Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Arthur Y. L. Shu"'
Autor:
J. Richard Heys, Arthur Y. L. Shu
Publikováno v:
Tetrahedron Letters. 41:9015-9019
Radiolabeled paclitaxel and three photophore-bearing derivatives were prepared by organoiridium-mediated direct tritium exchange under both catalytic and stoichiometric conditions. The resulting tritiated taxoids had specific activities ranging from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc45fce11c12c6c9a41aa18c729e2077
https://doi.org/10.1016/s0040-4039(00)01652-x
https://doi.org/10.1016/s0040-4039(00)01652-x
Autor:
A. J. Villani, Arthur Y. L. Shu, S. G. Senderoff, Keith T. Garnes, D. Saunders, S. H. Levinson, J. R. Heys, W. Chen
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 39:291-298
The tritium exchange labeling of a variety of complex compounds is achieved in the presence of catalyst precursor [(cod)Ir(PPh 3 ) 1 ]BF 4 and limited amounts of tritium gas. The regioselectivity of exchange is high and consistent with empirical rule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4072daaedd76787702afca2ee8f44156
https://doi.org/10.1002/(sici)1099-1344(199704)39:4<291::aid-jlcr973>3.0.co
https://doi.org/10.1002/(sici)1099-1344(199704)39:4<291::aid-jlcr973>3.0.co
Autor:
Martin Schlabach, Bo Ragnar. Tolf, Carl Djerassi, Edward Bunnenberg, Hans-Heinrich Limbach, Arthur Y. L. Shu
Publikováno v:
Journal of the American Chemical Society. 115:4554-4565
The kinetic HH/HD/DH/DD isotope effects of an intramolecular reversible nondegenerate double proton transfer reaction are described. The molecule studied is 8-acetyl-3,13,17-tris(2-(methoxycarbonyl)ethyl]-2,7,12,18-tetramethyl-(21H,23H)-porphyrin (ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1953bdfcde9f0ce3fce0ec42139fece9
https://doi.org/10.1021/ja00064a018
https://doi.org/10.1021/ja00064a018
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 28:143-153
Enantiomerically pure (2S,3R)-3-[(2-carboxyethyl)thio]-3-[2-(8-phenyloctyl)phenyl]-2-hydroxy[2-14C]propionic acid ([14C]SK&F 104353) was synthesized from methyl chloro[2-14C]acetate via a five step sequence. Darzens Condensation with 2-(8-phenyloctyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::822f76cafcac5ddfdc722a94686bb426
https://doi.org/10.1002/jlcr.2580280204
https://doi.org/10.1002/jlcr.2580280204
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 28:215-234
Tritium labeled isotopomers of (2S,3R)-3-[(2-carboxyethyl)thio]-3-[2-(8-phenyloctyl)phenyl]-2-hydroxypropionic acid (SK&F 104353) with high specific activity were prepared by catalytic tritiation of the corresponding halogenated and unsaturated precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df93bbea0e65dd72de0fcf73a4185a11
https://doi.org/10.1002/jlcr.2580280213
https://doi.org/10.1002/jlcr.2580280213
Autor:
Furfine Eric Steven, Mary H. Hanlon, H. Luke Carter, Vicente Samano, Dana P. Danger, Arthur Y. L. Shu, David J.T. Porter, Istvan Kaldor, John F. Miller, Andrew Spaltenstein
Publikováno v:
Biochemistry. 43(45)
The arylsulfonamide derivatives described herein were such potent inhibitors of human immunodeficiency virus type 1 (HIV-1) protease (enzyme, E) that values for the inhibition constants (K(i)) could not be determined by conventional steady-state kine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c1b70e951a28f8c405e9d69d651162
https://pubmed.ncbi.nlm.nih.gov/15533054
https://pubmed.ncbi.nlm.nih.gov/15533054
Autor:
Thomas D. Meek, Lawrence J. Hyland, J. Richard Heys, Michael L. Moore, Brian D. Dayton, Arthur Y. L. Shu
Publikováno v:
Analytical biochemistry. 188(2)
A rapid, high-throughput radiometric assay for HIV-1 protease has been developed using ion-exchange chromatography performed in 96-well filtration plates. The assay monitors the activity of the HIV-1 protease on the radiolabeled form of a heptapeptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d506a0481be007db90e0fbc7635e39
https://pubmed.ncbi.nlm.nih.gov/2221392
https://pubmed.ncbi.nlm.nih.gov/2221392
Autor:
Peter S. Clezy, Arthur Y. L. Shu, Yucheng Lu, A. Knierzinger, Carl Djerassi, Edward Bunneberg
Publikováno v:
Tetrahedron Letters. 24:2433-2436
The unexpected observation of a pair of oppositely signed MCD bands within the Q x O transition of monoacetyl porphyrins is related to the existence of equilibria between NH proton tautomers and/or confomational populations of the acetyl substitue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d238237e66c3332961d5d4e858aade9
https://doi.org/10.1016/s0040-4039(00)81947-4
https://doi.org/10.1016/s0040-4039(00)81947-4
Autor:
Carl Djerassi, Arthur Y. L. Shu
Publikováno v:
Tetrahedron Letters. 22:4627-4630
Using a Claisen ortho-ester rearrangement, the biogenetically important marine sterol dinosterol and its C-24 epimer were synthesized stereospecifically by a sequence which is also attractive for selective isotope labelling in the side chain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fab43b55e3f21c193a0df185a06fb71a
https://doi.org/10.1016/s0040-4039(01)82998-1
https://doi.org/10.1016/s0040-4039(01)82998-1
Publikováno v:
The Journal of Organic Chemistry. 49:3327-3336
Synthese et etude de dichroisme de trimethyl-2,12,18 porphyrinetripropionates-3,13,17 de trialkyle substitues en 8 par acetyl, vinyl, formyl, cyano ou ethoxycarbonyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0247fc2229aff5f9cad6ad8436a53db
https://doi.org/10.1021/jo00192a015
https://doi.org/10.1021/jo00192a015