Výsledky vyhledávání - "Arto Tapio, Pulliainen"

Akademický článek

Systemic analysis of gene expression profiles identifies ErbB3 as a potential drug target in pediatric alveolar rhabdomyosarcoma.

Autor: Janne Nordberg, John Patrick Mpindi, Kristiina Iljin, Arto Tapio Pulliainen, Markku Kallajoki, Olli Kallioniemi, Klaus Elenius, Varpu Elenius

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e50819 (2012)

Pediatric sarcomas, including rhabdomyosarcomas, Ewing's sarcoma, and osteosarcoma, are aggressive tumors with poor survival rates. To overcome problems associated with nonselectivity of the current therapeutic approaches, targeted therapeutics have

Externí odkaz: https://doaj.org/article/bb05e23f4e6d442f98e303fc92e8b5cc

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Molecular basis of H2O2 resistance mediated by Streptococcal Dpr. Demonstration of the functional involvement of the putative ferroxidase center by site-directed mutagenesis in Streptococcus suis

Autor: Arto Tapio, Pulliainen, Sauli, Haataja, Sanni, Kähkönen, Jukka, Finne

Publikováno v: The Journal of biological chemistry. 278(10)

H(2)O(2) is an unavoidable cytotoxic by-product of aerobic life. Dpr, a recently discovered member of the Dps protein family, provides a means for catalase-negative bacteria to tolerate H(2)O(2). Potentially, Dpr could bind free intracellular iron an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88901afc681dd1bd5dea3a04c56a319a
https://pubmed.ncbi.nlm.nih.gov/12501248

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