Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Arthur Moellman-Coelho"'
Autor:
Arthur Moellman-Coelho, Ilana Zalcberg Renault, Flavia da Cunha Vasconcelos, Vivian M. Rumjanek, Andre Luiz Mencalha, Marcos Antonio Mauricio Scheiner, Raquel Ciuvalschi Maia
Publikováno v:
Leukemia research. 51
Despite the favorable clinical evolution of patients with chronic myeloid leukemia (CML), resistance or intolerance to imatinib is present in approximately 35% of patients. Sokal score is a widely used risk factor, however efflux and influx transport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5626f2c852835812afa9f81eeb4ef4
https://pubmed.ncbi.nlm.nih.gov/27770655
https://pubmed.ncbi.nlm.nih.gov/27770655
Autor:
Claudete Esteves Klumb, Maria Kadma Carriço, Franklin David Rumjanek, Ernesto de Meis, Lídia Maria Magalhães de Resende, Raquel Ciuvalschi Maia, Daniel Rodrigues Furtado, Arthur Moellman Coelho
Publikováno v:
European Journal of Haematology. 71:81-90
Objectives: The TP53 gene encodes a nuclear protein implicated in the regulation of the cell cycle, DNA repair, and apoptosis. TP53 mutations and other alterations have been described in numerous types of tumors, and some of these have been associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c74e18b6453c639af5f6a94a5128eaa6
https://doi.org/10.1034/j.1600-0609.2003.00094.x
https://doi.org/10.1034/j.1600-0609.2003.00094.x
Autor:
Flavia da Cunha Vasconcelos, Vivian M. Rumjanek, Raquel Ciuvalschi Maia, Ramza C. Harab, Arthur Moellman Coelho, Jane Dobbin
Publikováno v:
Tumor Biology. 19:41-51
Multidrug resistance in leukemic cells is associated with decreased drug accumulation. A resistant cell line and cells from 11 patients with chronic lymphoid leukemia B were used for the evaluation of intracellular accumulation of daunorubicin (DNR),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91a9fc13b37278619fae838ccbeed3c
https://doi.org/10.1159/000029973
https://doi.org/10.1159/000029973
Autor:
Flaviana Ruade de Souza Reis, Raquel Ciuvalschi Maia, KarinaL. Silva, Débora Lima Pereira, Flavia da Cunha Vasconcelos, Arthur Moellman-Coelho
Publikováno v:
Oncology reports. 26(2)
Resistance to tyrosine-kinase inhibitors is a serious problem in the treatment of chronic myeloid leukemia (CML). Using Western blot, real-time qRT-PCR and flow cytometry, we investigated the expression of survivin, Smac/DIABLO and P-glycoprotein (Pg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049212ecc8b276b8ea5e0070089a5fe6
https://pubmed.ncbi.nlm.nih.gov/21567097
https://pubmed.ncbi.nlm.nih.gov/21567097
Autor:
Alcides J. M. da Silva, Paulo R. R. Costa, Chaquip D. Netto, Luis Silva, Eduardo J. Salustiano, Débora Lima Pereira, Arthur Moellman-Coelho, Flavia da Cunha Vasconcelos, Vivian M. Rumjanek, Thiago S. Bacelar, Raquel Ciuvalschi Maia
Publikováno v:
Investigational new drugs. 29(6)
Despite the relevant therapeutic progresses obtained with imatinib, clinical resistance to this drug has emerged and reemerged after cytogenetic remission in a group of patients with chronic myeloid leukemia (CML). Therefore, novel treatment strategi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7829e57d8f74d7917cb0194a212c2179
https://pubmed.ncbi.nlm.nih.gov/20499132
https://pubmed.ncbi.nlm.nih.gov/20499132
Autor:
Karina Lani Silva, R. Linden, E. D. de Paula Castro, Arthur Moellman Coelho, Raquel Ciuvalschi Maia, Deborah Vidal Vasconcellos
Publikováno v:
Apoptosis : an international journal on programmed cell death. 11(2)
Despite the efficiency of fludarabine in the induction of clinical responses in B-cell chronic lymphocytic leukemia (B-CLL) patients, resistance to this drug has been documented. The present study tested whether resistance to fludarabine is related t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7625d2fc01537ca7c6c3f4f4ec67db6
https://pubmed.ncbi.nlm.nih.gov/16502265
https://pubmed.ncbi.nlm.nih.gov/16502265
Autor:
Claudete Esteves, Klumb, Daniel Rodrigues, Furtado, Lídia Maria Magalhães, de Resende, Maria Kadma, Carriço, Arthur Moellman, Coelho, Ernesto, de Meis, Raquel Ciuvalschi, Maia, Franklin David, Rumjanek
Publikováno v:
European journal of haematology. 71(2)
The TP53 gene encodes a nuclear protein implicated in the regulation of the cell cycle, DNA repair, and apoptosis. TP53 mutations and other alterations have been described in numerous types of tumors, and some of these have been associated with poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf939c55d3a9eeba97e6a09a7f78bcf8
https://pubmed.ncbi.nlm.nih.gov/12890146
https://pubmed.ncbi.nlm.nih.gov/12890146