Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Arthur M. Melkumyants"'
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1565 (2022)
The review presents evidence that the main damage to the vascular wall occurs not from the action of “oxidized” LDL, which contain hydroperoxy acyls in the phospholipids located in their outer layer, but from the action of LDL particles whose apo
Externí odkaz:
https://doaj.org/article/c4c2fa5a152447678418cda2490dd515
Autor:
Victor Serebruany, Olga A. Antonova, Ludmila Buryachkovskaya, Arthur M. Melkumyants, Nikita Lomakin
Publikováno v:
Thrombosis and Haemostasis. 122:123-130
Background Current coronavirus disease 2019 (COVID-19) pandemic reveals thrombotic, vascular, and endothelial dysfunctions at peak disease. However, the duration, degree of damage, and appropriate long-term use of antithrombotic strategies are unclea
Autor:
Arthur M. Melkumyants, Nikita Lomakin, Vladimir V. Ermiskin, Olga A. Antonova, Liudmila Buryachkovskaya
Publikováno v:
Consilium Medicum. 23:469-476
Aim. Caused by SARS-CoV2 virus coronavirus disease (COVID-19) is characterized not only by the lung deterioration but be serious injury of vascular endothelium and system of hemostasis. We investigated changes in blood cellular elements in patients a
Publikováno v:
International Journal of Molecular Sciences. 24:128
This mini review is devoted to a specific issue: the role of malondialdehyde (MDA)—a secondary product of free radical lipid peroxidation—in the molecular mechanisms of the formation of primary atherosclerotic vascular wall lesions. The principal
Publikováno v:
Annals of Biomedical Engineering. 42:1644-1657
In many studies, the functional state of vessels of different caliber was determined by fitting the lumped parameters of a mathematical model of the bed in order to fit the vascular input impedance (Z in) data. However, reliability of the results obt
Publikováno v:
Journal of Vascular Research. 44:1-10
The effect of shear stress at the endothelium in the attenuation of the noradrenaline-induced constriction of the femoral vascular bed perfused at a constant blood flow was investigated in 16 anesthetized cats. It is known that the adrenergic vasocon
Autor:
Olga A. Antonova, Arthur M. Melkumyants, A. K. Tikhaze, Vadim Z. Lankin, Elena Kumskova, Sergey A. Balashov
Publikováno v:
Molecular and cellular biochemistry. 396(1-2)
Under some pathological conditions, the natural dicarbonyl compounds can accumulate in the blood. The examples are malonyldialdehyde (MDA) formed as a secondary product of lipid peroxidation of unsaturated fatty acids during atherosclerosis, and glyo
Publikováno v:
Fluid Dynamics. 36:48-56
On the basis of hydraulic models of the vascular bed, the possibility of quantitatively estimating the resistances, inertia coefficients and compliances of model elements, as well as the changes in these parameters, from the hydraulic input impedance
Publikováno v:
Pflügers Archiv European Journal of Physiology. 427:264-269
The lumen of arterial vessels is controlled by shear stress at the endothelium; increased shear stress relaxes the smooth muscle thus evoking arterial dilatation. Since shear stress relates directly to flow rate and inversely to the third power of th
Publikováno v:
Cardiovascular Research. 24:165-168
Experiments were designed to determine whether blood viscocity affects flow induced dilator response in conduit arteries. Changes in diameter of the femoral artery of anaesthetised cats evoked by stepwise blood flow increases were recorded at normal