7)
The indiscriminate biodistribution of therapeutics can be a key barrier to their safety and efficacy. Localization of compounds into non-diseased tissues often leads to both toxic and dose-limiting effects. To overcome this barrier, nanomedicine impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845e3bad1e631236e4ed389fbc0367b1
https://pubmed.ncbi.nlm.nih.gov/35758018
https://pubmed.ncbi.nlm.nih.gov/35758018
Autor:
Stephen T Nestor, Daniel Sheehy, Arturo J. Vegas, Angela N. Koehler, Kelly Tan, Sean P. Quinnell, Shelby K. Doyle, Becky S Leifer, Luke M. Ceo
Publikováno v:
ACS Chemical Biology. 15:2649-2654
Interleukin-4 (IL-4) is a multifunctional cytokine and an important regulator of inflammation. When deregulated, IL-4 activity is associated with asthma, allergic inflammation, and multiple types of cancer. While antibody-based inhibitors targeting t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5aff60a227e0e1100881fd074c1e9a
https://doi.org/10.1021/acschembio.0c00615
https://doi.org/10.1021/acschembio.0c00615
Publikováno v:
Nano Lett
Structured nanoassemblies are biomimetic structures that are enabling applications from nanomedicine to catalysis(5–7). One approach to achieve these spatially-organized architectures is utilizing amphiphilic diblock copolymers with one or two macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ec9a7e130dbf4000ff76ad43896266
https://europepmc.org/articles/PMC8768502/
https://europepmc.org/articles/PMC8768502/
Autor:
Omid Veiseh, Arturo J. Vegas
Publikováno v:
Adv Drug Deliv Rev
The foreign body response is an immunological process that leads to the rejection of implanted devices and presents a fundamental challenge to their performance, durability, and therapeutic utility. Recent advances in materials development and device
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d48841bdf0dc9e9801aafffd51486f
https://doi.org/10.1016/j.addr.2019.08.010
https://doi.org/10.1016/j.addr.2019.08.010
Autor:
Matthew J. Webber, Omid Veiseh, Marissa Griffin, Shady Farah, Jose Oberholzer, Arturo J. Vegas, Hok Hei Tam, Daniel G. Anderson, Andrew Bader, Jie Li, Alan Chiu, Robert Langer, Sean M. Siebert, Joshua C. Doloff, Dale L. Greiner, Erin Langan, Michael Chen, Raj Thakrar, Meirigeng Qi, Siddharth Jhunjhunwala, Katherine Tang, Nimit Dholokia, Atieh Sadraei, Minglin Ma, Stephanie Aresta-Dasilva
Publikováno v:
Nature materials
Host recognition and immune-mediated foreign body response to biomaterials can compromise the performance of implanted medical devices. To identify key cell and cytokine targets, here we perform in-depth systems analysis of innate and adaptive immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8084ab86bbfc68597cecda40c07b888
https://doi.org/10.1038/nmat4866
https://doi.org/10.1038/nmat4866
Autor:
Jose Oberholzer, Daniel G. Anderson, Douglas Isa, Bo-Ru Yang, Hui jiuan Chen, Hok Hei Tam, Ira Joshi, Volkan Yesilyurt, Arturo J. Vegas, Jun Tao, Joshua C. Doloff, Weiheng Wang, Jie Li, Xi Xie, Sofia Ghani, Mustafa Omami, Andrew Bader, Robert Langer, Shady Farah, Omid Veiseh, James J. McGarrigle, Katrina Ann Williamson, Atieh Sadraei
Publikováno v:
Nature biomedical engineering
Continuous glucose monitors (CGMs), used by patients with diabetes mellitus, can autonomously track fluctuations in blood glucose over time. However, the signal produced by CGMs during the initial recording period following sensor implantation contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdec704f4c91f1182ad4c77013d844c
https://pubmed.ncbi.nlm.nih.gov/31015726
https://pubmed.ncbi.nlm.nih.gov/31015726
Autor:
Matthew A, Bochenek, Omid, Veiseh, Arturo J, Vegas, James J, McGarrigle, Meirigeng, Qi, Enza, Marchese, Mustafa, Omami, Joshua C, Doloff, Joshua, Mendoza-Elias, Mohammad, Nourmohammadzadeh, Arshad, Khan, Chun-Chieh, Yeh, Yuan, Xing, Douglas, Isa, Sofia, Ghani, Jie, Li, Casey, Landry, Andrew R, Bader, Karsten, Olejnik, Michael, Chen, Jennifer, Hollister-Lock, Yong, Wang, Dale L, Greiner, Gordon C, Weir, Berit Løkensgard, Strand, Anne Mari A, Rokstad, Igor, Lacik, Robert, Langer, Daniel G, Anderson, Jose, Oberholzer
Publikováno v:
Nature biomedical engineering. 2(11)
The transplantation of pancreatic islet cells could restore glycaemic control in patients with type-I diabetes. Microspheres for islet encapsulation have enabled long-term glycaemic control in diabetic rodent models; yet human patients transplanted w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4470d20223a3b29412cc400e9297024
https://pubmed.ncbi.nlm.nih.gov/31015616
https://pubmed.ncbi.nlm.nih.gov/31015616
The clinical onset of type 1 diabetes is characterized by the destruction of the insulin-producing β cells of the pancreas, and is caused by autoantigen-induced inflammation (insulitis) of the islets of Langerhans. The current standard of care for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf837c851b32d12c7f4ed9078690ee75
https://europepmc.org/articles/PMC6774349/
https://europepmc.org/articles/PMC6774349/
Autor:
Minglin Ma, Jose Oberholzer, Dale L. Greiner, Arturo J. Vegas, Nimit Dholakia, Michael Chen, Omid Veiseh, Raj Thakrar, Siddharth Jhunjhunwala, Stephanie Aresta-Dasilva, Jie Li, Alan Chiu, Sean M. Siebert, Katherine Tang, Andrew Bader, Robert Langer, Meirigeng Qi, Hok Hei Tam, Daniel G. Anderson, Atieh Sadraei, Erin Langan, Joshua C. Doloff, Marissa Griffin, Shady Farah, Matthew J. Webber
Publikováno v:
Nature Materials. 20:1038-1038
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e99b0d92ebe2c345a7b81d9819995969
https://doi.org/10.1038/s41563-021-01023-1
https://doi.org/10.1038/s41563-021-01023-1
Autor:
Rosemary L. Kanasty, Arturo J. Vegas, Luke M. Ceo, Martin Maier, Klaus Charisse, Jayaprakash K. Nair, Robert Langer, Daniel G. Anderson
Publikováno v:
Angewandte Chemie. 128:9681-9685
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f0afc0e5c87be430dcb6ee782b612ac
https://doi.org/10.1002/ange.201602748
https://doi.org/10.1002/ange.201602748