Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Arthur M Mercurio"'
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 8, Pp n/a-n/a (2021)
Abstract Understanding how cancer cells resist ferroptosis is a significant problem that impacts ongoing efforts to stimulate ferroptosis as a therapeutic strategy. We reported that prominin2 is induced by ferroptotic stimuli and functions to resist
Externí odkaz:
https://doaj.org/article/4aedcb591f994074b7cbad438400d477
Autor:
Rajarshi Ghosh, Kathryn L Lipson, Karen E Sargent, Arthur M Mercurio, Joan S Hunt, David Ron, Fumihiko Urano
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9575 (2010)
Angiogenesis is crucial to many physiological and pathological processes including development and cancer cell survival. Vascular endothelial growth factor-A (VEGFA) is the predominant mediator of angiogenesis in the VEGF family. During development,
Externí odkaz:
https://doaj.org/article/8fdbad546e3e47adb70f5a55aa59062d
Autor:
Dimpi Mukhopadhyay, Hira Lal Goel, Choua Xiong, Shivam Goel, Ayush Kumar, Rui Li, Lihua Julie Zhu, Jennifer L. Clark, Michael A. Brehm, Arthur M. Mercurio
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113347- (2023)
Summary: Understanding the cell biological mechanisms that enable tumor cells to persist after therapy is necessary to improve the treatment of recurrent disease. Here, we demonstrate that transient receptor potential channel 6 (TRPC6), a channel tha
Externí odkaz:
https://doaj.org/article/7444b6fcbf5240869afc18f3d3cac501
Autor:
Caitlin W. Brown, Arthur M. Mercurio
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 3 (2020)
Understanding how cells resist ferroptosis is necessary for exploiting this iron-dependent mode of cell death for the treatment of cancer and other diseases. We discovered that cells resist ferroptosis by enabling a PROMININ2-dependent iron export pa
Externí odkaz:
https://doaj.org/article/0d7c52d073664b1c9a3c502a53178346
Autor:
Ulla M. Wewer, Arthur M. Mercurio, Atsuko Sehara-Fujisawa, Marie Kveiborg, Pauliina Kronqvist, Reidar Albrechtsen, Camilla Nehammer, Camilla Fröhlich
PDF file - 300K, ADAM12 immunolocalization in a subcutanous Lewis Lung tumor. Immunohistochemical staining of ADAM12 in Lewis Lung tumors grown for 15 days in ADAM12+/- mice using A) 2�g/mL affinity purified ADAM12 polyclonal antibody from ProteinT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c1e3f51bec46df011d510835e2645b
https://doi.org/10.1158/1541-7786.22518852
https://doi.org/10.1158/1541-7786.22518852
Autor:
Ulla M. Wewer, Arthur M. Mercurio, Atsuko Sehara-Fujisawa, Marie Kveiborg, Pauliina Kronqvist, Reidar Albrechtsen, Camilla Nehammer, Camilla Fröhlich
PDF file - 213K, A Pan-cytokeratin expression (green) in immortalized PyMT-A12hz and PyMT-A12null tumor cells. Blue represents DAPI staining. Bar = 12 �m. B. Mean (�SD) total tumor burden on FVB/N mice injected subcutaneously in the right flank w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53943fe2f36fc002b5b6dfd9eb90e5f2
https://doi.org/10.1158/1541-7786.22518861.v1
https://doi.org/10.1158/1541-7786.22518861.v1
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 819K, List of primer sequences for semi-quantitative and quantitative PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf73393db3013b6384478cc00eef3b5c
https://doi.org/10.1158/2159-8290.22528323
https://doi.org/10.1158/2159-8290.22528323
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 504K, Response of xenografts of human prostate cancer specimens to IGF-1R inhibition as a function of NRP2 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295edcca33a65a6ce1108ff9fdef3db9
https://doi.org/10.1158/2159-8290.22528326.v1
https://doi.org/10.1158/2159-8290.22528326.v1
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 454K, Role of JNK/c-Jun in regulating NRP2 expression in prostate carcinoma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efccae0f6307b050a11fd5c4d33e409
https://doi.org/10.1158/2159-8290.22528335
https://doi.org/10.1158/2159-8290.22528335
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 1.8MB, Evaluation of insulin signaling in prostate tumors and cell lines as a function of NRP2 expression and role of VEGF in regulation of Bmi-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234d2f155ca4325ac0e5289d5af835d8
https://doi.org/10.1158/2159-8290.22528329.v1
https://doi.org/10.1158/2159-8290.22528329.v1