Recent applications of magnesium- and Zinc-TMP amides in the synthesis of bioactive targets

Autor: Leandro A. Bozzini, Artur de L. L. Vaz, Giuliano C. Clososki, Rodolfo H. V. Nishimura, Valter E. Murie

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Magnesium- and zinc-TMP amides have come out from relative obscurity to be recognized as important tools in modern synthetic chemistry. Development of LiCl-activated metal amides like TMPMgCl·LiCl and TMP2Zn·2MgCl2·2LiCl has been important to obta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff9a99b67e4b6475a6ca69e54f0c95b
https://doi.org/10.1016/j.tet.2018.12.018

Interspecific chemical communication in raids of the robber bee Lestrimelitta limao

Autor: José Maurício Simões Bento, Artur de L. L. Vaz, Arodi P. Favaris, Giuliano C. Clososki, Dirk Louis P. Schorkopf, L. G. Elias, L. G. von Zuben, Túlio M. Nunes

Publikováno v: Insectes Sociaux. 63:339-347

Most social bees collect floral resources to obtain proteins and carbohydrates. However, the obligate cleptoparasite stingless bee Lestrimelitta limao, the so-called robber bee, is a rare exception as it collects resources by raiding other stingless

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c70550de302b1ea16aae017fdf95e0cb
https://doi.org/10.1007/s00040-016-0474-2

Simultaneous determination of dipyrone metabolites in rat hypothalamus, cerebrospinal fluid and plasma samples by LC–MS/MS

Autor: Cristiane Masetto de Gaitani, Giuliano C. Clososki, Glória Emília Petto de Souza, Valquíria A. P. Jabor, Leandro Augusto Calixto, David do Carmo Malvar, Artur de L. L. Vaz, Fernando Armani Aguiar

Publikováno v: Bioanalysis. 5:2631-2645

Background: After oral administration dipyrone is rapidly hydrolyzed to 4-methylaminoantipyrine, which is absorbed and further metabolized to 4-formylaminoantipyrine and to 4-aminoantipyrine, which is acetylated by a polymorphic N-acetyltransferase s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bde69d018396b4673841e9040162826
https://doi.org/10.4155/bio.13.229

Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever

Autor: David do C, Malvar, Fernando A, Aguiar, Artur de L L, Vaz, Débora C R, Assis, Miriam C C, de Melo, Valquíria A P, Jabor, Evanguedes, Kalapothakis, Sérgio H, Ferreira, Giuliano C, Clososki, Glória E P, de Souza

Publikováno v: British journal of pharmacology. 171(15)

The antipyretic and hypothermic prodrug dipyrone prevents PGE2 -dependent and -independent fever induced by LPS from Escherichia coli and Tityus serrulatus venom (Tsv) respectively. We aimed to identify the dipyrone metabolites responsible for the an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e37b63355cf1bead9d0a9b9997b6da7
https://pubmed.ncbi.nlm.nih.gov/24712707