Day 14 Bone Marrow Evaluation During Acute Myeloid Leukemia Induction in a Real-world Canadian Cohort

Autor: Donna L. Forrest, Thomas J. Nevill, Maryse M. Power, James T. England, Florian Kuchenbauer, David Sanford, Donna E. Hogge, Joseph Brandwein, Lalit Saini, Monika Hudoba, Sujaatha Narayanan, Artur J. Szkotak

Publikováno v: Clinical lymphoma, myelomaleukemia. 20(7)

The 2017 National Comprehensive Cancer Network guidelines for acute myeloid leukemia have recommended performing bone marrow (BM) aspiration and BM trephine biopsy (BMTB) 14 to 21 days after starting induction therapy (commonly referred to as "day 14

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e753f92001bfc97286ccb2eb7524eb2
https://pubmed.ncbi.nlm.nih.gov/32201130

Crystals and Fatty Acid Abnormalities Are Not Present in Circulating Cells From Choroideremia Patients

Autor: Woo Jung Cho, Alina Radziwon, Miyoung Suh, Ian M. MacDonald, Artur J. Szkotak

Publikováno v: Investigative ophthalmologyvisual science. 59(11)

Purpose To confirm whether choroideremia (CHM) is a systemic disease characterized by blood lipid abnormalities and crystals found in, or associated with, circulating peripheral blood cells of patients. Methods Peripheral blood samples obtained from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1273f07b232bccb979efb0aad6a4e0a
https://pubmed.ncbi.nlm.nih.gov/30193321

Persistent cytogenetic abnormalities in patients undergoing intensive chemotherapy for acute myeloid leukemia

Autor: Sunita Ghosh, Joseph Brandwein, Irwindeep Sandhu, Artur J. Szkotak, Lalit Saini

Publikováno v: Leukemialymphoma. 59(1)

We evaluated the impact of bone marrow sample characteristics on the detection of persistent cytogenetic abnormalities (PCA) following induction chemotherapy for acute myeloid leukemia (AML). PCA's were identified in 20.4% of patients and were more c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3516b3c22c7c23d49161cd6ba280c19c
https://pubmed.ncbi.nlm.nih.gov/28540755

A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders

Autor: Sol Schulman, Daniel J. Hampshire, Jennifer Jolley, Peter A. Smethurst, Willem H. Ouwehand, Alan T. Nurden, Ilenia Simeoni, William Stevenson, Paolo Gresele, Ri Liesner, Kathleen Freson, Christel Van Geet, Walter H. A. Kahr, Tadbir K. Bariana, Paquita Nurden, Minka J A Vries, David A. Wilcox, Mary Mathias, Fengyuan Hu, Maha Othman, Marguerite Neerman-Arbez, Pawan Poudel, Matthias Ballmaier, Pieter H. Reitsma, Peter William Collins, Jose A. Lopez, Artur J. Szkotak, Jose A. Guerrero, Marie-Christine Alessi, Manuela Germeshausen, Jonathan Stephens, Cedric Ghevaert, Michael Gattens, Carolyn M. Millar, Gareth Baynam, Marian Hill, Marco Cattaneo, Antony P. Attwood, Shoshana Revel-Vilk, Matthew T. Rondina, Anne M. Kelly, Sri V V Deevi, Sofia Papadia, Amit C. Nathwani, Paul F. Bray, Daniel B. Bellissimo, Michael Laffan, Deborah L. French, Daniel P. Hart, Shinji Kunishima, Bin Zhang, Rutendo Mapeta, Salih Tuna, Anne Goodeve, Keith Gomez, Nancy Hogg, Ernest Turro, Johan W. M. Heemskerk, Marta Bertoli, Karyn Megy, Ron Kerr, Christopher J. Penkett, David J. Perry, Claire Lentaigne, Deborah Whitehorn, Daniel Greene, Suthesh Sivapalaratnam, Myrto Kostadima, Andrew D Mumford, Bruce Furie, Emilse Bermejo, Rémi Favier, Michele P. Lambert, Louise C. Daugherty, Yvonne M. C. Henskens, Augusto Rendon, Loredana Bury, Kathelijne Peerlinck, Sarah K Westbury

Publikováno v: Blood
Blood, American Society of Hematology, 2016, 127 (23), pp.2791-803. ⟨10.1182/blood-2015-12-688267⟩
Simeoni, I, Stephens, J C, Hu, F, Deevi, S V V, Megy, K, Bariana, T K, Lentaigne, C, Schulman, S, Sivapalaratnam, S, Vries, M J A, Westbury, S K, Greene, D, Papadia, S, Alessi, M-C, Attwood, A P, Ballmaier, M, Baynam, G, Bermejo, E, Bertoli, M, Bray, P F, Bury, L, Cattaneo, M, Collins, P, Daugherty, L C, Favier, R, French, D L, Furie, B, Gattens, M, Germeshausen, M, Ghevaert, C, Goodeve, A, Guerrero, J, Hampshire, D J, Hart, D P, Heemskerk, J W M, Henskens, Y M C, Hill, M, Hogg, N, Jolley, J D, Kahr, W H, Kelly, A M, Kerr, R, Kostadima, M, Kunishima, S, Lambert, M P, Liesner, R, Lopez, J, Mapeta, R P, Mathias, M, Millar, C M, Nathwani, A, Neerman-Arbez, M, Nurden, A T, Nurden, P, Othman, M, Peerlinck, K, Perry, D J, Poudel, P, Reitsma, P, Rondina, M, Smethurst, P A, Stevenson, W, Szkotak, A, Tuna, S, van Geet, C, Whitehorn, D, Wilcox, D A, Zhang, B, Revel-Vilk, S, Gresele, P, Bellissimo, D, Penkett, C J, Laffan, M A, Mumford, A D, Rendon, A, Gomez, K, Freson, K, Ouwehand, W H & Turro, E 2016, ' A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorderdisorders ', Blood, vol. 127, no. 23, pp. 2791-2803 . https://doi.org/10.1182/blood-2015-12-688267
Blood, 127(23), 2791-2803
Blood, 127(23), 2791-2803. The American Society of Hematology

Inherited bleeding, thrombotic and platelet disorders (BPDs) are diseases affecting approximately 300 individuals per million births. With the exception of haemophilia and von Willebrand disease patients, a molecular analysis for patients with a BPD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa352cd1eafdc5697d70b553f05b0503
http://hdl.handle.net/11391/1386441

The Role of the Basolateral Outwardly Rectifying Chloride Channel in Human Airway Epithelial Anion Secretion

Autor: S. F. Paul Man, Artur J. Szkotak, Marek Duszyk

Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 29:710-720

The purpose of this study was to characterize basolateral anion channels in Calu-3 and normal human bronchial epithelial cells, and their role in anion secretion. Patch clamp studies identified an outwardly rectifying Cl- channel (ORCC), which could

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b364d18e5f2fd55a6d5f0291f21477fe
https://doi.org/10.1165/rcmb.2003-0109oc