Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Arthur Mazzu"'
Autor:
Arthur Mazzu, Marc Gittelman, Pavur Sundaresan, Stephen M. Auerbach, Frank Cihon, William B. White
Publikováno v:
Urology. 64:998-1003
Objectives To assess the pharmacodynamic effects of coadministered vardenafil and tamsulosin in patients with benign prostatic hyperplasia (BPH) undergoing stable tamsulosin therapy. Methods In this Phase 1, placebo-controlled, two-stage, two-way, cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17a8b96bf63a9f4850197bb98eb2323
https://doi.org/10.1016/j.urology.2004.07.038
https://doi.org/10.1016/j.urology.2004.07.038
Publikováno v:
The Journal of Clinical Pharmacology. 43:260-267
The effects of food on the pharmacokinetics of vardenafil were examined in 25 healthy adult males. Single-dose vardenafil 20 mg was administered in a randomized four-way crossover design after an overnight fast (at 8 a.m.), after consumption of a hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e098b64bdf3f9a6d6ebe347cfd0632f
https://doi.org/10.1177/0091270002250604
https://doi.org/10.1177/0091270002250604
Publikováno v:
European Journal of Clinical Pharmacology. 56:69-74
The influence of impaired renal function on the pharmacokinetics of single and multiple doses of cerivastatin was evaluated in this nonrandomized, non-blinded, 7-day, multiple-dose study.Thirty-five adults between the ages of 21 years and 75 years wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e3d59aac9e7ee76e0692a918144791
https://doi.org/10.1007/s002280050723
https://doi.org/10.1007/s002280050723
Publikováno v:
Clinical Therapeutics. 21:1563-1575
The potential mutual interaction between cerivastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, and digoxin was assessed in this nonmasked, nonrandomized, multiple-dose study. The effect of cerivastatin 0.2 mg on mean plasma digox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6cc92d318c2e455d3d933c4102fd24
https://doi.org/10.1016/s0149-2918(00)80011-9
https://doi.org/10.1016/s0149-2918(00)80011-9
Publikováno v:
Journal of the American College of Cardiology. 41(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a503a55fd5434c820a08b11c7893a623
Autor:
William M. Smith, Pavur Sundaresan, Neville Bittar, Richard A. Stein, Kenneth Pomerantz, Puneet Narayan, Robert Tota, Arthur Mazzu, Stephen D. Nash, Udho Thadani, Sharon Larkin, Stephen P. Glasser
Publikováno v:
Journal of the American College of Cardiology. 40(11)
Objectives The effect of vardenafil, a potent and highly selective phosphodiesterase-5 (PDE5) inhibitor, on symptom-limited exercise time, time to first awareness of angina, and time to ischemic threshold (ST-segment depression ≥1 mm from baseline)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbd76c1de5421619e7d3a85e5a2531f
https://pubmed.ncbi.nlm.nih.gov/12475462
https://pubmed.ncbi.nlm.nih.gov/12475462
Autor:
Arthur Mazzu, Udho Thadani
Publikováno v:
Journal of the American College of Cardiology. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4495c9414301ccf6d3e6c20fb33438
Publikováno v:
European journal of clinical pharmacology. 56(12)
The pharmacokinetics, safety, and tolerability of cerivastatin, a synthetic HMG-CoA reductase inhibitor were studied in 49 healthy volunteers. In this double-blind, parallel group, multiple-dose study, volunteers were randomized as age-matched, male-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c689d3f89ad43fd365f10f6022b2f8d
https://pubmed.ncbi.nlm.nih.gov/11317478
https://pubmed.ncbi.nlm.nih.gov/11317478
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 37(1 Suppl 2)
The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (statin)-mediated lowering of serum cholesterol has been associated with a significant reduction in cardiovascular morbidity and mortality. Recent studies suggest that additional non-lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cac62d50edc48891f826442a4237301
https://pubmed.ncbi.nlm.nih.gov/11158861
https://pubmed.ncbi.nlm.nih.gov/11158861
Autor:
John Lettieri, E. Cooper Shamblen, Kenneth C. Lasseter, Pavur Sundaresen, Arthur Mazzu, Vipin Agarwal
Publikováno v:
Clinical pharmacology and therapeutics. 68(4)
Background 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) are metabolized by distinct pathways that may alter the extent of drug-drug interactions. Cerivastatin is metabolized by cytochrome P450 (CYP)3A4 and CYP2C8. Atorvastatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5fa339ef9809565c45c7e0a7e3f876c
https://pubmed.ncbi.nlm.nih.gov/11061579
https://pubmed.ncbi.nlm.nih.gov/11061579