Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Arthur Wingerter"'
Autor:
Nicole Ziegler, Mariela Cortés-López, Francesca Alt, Maximilian Sprang, Arsenij Ustjanzew, Nadine Lehmann, Khalifa El Malki, Arthur Wingerter, Alexandra Russo, Olaf Beck, Sebastian Attig, Lea Roth, Julian König, Claudia Paret, Jörg Faber
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTDespite massive improvements in the treatment of B-ALL through CART-19 immunotherapy, a large number of patients suffer a relapse due to loss of the targeted epitope. Mutations in the CD19 locus and aberrant splicing events are known to accou
Externí odkaz:
https://doaj.org/article/2b706a5b32624427bf13e1bdcb10eeb5
Autor:
Sebastian Göbel, Arthur Wingerter, Jürgen H. Prochaska, Andreas Schulz, Marie A. Neu, Nicole Henninger, Claudia Spix, Manfred Beutel, Karl Lackner, Thomas Münzel, Carolyn S. Lam, Hiltrud Merzenich, Jörg Faber, Philipp S. Wild
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 19 (2023)
Background The CVSS (Cardiac and Vascular Late Sequelae in Long‐Term Survivors of Childhood Cancer) study aimed to investigate the prevalence of different stages of heart failure (HF) in childhood cancer survivors (CCSs) compared with the general p
Externí odkaz:
https://doaj.org/article/34a0e504c0ab49b29c48ae0627ccd094
Autor:
Khalifa El Malki, Pia Wehling, Francesca Alt, Roger Sandhoff, Sebastian Zahnreich, Arsenij Ustjanzew, Carolin Wilzius, Marc A. Brockmann, Arthur Wingerter, Alexandra Russo, Olaf Beck, Clemens Sommer, Malte Ottenhausen, Katrin B. M. Frauenknecht, Claudia Paret, Jörg Faber
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9905 (2023)
H3K27M mutant (mut) diffuse midline glioma (DMG) is a lethal cancer with no effective cure. The glycosphingolipids (GSL) metabolism is altered in these tumors and could be exploited to develop new therapies. We tested the effect of the glucosylcerami
Externí odkaz:
https://doaj.org/article/bd10c60feb484b64aa9578c048a1bae4
Autor:
Juliane Burghardt, Eva Klein, Elmar Brähler, Mareike Ernst, Astrid Schneider, Susan Eckerle, Marie Astrid Neu, Arthur Wingerter, Nicole Henninger, Marina Panova‐Noeva, Jürgen Prochaska, Philipp Wild, Manfred Beutel, Jörg Faber
Publikováno v:
Cancer Medicine, Vol 8, Iss 4, Pp 1865-1874 (2019)
Abstract Background Increasing survival rates after childhood cancer have raised the issue of long‐term mental health consequences in adulthood. This study determines mental health distress among long‐term survivors of pediatric cancer and compar
Externí odkaz:
https://doaj.org/article/4b20f6d05e264f779596d3f909ec65e8
Autor:
Natalie Arnold, Hiltrud Merzenich, Arthur Wingerter, Andreas Schulz, Astrid Schneider, Jürgen H. Prochaska, Sebastian Göbel, Marie A. Neu, Nicole Henninger, Marina Panova‐Noeva, Susan Eckerle, Claudia Spix, Irene Schmidtmann, Karl J. Lackner, Manfred E. Beutel, Norbert Pfeiffer, Thomas Münzel, Jörg Faber, Philipp S. Wild
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 5 (2021)
Background Vascular alterations induced by antineoplastic treatment might be considered as a possible underlying mechanism of increased cardiovascular sequelae in childhood cancer survivors (CCSs). We aimed to evaluate arterial stiffness among long
Externí odkaz:
https://doaj.org/article/cead5c07c5e94a6c861e3c7a79ffc7e8
Autor:
Nadine Lehmann, Claudia Paret, Khalifa El Malki, Alexandra Russo, Marie Astrid Neu, Arthur Wingerter, Larissa Seidmann, Sebastian Foersch, Nicole Ziegler, Lea Roth, Nora Backes, Roger Sandhoff, Joerg Faber
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Papillary renal cell carcinoma (PRCC) is a rare entity in children with no established therapy protocols for advanced diseases. Immunotherapy is emerging as an important therapeutic tool for childhood cancer. Tumor cells can be recognized and killed
Externí odkaz:
https://doaj.org/article/e138c3c0e30c4a50b0b943bb2fc60865
Autor:
Sandra Stössel, Marie A. Neu, Arthur Wingerter, Wilhelm Bloch, Philipp Zimmer, Claudia Paret, Khalifa El Malki, Freerk T. Baumann, Alexandra Russo, Nicole Henninger, Nadine Lehmann, Henrike Otto, Jörg Faber
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Objective: In cancer patients, the impairment in muscle function is a frequently observed phenomenon. However, comprehensive evaluation of the effect of exercise training on muscle function in childhood cancer patients (CCPs) is sparse and therefore
Externí odkaz:
https://doaj.org/article/4c37caae9ca7403baef8bdd3b80d3a74
Autor:
Natalie Arnold, Hiltrud Merzenich, Arthur Wingerter, Andreas Schluz, Astrid Schneider, Jürgen H. Prochaska, Sebastian Göbel, Marie-Astrid Neu, Nicole Henninger, Marina Panova-Noeva, Susan Eckerle, Claudia Spix, Irene Schidtmann, Karl J. Lackner, Manfred E. Beutel, Norbert Pfeiffer, Thomas Münzel, Jörg Faber, Philipp S. Wild
Publikováno v:
Artery Research, Vol 24 (2018)
Background: Vascular alterations induced by antineoplastic treatment might be considered as a possible underlying mechanism of increased cardiovascular (CV) sequelae in childhood cancer survivors (CCS). Therefore, we thought to evaluate the changes i
Externí odkaz:
https://doaj.org/article/a457635af1db4a5e85b005e7f7bac475
Autor:
Alexandra Russo, Claudia Paret, Francesca Alt, Jürgen Burhenne, Margaux Fresnais, Wolfgang Wagner, Martin Glaser, Hannah Bender, Sabrina Huprich, Patrick N. Harter, Katharina Filipski, Nadine Lehmann, Nora Backes, Lea Roth, Larissa Seidmann, Clemens Sommer, Marc A. Brockmann, Torsten Pietsch, Marie A. Neu, Arthur Wingerter, Jörg Faber
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4267 (2019)
The insulin-like growth factor (IGF) pathway plays an important role in several brain tumor entities. However, the lack of inhibitors crossing the blood−brain barrier remains a significant obstacle for clinical translation. Here, we targeted the IG
Externí odkaz:
https://doaj.org/article/1e910f23e4c146c898b6d61725250cc8
Autor:
Faber, Khalifa El Malki, Pia Wehling, Francesca Alt, Roger Sandhoff, Sebastian Zahnreich, Arsenij Ustjanzew, Carolin Wilzius, Marc A. Brockmann, Arthur Wingerter, Alexandra Russo, Olaf Beck, Clemens Sommer, Malte Ottenhausen, Katrin B. M. Frauenknecht, Claudia Paret, Jörg
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9905
H3K27M mutant (mut) diffuse midline glioma (DMG) is a lethal cancer with no effective cure. The glycosphingolipids (GSL) metabolism is altered in these tumors and could be exploited to develop new therapies. We tested the effect of the glucosylcerami