Výsledky vyhledávání - "Artur J, Ulmer"

Regulation of fetal hemoglobin expression during hematopoietic stem cell development and its importance in bone metabolism and osteoporosis

Autor: Adrian Heini, Kai Yu, Artur J. Ulmer, Ulrich Zähringer, D Heumann, R.M. Gorczynski, Ernst Th. Rietschel, Klaus Brandenburg, Christian Alexander, Zhiqi Chen, O. Kos, Thierry Waelli, Jean-Pierre Mach, A. Tersikh, Ismat A Khatri

Publikováno v: International Immunopharmacology. 57:112-120

We have shown that an altered tissue redox environment in mice lacking either murine beta Hemoglobin major (Hgbβ ma KO) or minor (Hgbβ mi KO) regulates inflammation. The REDOX environment in marrow stem cell niches also control differentiation path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544d09b1f4602d14b747b48e78ab3556
https://doi.org/10.1016/j.intimp.2018.02.010

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Akademický článek

Natural killer T cells activated by a lipopeptidophosphoglycan from Entamoeba histolytica are critically important to control amebic liver abscess.

Autor: Hannelore Lotter, Nestor González-Roldán, Buko Lindner, Florian Winau, Armando Isibasi, Martha Moreno-Lafont, Artur J Ulmer, Otto Holst, Egbert Tannich, Thomas Jacobs

Publikováno v: PLoS Pathogens, Vol 5, Iss 5, p e1000434 (2009)

The innate immune response is supposed to play an essential role in the control of amebic liver abscess (ALA), a severe form of invasive amoebiasis due to infection with the protozoan parasite Entamoeba histolytica. In a mouse model for the disease,

Externí odkaz: https://doaj.org/article/a549906b0f0e491bb5dc281972fb223f

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Analysis of cytokine immune response profile in response to inflammatory stimuli in mice with genetic defects in fetal and adult hemoglobin chain expression

Autor: Artur J. Ulmer, Alexey V. Terskikh, Zhiqi Chen, Ernst Th. Rietschel, Christian Alexander, Klaus Brandenburg, Adrian Heini, D Heumann, Ulrich Zähringer, Vienna Mazzoli, Jean-Pierre Mach, Reginald M. Gorczynski, Ismat A Khatri, Kai Yu

Publikováno v: The Pharmacogenomics Journal. 18:546-555

Injections of a crude fetal sheep liver extract (FSLE) containing fetal hemoglobin, MPLA, and glutathione (GSSH) reversed cytokine changes in aged mice. To investigate the role of fetal hemoglobin we derived mice with homzygous deletions for either o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e08520f8a484d1c118696da39142b01
https://doi.org/10.1038/s41397-017-0008-y

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An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression

Autor: Adrian Heini, Ismat A Khatri, Ulrich Zähringer, R.M. Gorczynski, Christian Alexander, Jean-Pierre Mach, D. Neumann, Ernst Th. Rietschel, Klaus Brandenburg, A. Tersikh, Artur J. Ulmer, Zhiqi Chen, Kai Yu

Publikováno v: International Immunopharmacology. 50:69-76

C5BL/6 female mice receiving dextran sodium sulfate in their drinking water develop an acute inflammatory colitis within 7 d, with weight loss, histopathologic signs of inflammation, and colonic expression of inflammatory cytokines. In previous studi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec08d99fa4e17e5293855a4616a5801
https://doi.org/10.1016/j.intimp.2017.06.003

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A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia

Autor: Bruno Galy, Martina U. Muckenthaler, Claudia Guida, Michael Boutros, Sandro Altamura, Artur J. Ulmer, Matthias W. Hentze, Felix A. Klein

Publikováno v: Blood. 125:2265-2275

Regulation of iron metabolism and innate immunity are tightly interlinked. The acute phase response to infection and inflammation induces alterations in iron homeostasis that reduce iron supplies to pathogens. The iron hormone hepcidin is activated b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c16b45a3d07324b130eb41c7d460a7f
https://doi.org/10.1182/blood-2014-08-595256

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Dermatophagoides pteronyssinus Major Allergen 1 Activates the Innate Immune Response of the Fruit Fly Drosophila melanogaster

Autor: Florentina Rus, Christine Warmbold, Roland Suck, Arnd Petersen, Artur J. Ulmer, Thomas Roeder, Karin Uliczka, Neal S. Silverman, Holger Heine

Publikováno v: The Journal of Immunology. 190:366-371

Some allergens with relevant protease activity have the potential to directly interact with host structures. It remains to be elucidated whether this activity is relevant for developing their allergenic properties. The major goal of this study was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2718900c1d77d678cb654b1dff35a65
https://doi.org/10.4049/jimmunol.1201347

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Timothy grass pollen major allergen Phl p 1 activates respiratory epithelial cells by a non-protease mechanism

Autor: P. König, Katja Farhat, Roland Suck, Kristina Röschmann, Artur J. Ulmer, Arnd Petersen

Publikováno v: Clinical & Experimental Allergy. 39:1358-1369

Summary Background Group 1 allergens from grass pollen (e.g. Phl p 1, the major allergen of timothy grass Phleum pratense) cause IgE reactivity in about 95% of allergic subjects and exist in all grass species. The respiratory epithelium represents a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db667cf33c98358c52c660a3ad2f601e
https://doi.org/10.1111/j.1365-2222.2009.03291.x

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