Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Artur, Sargun"'
Autor:
Romana R. Gerner, Suzana Hossain, Artur Sargun, Kareem Siada, Grant J. Norton, Tengfei Zheng, Wilma Neumann, Sean-Paul Nuccio, Elizabeth M. Nolan, Manuela Raffatellu
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the gastrointestinal tract and profound alterations to the gut microbiome. Adherent-invasive Escherichia coli (AIEC) is a mucosa-associated pathobiont that coloni
Externí odkaz:
https://doaj.org/article/1b65887a6d9f4da093e24d1064d852d9
Autor:
Artur Sargun, Allison L. Fisher, Anna S. Wolock, Sydney Phillips, Mozhdeh Sojoodi, Soumya Khanna, Jodie L. Babitt, Eric M. Gale
Publikováno v:
Journal of the American Chemical Society. 145:6871-6879
Publikováno v:
CHIMIA, Vol 72, Iss 6 (2018)
Peptide nucleic acid (PNA) is a synthetic analogue of DNA in which the natural nucleobases A, G, C, and T are linked to an achiral, charge neutral, pseudopeptide backbone. PNA strands can form double helices similar to DNA whose helical sense can be
Externí odkaz:
https://doaj.org/article/869d6bc349e1471f83a44847138718ce
Publikováno v:
Chemical Science
Chemical science, vol 12, iss 11
Chemical science, vol 12, iss 11
The design and synthesis of narrow-spectrum antibiotics that target a specific bacterial strain, species, or group of species is a promising strategy for treating bacterial infections when the causative agent is known. In this work, we report the syn
Autor:
Sunil Saxena, Artur Sargun, Junmei Wang, Austin Gamble Jarvi, Xiaowei Bogetti, Catalina Achim
Publikováno v:
The Journal of Physical Chemistry B. 124:7544-7556
Peptide nucleic acids (PNA) are a promising group of synthetic analogues of DNA and RNA that offer several distinct advantages over the naturally-occurring nucleic acids for applications such as bi...
Publikováno v:
ACS Infect Dis
The pathogen Salmonella enterica is a leading cause of infection worldwide. Nontyphoidal Salmonella (NTS) serovars typically cause inflammatory diarrhea in healthy individuals, and can cause bacteremia in immunocompromised patients, children, and the
Publikováno v:
J Infect Dis
Infections caused by Gram-negative bacteria can be challenging to treat due to the outer membrane permeability barrier and the increasing emergence of antibiotic resistance. During infection, Gram-negative pathogens must acquire iron, an essential nu
Autor:
Austin, Gamble Jarvi, Artur, Sargun, Xiaowei, Bogetti, Junmei, Wang, Catalina, Achim, Sunil, Saxena
Publikováno v:
The journal of physical chemistry. B. 124(35)
Peptide nucleic acids (PNAs) are a promising group of synthetic analogues of DNA and RNA that offer several distinct advantages over the naturally occurring nucleic acids for applications in biosensing, drug delivery, and nanoelectronics. Because of
Autor:
Artur Sargun, Selma Ulku, Catalina Achim, Edward Beall, David H. Waldeck, Yookyung Bae, Caleb Clever, Emil Wierzbinski
Publikováno v:
The Journal of Physical Chemistry C. 122:7533-7540
This work investigates how the conductance of a nucleic acid duplex with a “nick” in its backbone compares with that of a duplex with a fully covalent backbone. Statistical analyses of the single-m...
Autor:
Elizabeth M. Nolan, Suzana Hossain, Romana R. Gerner, Wilma Neumann, Manuela Raffatellu, Kareem Siada, Artur Sargun
Publikováno v:
Gastroenterology. 160:S45
The pathovar adherent-invasive Escherichia coli (AIEC) is a mucosa-associated bacterium that is frequently found in patients with Crohn’s disease (CD), but targeted treatment options are currently lacking. During intestinal inflammation, host-media