Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Arthur R. Frampton"'
Autor:
Jeanette B. Black, Arthur R. Frampton
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Equine herpesvirus type 1 (EHV-1) is a highly transmissible pathogen that leads to a variety of clinical disease outcomes in infected horses. A major sequela that can occur after an EHV-1 infection is a neurological disease termed equine herpesvirus
Externí odkaz:
https://doaj.org/article/5e42d9a05c304dc68c1490298cd3fd2c
Autor:
Manoj Chelvanambi, Matthew Powell, Connor B Cribb, Donald P. McDonnell, Rigel J. Kishton, Phat T Do, Leah L Lowder, Sridhar Varadarajan, Kelly Mastro-Kishton, Giridhar R. Akkaraju, Sean E. Miller, Libero J. Bartolotti, Suzanne E. Wardell, Charles B. Kelly, Rajeshwar Reddy Govindapur, Arthur R. Frampton
Publikováno v:
Journal of Medicinal Chemistry. 64:12651-12669
We previously described the development of a DNA-alkylating compound that showed selective toxicity in breast cancer cells. This compound contained an estrogen receptor α (ERα)-binding ligand and a DNA-binding/methylating component that could selec
Publikováno v:
Veterinary Microbiology. 192:52-59
Equine herpesvirus myeloencephalopathy (EHM), a disease caused by equine herpesvirus type 1 (EHV-1), is characterized by severe inflammation, thrombosis, and hypoxia in central nervous system (CNS) endothelial cells, which can result in a spectrum of
Autor:
Charles B. Kelly, Libero J. Bartolotti, Mairin K. Buchanan, Tyler J. Goodwin, Andrew L. McIver, Arthur R. Frampton, Maria C. White, Andrea J. Bourdelais, Lacie M. Chauvigné-Hines, Nina E. Neill, Kelly Mastro-Kishton, Sridhar Varadarajan, Chase N. Needham
Publikováno v:
Biochemistry. 56(2)
DNA-alkylating drugs continue to remain an important weapon in the arsenal against cancers. However, they typically suffer from several shortcomings because of the indiscriminate DNA damage that they cause and their inability to specifically target c
Autor:
Richard Newton, David W. Horohov, Josie L. Traub-Dargatz, Hugh G.G. Townsend, Margaret M. Brosnahan, Jules Maarten Minke, L.S. Goehring, James R. Gilkerson, D.P. Lunn, Josh Slater, Armando Damiani, C. Barnett, C. Cook, Bettina Wagner, Hans Nauwynck, Nikolaus Osterrieder, Udeni B. R. Balasuriya, G.R. Van de Walle, Julia H. Kydd, Paul S. Morley, Douglas F. Antczak, Arthur R. Frampton, G. Soboll-Hussey, Gillian A. Perkins, Lara K. Maxwell, Nicola Pusterla, Walid Azab, Debra Elton
Publikováno v:
Equine Veterinary Journal. 44:513-517
Publikováno v:
Journal of Virology. 86:2882-2886
The cytolytic animal virus equine herpesvirus type 1 (EHV-1) was evaluated for its oncolytic potential against five human glioblastoma cell lines. EHV-1 productively infected four of these cell lines, and the degree of infection was positively correl
Publikováno v:
Journal of Virology. 84:9027-9034
In this study, Equus caballus major histocompatibility complex class I (MHC-I) was identified as a cellular entry receptor for the alphaherpesvirus equine herpesvirus type 1 (EHV-1). This novel EHV-1 receptor was discovered using a cDNA library from
Autor:
Justus B. Cohen, Paola Grandi, Hiroaki Uchida, William F. Goins, Jens von Einem, Nikolaus Osterrieder, Arthur R. Frampton, Joseph C. Glorioso
Publikováno v:
Veterinary Microbiology. 141:12-21
To initiate infection, equine herpesvirus type 1 (EHV-1) attaches to heparan sulfate on cell surfaces and then interacts with a putative glycoprotein D receptor(s). After attachment, virus entry occurs either by direct fusion of the virus envelope wi
Autor:
Arthur R. Frampton, William F. Goins, Paola Grandi, Ali Ozuer, Waris A. Shah, Hiroaki Uchida, Joseph C. Glorioso, Justus B. Cohen
Publikováno v:
Journal of Virology. 83:2951-2961
Both initial infection and cell-to-cell spread by herpes simplex virus type 1 (HSV-1) require the interaction of the viral glycoprotein D (gD) with an entry receptor on the cell surface. The two major HSV entry receptors, herpesvirus entry mediator (
Autor:
Justus B. Cohen, Joseph C. Glorioso, Donna B. Stolz, Arthur R. Frampton, Hiroaki Uchida, William F. Goins
Publikováno v:
Journal of Virology. 81:10879-10889
Equine herpesvirus type 1 (EHV-1), a member of the Alphaherpesviridae , displays a broad host range in vitro, allowing for detailed study of the mechanisms of productive infection, including attachment and entry, in various cell culture systems. Prev