Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Arthur Y. Shaw"'
Publikováno v:
Multicomponent Reactions towards Heterocycles. :339-409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::528e5fce88c4937dd9b93ba2b68ea365
https://doi.org/10.1002/9783527832439.ch9
https://doi.org/10.1002/9783527832439.ch9
Publikováno v:
Organic Letters. 19:2238-2241
A new postcondensation multicomponent reaction (MCR) methodology, comprising oxidative deaminations enabling access to multiple privileged carbonyl-containing scaffolds in two steps, is described. These protocols allow facile access to functionalized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b82c8c19f5d941762987409405cd6c
https://doi.org/10.1021/acs.orglett.7b00710
https://doi.org/10.1021/acs.orglett.7b00710
Autor:
Arthur Y. Shaw, Christopher Foley, Romano V. A. Orru, Eelco Ruijter, Christopher Hulme, Jurriën W. Collet
Publikováno v:
Organic & Biomolecular Chemistry. 15:6132-6135
Herein, a two-step MCR-oxidation methodology accessing decorated 2° α-ketoamides and α-ketotetrazoles is described via a catalytic copper(i)-mediated C-N oxidation/acidic hydrolysis of Ugi-three-component and Ugi-azide reaction products. The abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c57c22f5a9f13cff27a2dc759b245f3
https://doi.org/10.1039/c7ob00881c
https://doi.org/10.1039/c7ob00881c
Publikováno v:
Organic Letters. 18:4904-4907
Two-step methodology described herein showcases the first example of an oxidation/oxidative amidation cyclization cascade of MCR products toward diverse N-functionalized isatins. Products of both the Ugi 3CR and the Ugi azide reactions are oxidativel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d654638c71a00171b7f1707be4bf0ce
https://doi.org/10.1021/acs.orglett.6b02383
https://doi.org/10.1021/acs.orglett.6b02383
Direct oxidative deamination of glyoxal-derived Ugi-azide and Ugi three-component reaction products readily affords vicinal tricarbonyls (α,β-diketoamides) and α,β-diketotetrazoles with two diversity elements. This significant extension of our pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6058e2741d06a9d37ed135b3975d7e
https://europepmc.org/articles/PMC6424580/
https://europepmc.org/articles/PMC6424580/
Autor:
Yi-Shiuan Lin1, Arthur Y Shaw2, Shi-Gang Wang1, Chia-Chen Hsu1, I-Wen Teng1, Min-Jen Tseng1, Tim HM Huang3, Ching-Shih Chen4, Yu-Wei Leu1 bioywl@ccu.edu.tw, Shu-Huei Hsiao1 bioshh@ccu.edu.tw
Publikováno v:
Journal of Biomedical Science. 2011, Vol. 18 Issue 1, p1-8. 8p. 4 Graphs.
Publikováno v:
Journal of Heterocyclic Chemistry. 51:56-61
The present study a series of (E)-5-methoxy-2-styryl-4H-pyran-4-ones 6a, 6b, 6c, 6d, 6e, 6f, 6g, 6h, 6i, 6j was synthesized and evaluated for growth inhibitory inhibition against carcinoma cells. The growth inhibition study of eight carcinoma cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47366c93dedd5f9a2fcfbf383b55dcd5
https://doi.org/10.1002/jhet.1663
https://doi.org/10.1002/jhet.1663
Publikováno v:
Synthetic Communications. 43:1538-1542
Some new di- and trisubstituted imidazole-4-carboxylates were prepared from amidoacetic acids 3 in the present report. The key step to establish such imidazole-4-carboxylates stemmed from the PBu3-mediated [3 + 2] cycloaddition between in situ–gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42e7f747152c6dfa98c96d505c005327
https://doi.org/10.1080/00397911.2011.644846
https://doi.org/10.1080/00397911.2011.644846
Publikováno v:
Synthesis. 45:459-462
This report discloses novel concise syntheses of quinoxalinones and diazepinones via a tandem oxidative amidation–deprotection–cyclization sequence. A selenium dioxide mediated oxidative amidation of arylglyoxals with secondary amines was carried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ffb85b2c3ef8920d4e0c8ef9ef32a08
https://doi.org/10.1055/s-0032-1317983
https://doi.org/10.1055/s-0032-1317983
Structure–activity relationship study of growth inhibitory 2-styrylchromones against carcinoma cells
Publikováno v:
Medicinal Chemistry Research. 22:2385-2394
The structure–activity relationship study of 2-styrylchromones against carcinoma cell growth is discussed in the present report. Taking advantage of 2-styrylchromone as a molecular template, a series of structural modifications was carried out and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31e081a83c7b71c283b907bf7d9980dc
https://doi.org/10.1007/s00044-012-0232-6
https://doi.org/10.1007/s00044-012-0232-6