Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Arturo, Zazpe"'
1
Akademický článek
The Synthetic Flavonoid Hidrosmin Improves Endothelial Dysfunction and Atherosclerotic Lesions in Diabetic Mice
Autor: Luna Jiménez-Castilla, Lucas Opazo-Ríos, Gema Marin-Royo, Macarena Orejudo, Raquel Rodrigues-Diez, Constanza Ballesteros-Martínez, Manuel Soto-Catalán, Teresa Caro-Ordieres, Inés Artaiz, Tatiana Suarez-Cortés, Arturo Zazpe, Gonzalo Hernández, Marcelino Cortés, José Tuñón, Ana M. Briones, Jesús Egido, Carmen Gómez-Guerrero
Publikováno v: Antioxidants, Vol 11, Iss 12, p 2499 (2022)
In diabetes, chronic hyperglycemia, dyslipidemia, inflammation and oxidative stress contribute to the progression of macro/microvascular complications. Recently, benefits of the use of flavonoids in these conditions have been established. This study
Externí odkaz: https://doaj.org/article/f21f58fee26c4c3f8fd39993ac6c03df
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3
Akademický článek
Nephroprotective Effects of Synthetic Flavonoid Hidrosmin in Experimental Diabetic Nephropathy
Autor: Luna Jiménez-Castilla, Gema Marín-Royo, Macarena Orejudo, Lucas Opazo-Ríos, Teresa Caro-Ordieres, Inés Artaiz, Tatiana Suárez-Cortés, Arturo Zazpe, Gonzalo Hernández, Carmen Gómez-Guerrero, Jesús Egido
Publikováno v: Antioxidants, Vol 10, Iss 12, p 1920 (2021)
Diabetes mellitus (DM) is a high-impact disease commonly characterized by hyperglycemia, inflammation, and oxidative stress. Diabetic nephropathy (DN) is a common diabetic microvascular complication and the leading cause of chronic kidney disease wor
Externí odkaz: https://doaj.org/article/8faba0f8461544b8928ab6ca5eee94c3
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4
Akademický článek
Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells
Autor: Marina Mojena, Adrián Povo-Retana, Silvia González-Ramos, Victoria Fernández-García, Javier Regadera, Arturo Zazpe, Inés Artaiz, Paloma Martín-Sanz, Francisco Ledo, Lisardo Boscá
Publikováno v: Frontiers in Oncology, Vol 8 (2018)
Melanomas are heterogeneous and aggressive tumors, and one of the worse in prognosis. Melanoma subtypes follow distinct pathways until terminal oncogenic transformation. Here, we have evaluated a series of molecules that exhibit potent cytotoxic effe
Externí odkaz: https://doaj.org/article/00f532f70f4249eaa1322bb45a89dce0
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6
Nephroprotective Effects of Synthetic Flavonoid Hidrosmin in Experimental Diabetic Nephropathy
Autor: Gonzalo Hernández, Inés Artaiz, Carmen Gomez-Guerrero, Jesús Egido, Tatiana Suárez-Cortés, Lucas Opazo-Ríos, Macarena Orejudo, Arturo Zazpe, Teresa Caro-Ordieres, Gema Marín-Royo, Luna Jimenez-Castilla
Publikováno v: Antioxidants; Volume 10; Issue 12; Pages: 1920
Antioxidants, Vol 10, Iss 1920, p 1920 (2021)
Antioxidants
Biblos-e Archivo. Repositorio Institucional de la UAM
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Diabetes mellitus (DM) is a high‐impact disease commonly characterized by hyperglycemia, inflammation, and oxidative stress. Diabetic nephropathy (DN) is a common diabetic microvascular complication and the leading cause of chronic kidney disease w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f212e5736fd6a69011792216f2ab51
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7
In vitro and in vivo characterization of F-97013-GD, a partial 5-HT1A agonist with antipsychotic- and antiparkinsonian-like properties
Autor: Ana Innerárity, Angel Pazos, Elena del Olmo, Luis Labeaga, Inés Artaiz, Aurelio Orjales, Arturo Zazpe, Elena Castro
Publikováno v: Neuropharmacology. 51:129-140
In order to better define the role of 5-HT(1A) receptors in the modulation of extrapyramidal motor functions, we investigated the effect of 5-HT(1A) agonists on tacrine-induced tremulous jaw movements (TJM) in rats, a putative model of parkinsonian t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d09cd56e94aa17a46083b27c3e1d584
https://doi.org/10.1016/j.neuropharm.2006.03.008
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8
Preclinical pharmacology of F-98214-TA, a novel potent serotonin and norepinephrine uptake inhibitor with antidepressant and anxiolytic properties
Autor: Luis Labeaga, Ana Innerárity, Elena Castro, Ruth Pena, Arturo Zazpe, Angel Pazos, Álvaro Díaz, Inés Artaiz, Aurelio Orjales, José Ángel Ruiz-Ortega, Elena del Olmo
Publikováno v: Psychopharmacology. 182:400-413
Serotonin (5-HT) and norepinephrine (NE) re-uptake inhibitors (SNRIs) have been proposed to have a higher efficacy and/or faster onset of action than previously available antidepressants.We examined in biochemical, electrophysiological and behavioura
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b273616da177e2f24726f340626fa2
https://doi.org/10.1007/s00213-005-0087-3
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9
Reversal of learned helplessness by selective serotonin reuptake inhibitors in rats is not dependent on 5-HT availability
Autor: Luis Labeaga, Arturo Zazpe, Inés Artaiz, Maria Luisa Lucero, Aurelio Orjales
Publikováno v: Neuropharmacology. 52(3)
Serotonin (5-HT) and 5-HT(1A) receptors have been suggested to play a pivotal role in the mechanism of action of antidepressant drugs, particularly in the case of selective serotonin reuptake inhibitors (SSRIs). In the rat learned helplessness (LH) p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7101dc5bc2975009e115c20acb4f9a2c
https://pubmed.ncbi.nlm.nih.gov/17141811
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