Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Arturas Ziemys"'
Autor:
Lufei Sui, Suming Wang, Debolina Ganguly, Tyler P. El Rayes, Cecilie Askeland, Astrid Børretzen, Danielle Sim, Ole Johan Halvorsen, Gøril Knutsvik, Jarle Arnes, Sura Aziz, Svein Haukaas, William D. Foulkes, Diane R. Bielenberg, Arturas Ziemys, Vivek Mittal, Rolf A. Brekken, Lars A. Akslen, Randolph S. Watnick
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Tsp-1 in the tumor microenvironment is known to suppress tumor growth and progression. Here the authors show that PRSS2 represses Tsp-1 by binding to lipoprotein receptor-related protein 1 and suggest targeting PRSS2 mediated Tsp-1 repression as a po
Externí odkaz:
https://doaj.org/article/83a9a2de5a4d485e91ed34a5fbcd3d45
Autor:
Yuqing Zhang, Huocong Huang, Morgan Coleman, Arturas Ziemys, Purva Gopal, Syed M. Kazmi, Rolf A. Brekken
Publikováno v:
JCI Insight, Vol 6, Iss 23 (2021)
Angiogenesis, a hallmark of cancer, is induced by vascular endothelial growth factor–A (hereafter VEGF). As a result, anti-VEGF therapy is commonly used for cancer treatment. Recent studies have found that VEGF expression is also associated with im
Externí odkaz:
https://doaj.org/article/678c51832205427eb6542fc20f36712b
Publikováno v:
Advanced NanoBiomed Research, Vol 1, Iss 10, Pp n/a-n/a (2021)
Treatment of peritoneal surface malignancies with cytoreductive surgery and HIPEC (CRS/HIPEC) has a substantial risk of local recurrence and causes off‐target toxicity. HIPEC is reinvented utilizing a gold nanorod (GNR) platform to provide surgical
Externí odkaz:
https://doaj.org/article/6d272152b8384266b9192c9d37161942
Publikováno v:
Translational Oncology, Vol 12, Iss 9, Pp 1196-1205 (2019)
Insufficient delivery of systemically administered anticancer drugs to tumors can compromise therapeutic efficacy and develop drug delivery-based therapeutic resistance. Nanotherapeutics such as PEGylated liposomal doxorubicin (PLD) are designed to p
Externí odkaz:
https://doaj.org/article/6335f5a5acaf438f83ed4a629ed53b3e
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Melanoma is the most lethal form of skin cancer in the United States. Current American Joint Committee on Cancer (AJCC) staging uses Breslow depth and ulceration as the two primary tumor factors that predict metastatic risk in cutaneous melanoma. Ear
Externí odkaz:
https://doaj.org/article/bee50c5a80fe458c8778fc8b05f959fe
Autor:
Ashley M. Holder, Arturas Ziemys
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BackgroundIn staging patients with clinical stage I-II melanoma, the sentinel lymph node (SLN) is the most important prognostic indicator; however, the false negative rate of SLN biopsy (SLNB) is 15%.MethodsNine patients with clinical Stage I-II mela
Externí odkaz:
https://doaj.org/article/3a38cdbd2c3a4c1985e907da4ebc1765
Autor:
Arturas Ziemys, Michelle Kim, Alexander M. Menzies, James S. Wilmott, Georgina V. Long, Richard A. Scolyer, Larry Kwong, Ashley Holder, Genevieve Boland
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Metastatic melanoma is one of the most immunogenic malignancies due to its high rate of mutations and neoantigen formation. Response to BRAF inhibitors (BRAFi) may be determined by intratumoral immune activation within melanoma metastases. To evaluat
Externí odkaz:
https://doaj.org/article/e302608702ac4532a6eebc3e2caa76f9
Autor:
Milos Kojic, Miljan Milosevic, Vladimir Simic, Bogdan Milicevic, Vladimir Geroski, Sara Nizzero, Arturas Ziemys, Nenad Filipovic, Mauro Ferrari
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Mass transport represents the most fundamental process in living organisms. It includes delivery of nutrients, oxygen, drugs, and other substances from the vascular system to tissue and transport of waste and other products from cells back to vascula
Externí odkaz:
https://doaj.org/article/ff0fe0f9e329427c8299652c4c79392c
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 703 (2021)
Metastatic cancer disease is the major cause of death in cancer patients. Because those small secondary tumors are clinically hardly detectable in their early stages, little is known about drug biodistribution and permeation into those metastatic tum
Externí odkaz:
https://doaj.org/article/d6279f3f919b476fb5fd88ce0997eb4d
Autor:
Yan Ting Liu, Shreya Goel, Megumi Kai, Jose Alberto Moran Guerrero, Thao Nguyen, Junhua Mai, Haifa Shen, Arturas Ziemys, Kenji Yokoi
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 530 (2021)
We sought to determine if Stephen Paget’s “seed and soil” hypothesis of organ-preference patterns of cancer metastasis can explain the development of heterogeneity in a tumor microenvironment (TME) as well as immunotherapeutic delivery and effi
Externí odkaz:
https://doaj.org/article/e303172421e04154a9ed7e6c895b94e4