Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Arthur R. Buckley"'
Autor:
Peter W. Gout, Yuzhuo Wang, Sarah Mahon, Peter Dockery, Arthur R. Buckley, Jun Guan, Maisie Lo, Stephen Lam, Cristina M. Karp
Publikováno v:
Cancer Chemotherapy and Pharmacology. 64:463-472
To determine whether the xc- cystine transporter could be a useful therapeutic target for small-cell lung cancer (SCLC).Human SCLC cell cultures were examined for growth dependence on extracellular cystine, xc- expression, glutathione levels and resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069944d0c7ffda06297648d2239a5e03
https://doi.org/10.1007/s00280-008-0894-4
https://doi.org/10.1007/s00280-008-0894-4
Autor:
Donna J. Buckley, Arthur R. Buckley
Publikováno v:
Annals of the New York Academy of Sciences. 917:522-533
Evidence accumulated over the last two decades indicates important actions for prolactin (PRL) in regulation of several functions of the immune system. That PRL can serve to facilitate immune cell proliferation is well established. In addition, PRL a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa43a8c12556dec50fffe55192256b11
https://doi.org/10.1111/j.1749-6632.2000.tb05417.x
https://doi.org/10.1111/j.1749-6632.2000.tb05417.x
Autor:
Cristina M. Karp, Takeshi Kurita, Peter W. Gout, Maisie Lo, Yuzhuo Wang, Gerald R. Cunha, Hui Xue, Daniel W. Doxsee, Yuwei Wang, Jean-Claude Cutz, Arthur R. Buckley
Publikováno v:
The Prostate. 67:162-171
BACKGROUND Certain cancers depend for growth on uptake of cystine/cysteine from their environment. Here we examined advanced human prostate cancer cell lines, DU-145 and PC-3, for dependence on extracellular cystine and sensitivity to sulfasalazine (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771ca674bff72f5eda6661392f54fefd
https://doi.org/10.1002/pros.20508
https://doi.org/10.1002/pros.20508
Autor:
Basilia Zingarelli, Arthur R. Buckley, Giovanni M. Pauletti, Santosh G Dixit, Donna J. Buckley
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 288:G533-G540
Patients with refractory inflammatory bowel disease (IBD) exhibit increased expression of intestinal P-glycoprotein (P-gp) as well as elevated luminal IFN-γ and nitric oxide (NO) levels. Using the in vitro Caco-2 cell culture model, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977c7f9ba0fdc295b9181d3b373d184b
https://doi.org/10.1152/ajpgi.00248.2004
https://doi.org/10.1152/ajpgi.00248.2004
Autor:
Cherie A. Kessler, Jennifer K. Schroeder, Anoop K. Brar, Kenneth K. Moghadam, Arthur R. Buckley, Stuart Handwerger
Publikováno v:
Molecular and Cellular Endocrinology. 229:65-74
The role of cannabinoid receptor I (CBR-1) in the induction of decidualization was examined using decidual fibroblasts and human endometrial stromal cells as model systems. Decidual fibroblasts decidualized in vitro for 3 and 6 days in the presence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e914910ef4b12595e9db76da5f6f59
https://doi.org/10.1016/j.mce.2004.09.007
https://doi.org/10.1016/j.mce.2004.09.007
Autor:
Arthur R. Buckley, Donna J. Buckley, Niresh Hariparsad, Pankaj B. Desai, Rucha S. Sane, Srikanth C. Nallani
Publikováno v:
The Journal of Clinical Pharmacology. 44:1273-1281
The antiretroviral agent efavirenz enhances the systemic clearance of coadministered drugs that are cytochrome P450 (CYP) 3A4 substrates. The mechanism of the apparent increase in CYP3A4 activity by efavirenz and the magnitude of change relative to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc280a07d4e2f33d9d10b12a2b3f5ef6
https://doi.org/10.1177/0091270004269142
https://doi.org/10.1177/0091270004269142
Autor:
Jorge Isaac, William Cacini, David Sheikh-Hamad, Bellamkonda K. Kishore, Chun Chui Tsao, Arthur R. Buckley, Luan D. Truong
Publikováno v:
Archives of Toxicology. 78:147-155
Using morphological and molecular approaches, we characterized cisplatin-induced cell necrosis and apoptosis in rat kidney. Male Sprague-Dawley rats ( n=5 per group) received a single intraperitoneal injection of either cisplatin (5 mg/kg) or saline,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3dde89de37f7f36edb4854128a85046
https://doi.org/10.1007/s00204-003-0521-4
https://doi.org/10.1007/s00204-003-0521-4
Autor:
Mingyu Zhang, Huiqui Pan, Donna J. Buckley, Arthur R. Buckley, Cristina M. Karp, Linda A. Schuler
Publikováno v:
Cancer Research. 64:1016-1025
The prolactin (PRL)-dependent rat Nb2 T lymphoma is a valuable model for investigation of molecular mechanisms that underlie tumor progression in hormone-dependent cancers. mRNA differential display was used to screen for novel gene products expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66f513886c03630044fc8b0a4596baaa
https://doi.org/10.1158/0008-5472.can-03-0023
https://doi.org/10.1158/0008-5472.can-03-0023
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 308:949-956
Recent reports have documented a functional deficit of organic cation transport in diabetic rats by an unknown mechanism. This study was designed to test the hypothesis that experimental diabetes decreases expression of organic cation transporters at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8aa80bf511594cf5acc5ddc13eee617
https://doi.org/10.1124/jpet.103.058388
https://doi.org/10.1124/jpet.103.058388
Publikováno v:
Endocrinology. 144:2102-2110
The hypothesis that prolactin (PRL) functions as an immunomodulator was based on studies showing lymphocyte PRL receptors, and its effects on growth, differentiation, and apoptosis in lymphoid cells. However, studies of PRL (PRL−/−) and PRL recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f56b7cadd2d965e191add319087a05
https://doi.org/10.1210/en.2003-0053
https://doi.org/10.1210/en.2003-0053