Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Artjohn Villafania"'
Autor:
Katherine Young, Ronald E. Painter, Susan L. Raghoobar, Nichelle N. Hairston, Fred Racine, Douglas Wisniewski, Carl J. Balibar, Artjohn Villafania, Rumin Zhang, Daniel F. Sahm, Timothy Blizzard, Nicholas Murgolo, Milton L. Hammond, Mary R. Motyl
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background The prevalence of antibiotic resistance is increasing, and multidrug-resistant Pseudomonas aeruginosa has been identified as a serious threat to human health. The production of β-lactamase is a key mechanism contributing to imipe
Externí odkaz:
https://doaj.org/article/74bfca45a65f4093988417ba76437c53
Autor:
Mihirbaran Mandal, Li Xiao, Weidong Pan, Giovanna Scapin, Guoqing Li, Haiqun Tang, Shu-Wei Yang, Jianping Pan, Yuriko Root, Reynalda Keh de Jesus, Christine Yang, Winnie Prosise, Priya Dayananth, Asra Mirza, Alex G. Therien, Katherine Young, Amy Flattery, Charles Garlisi, Rumin Zhang, Donald Chu, Payal Sheth, Inhou Chu, Jin Wu, Carrie Markgraf, Hai-Young Kim, Ronald Painter, Todd W. Mayhood, Edward DiNunzio, Daniel F. Wyss, Alexei V. Buevich, Thierry Fischmann, Alexander Pasternak, Shuzhi Dong, Jacqueline D. Hicks, Artjohn Villafania, Lianzhu Liang, Nicholas Murgolo, Todd Black, William K. Hagmann, Jim Tata, Emma R. Parmee, Ann E. Weber, Jing Su, Haifeng Tang
Publikováno v:
Journal of Medicinal Chemistry. 65:16234-16251
With the emergence and rapid spreading of NDM-1 and existence of clinically relevant VIM-1 and IMP-1, discovery of pan inhibitors targeting metallo-beta-lactamases (MBLs) became critical in our battle against bacterial infection. Concurrent with our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72a226d0f459e4620537979c8da4d4d
https://doi.org/10.1021/acs.jmedchem.2c00766
https://doi.org/10.1021/acs.jmedchem.2c00766
Autor:
Nichelle Hairston, Katherine Young, Artjohn Villafania, Milton L. Hammond, Nicholas Murgolo, Ronald E. Painter, Douglas Wisniewski, Mary Motyl, Daniel F. Sahm, Rumin Zhang, Carl J. Balibar, Fred Racine, Timothy A. Blizzard, Susan L. Raghoobar
Publikováno v:
BMC Microbiology
BMC Microbiology, Vol 19, Iss 1, Pp 1-14 (2019)
BMC Microbiology, Vol 19, Iss 1, Pp 1-14 (2019)
Background The prevalence of antibiotic resistance is increasing, and multidrug-resistant Pseudomonas aeruginosa has been identified as a serious threat to human health. The production of β-lactamase is a key mechanism contributing to imipenem resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa66d7281d6be8c3899743e477650e1e
https://doi.org/10.1186/s12866-019-1522-7
https://doi.org/10.1186/s12866-019-1522-7
Autor:
Young, Katherine, Painter, Ronald, Raghoobar, Susan, Hairston, Nichelle, Racine, Fred, Wisniewski, Douglas, Balibar, Carl, Artjohn Villafania, Rumin Zhang, Sahm, Daniel, Blizzard, Timothy, Murgolo, Nicholas, Hammond, Milton, Motyl, Mary
Table S1. P aeruginosa isolate sources. Table S2. Primers used in the construction of P. aeruginosa RND-overexpressing strains. Table S3. Inoculum effect control data. Table S4. Susceptibility to imipenem and the combination of imipenem with relebact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011cf694b9c4312f37e4bc9c6e205dc5
Autor:
Young, Katherine, Painter, Ronald, Raghoobar, Susan, Hairston, Nichelle, Racine, Fred, Wisniewski, Douglas, Balibar, Carl, Artjohn Villafania, Rumin Zhang, Sahm, Daniel, Blizzard, Timothy, Murgolo, Nicholas, Hammond, Milton, Motyl, Mary
PDC-1 cloning and purification. (DOCX 13 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d8fb65b842d5f444a2d417705f6a96
Autor:
Young, Katherine, Painter, Ronald, Raghoobar, Susan, Hairston, Nichelle, Racine, Fred, Wisniewski, Douglas, Balibar, Carl, Artjohn Villafania, Rumin Zhang, Sahm, Daniel, Blizzard, Timothy, Murgolo, Nicholas, Hammond, Milton, Motyl, Mary
Figure S1. Mechanistic profiling by global progress curve analysis. (DOCX 81 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5224e00fcc95f7897bf2713a6c47f4dc
Autor:
Young, Katherine, Painter, Ronald, Raghoobar, Susan, Hairston, Nichelle, Racine, Fred, Wisniewski, Douglas, Balibar, Carl, Artjohn Villafania, Rumin Zhang, Sahm, Daniel, Blizzard, Timothy, Murgolo, Nicholas, Hammond, Milton, Motyl, Mary
Figure S1. Minimum inhibitory concentrations (MIC50/90, expressed in Îźg/mL) for imipenem (A) and imipenem with 4â Îźg/mL relebactam (B), mapped onto a dendrogram of P. aeruginosa PDC alleles. (PDF 1384 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac6f083e49b61e069d37c6963c46d8a
Autor:
Artjohn Villafania, Christopher M. Barbieri, Terry Roemer, Hao Wang, Thierry O. Fischmann, Li Xiao, Rumin Zhang, Haifeng Tang, John A. Howe
Publikováno v:
RNA Biology
Bacterial riboswitches are non-coding RNA structural elements that direct gene expression in numerous metabolic pathways. The key regulatory roles of riboswitches, and the urgent need for new classes of antibiotics to treat multi-drug resistant bacte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700734b4e5e5f087bcf3dc756a22a15c
https://doi.org/10.1080/15476286.2016.1216304
https://doi.org/10.1080/15476286.2016.1216304
Autor:
Carl J, Balibar, Artjohn, Villafania, Christopher M, Barbieri, Nick, Murgolo, Terry, Roemer, Hao, Wang, John A, Howe
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1787
A riboflavin biosynthesis pathway-specific phenotypic screen using a library of compounds, all with unspecified antibiotic activity, identified one small molecule later named ribocil, for which intrinsic antibacterial activity against Escherichia col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c9426710d507833ebb7b1a66f6d2190
https://pubmed.ncbi.nlm.nih.gov/29736707
https://pubmed.ncbi.nlm.nih.gov/29736707
Autor:
Artjohn Villafania, Terry Roemer, Nick Murgolo, John A. Howe, Christopher M. Barbieri, Hao Wang, Carl J. Balibar
Publikováno v:
Methods in Molecular Biology ISBN: 9781493978465
A riboflavin biosynthesis pathway-specific phenotypic screen using a library of compounds, all with unspecified antibiotic activity, identified one small molecule later named ribocil, for which intrinsic antibacterial activity against Escherichia col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d3293f17ba032a1ad21b4ab26e152fc
https://doi.org/10.1007/978-1-4939-7847-2_2
https://doi.org/10.1007/978-1-4939-7847-2_2