Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Arthur M de Jong"'
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174682 (2017)
To gain insight into the relationship between protein structure and mechanical stability, single molecule force spectroscopy experiments on proteins with diverse structure and topology are needed. Here, we measured the mechanical stability of extende
Externí odkaz:
https://doaj.org/article/d143bbc676674d0ab9c62593e9d60f19
Autor:
Alissa D. Buskermolen, Yu-Ting Lin, Laura van Smeden, Rik B. van Haaften, Junhong Yan, Khulan Sergelen, Arthur M. de Jong, Menno W. J. Prins
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Various applications would benefit from the ability to continuously measure biomolecules. Here the authors describe a biosensing technology based on the free diffusion of biofunctionalized particles hovering over a sensor surface, which enables monit
Externí odkaz:
https://doaj.org/article/ae197fd922aa491b90fadaf826fed6dd
Autor:
Chris Vu, Yu-Ting Lin, Stijn R. R. Haenen, Julia Marschall, Annemarie Hummel, Simone F. A. Wouters, Jos M. H. Raats, Arthur M. de Jong, Junhong Yan, Menno W. J. Prins
Publikováno v:
Analytical Chemistry. 95:7950-7959
Autor:
Laura van Smeden, Annet Saris, Khulan Sergelen, Arthur M. de Jong, Junhong Yan, Menno W. J. Prins
Publikováno v:
ACS Sensors, 7(10), 3041-3048. American Chemical Society
Cortisol is a steroid hormone involved in a wide range of medical conditions. The level of the hormone fluctuates over time, but with traditional laboratory-based assays, such dynamics cannot be monitored in real time. Here, a reversible cortisol sen
Autor:
Xavier H. M. Hartmann, Peter van der Linde, Erik F. G. A. Homburg, Lambert C. A. van Breemen, Arthur M. de Jong, Regina Luttge
Publikováno v:
Pharmaceutics, Vol 7, Iss 4, Pp 503-522 (2015)
Arrays of microneedles (MNAs) are integrated in an out-of-plane fashion with a base plate and can serve as patches for the release of drugs and vaccines. We used soft-lithography and micromolding to manufacture ceramic nanoporous (np)MNAs. Failure mo
Externí odkaz:
https://doaj.org/article/576bf8729f9c48cb80d6fe3abd3784c9
Publikováno v:
ACS Sensors
ACS Sensors, 6(5), 1980-1986. American Chemical Society
ACS Sensors, 6(5), 1980-1986. American Chemical Society
Sensing technologies for the real-time monitoring of biomolecules will allow studies of dynamic changes in biological systems and the development of control strategies based on measured responses. Here, we describe a molecular architecture and coupli
Publikováno v:
Nano Letters, 20(4), 2296-2302. American Chemical Society
Nano Letters
Nano Letters
Single-molecule techniques have become impactful in bioanalytical sciences, though the advantages for continuous biosensing are yet to be discovered. Here we present a multiplexed, continuous biosensing method, enabled by an analyte-sensitive, single
Publikováno v:
ACS Sensors
ACS Sensors, 7(1), 286-295. American Chemical Society
ACS Sensors, 7(1), 286-295. American Chemical Society
Sensors for monitoring biomolecular dynamics in biological systems and biotechnological processes in real time, need to accurately and precisely reconstruct concentration–time profiles. This requirement becomes challenging when transport processes
Autor:
Fabiola A. Gutiérrez-Mejía, Nicolò Alvisi, Meike Lokker, Floris L. van Delft, Yu Ting Lin, Renko de Vries, Arthur M. de Jong
Publikováno v:
Biomacromolecules
Biomacromolecules, 22(5), 1966-1979. American Chemical Society
Biomacromolecules 22 (2021) 5
Biomacromolecules, 22(5), 1966-1979
Biomacromolecules, 22(5), 1966-1979. American Chemical Society
Biomacromolecules 22 (2021) 5
Biomacromolecules, 22(5), 1966-1979
Control over the placement and activity of biomolecules on solid surfaces is a key challenge in bionanotechnology. While covalent approaches excel in performance, physical attachment approaches excel in ease of processing, which is equally important
Publikováno v:
ACS Nano, 15(1). American Chemical Society
ACS Nano
ACS Nano
The biofunctionalization of particles with specific targeting moieties forms the foundation for molecular recognition in biomedical applications such as targeted nanomedicine and particle-based biosensing. To achieve a high precision of targeting for