Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Arthur M Buchberg"'
A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer.
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23665 (2011)
Colorectal cancer is one of the most common cancers in developed nations and is the result of both environmental and genetic factors. Many of the genetic lesions observed in colorectal cancer alter expression of homeobox genes, which encode homeodoma
Externí odkaz:
https://doaj.org/article/803d086f7c76496393c5a2e63b1adc10
Autor:
Leonard P. Freedman, Mark C. Gibson, Andrew R.M. Bradbury, Arthur M. Buchberg, Darryl Davis, Marisa P. Dolled-Filhart, Fridtjof Lund-Johansen, David L. Rimm
Publikováno v:
BioTechniques, Vol 61, Iss 1, Pp 16-18 (2016)
Externí odkaz:
https://doaj.org/article/6caa14e97015426ab426fc8801c9cdd7
Autor:
Mark C Gibson, Fridtjof Lund-Johansen, Marisa Dolled-Filhart, Arthur M. Buchberg, Darryl Davis, Leonard P. Freedman, Andrew Bradbury, David L. Rimm
Publikováno v:
BioTechniques. 61:16-18
Address correspondence to Leonard P. Freedman, Global Biological Standards Institute, 1020 19th Street, NW, Suite 550, Washington, DC, 20036. E-mail: lfreedman@gbsi.org.
Identification of five novel modifier loci of ApcMin harbored in the BXH14 recombinant inbred strain
Autor:
Julie Innocent, Rayneisha Watson, Stephanie C. Nnadi, Arthur M. Buchberg, Gregory E. Gonye, Linda D. Siracusa
Publikováno v:
Carcinogenesis. 33:1589-1597
Every year thousands of people in the USA are diagnosed with small intestine and colorectal cancers (CRC). Although environmental factors affect disease etiology, uncovering underlying genetic factors is imperative for risk assessment and developing
Autor:
Richard C. Crist, Michael P. Lisanti, Arthur M. Buchberg, Linda D. Siracusa, Jacquelyn J. Roth
Publikováno v:
Cell Cycle. 10:1092-1099
Colorectal cancer is a heterogeneous disease resulting from a combination of genetic and environmental factors. The C57BL/6J (B6) Apc (Min/+) mouse develops polyps throughout the gastrointestinal tract and has been a valuable model for understanding
Autor:
Tao Zhang, Zenobia Cofer, Jeremy Z. Fields, Arthur M. Buchberg, Linda D. Siracusa, Tomas Otevrel, Bruce M. Boman, Levy Kopelovich, Kim Henderson
Publikováno v:
Molecular Carcinogenesis. 48:821-831
Apc mutations cause intestinal tumorigenesis through Tcf4 activation. However, direct techniques for studying Tcf4 activation in vivo are limited. Here, we describe the development of a Tcf4-GFP reporter mouse model for directly studying Tcf4 activat
Autor:
Arthur M. Buchberg, Linda D. Siracusa
Publikováno v:
Mammalian Genome. 19:449-453
Imagine you are playing a piano. Your fingers sequentially move from one end of the keyboard to the other. Now imagine there is another person, playing the same keys in the opposite direction. Add yet another set of hands, which start and stop playin
Publikováno v:
Mammalian Genome. 17:808-821
The myeloid progenitor cell compartment (MPC) exhibits pronounced expansion in human myeloid leukemias. It is becoming more apparent that progression of myelodysplastic syndromes and myeloproliferative diseases to acute myelogenous leukemia is the re
Autor:
Linda D. Siracusa, Revati Koratkar, Karen A. Silverman, Arthur M. Buchberg, Rhonda Walters, Melina Macphee-Pellini, Vincent E. Sollars, Steven A. Farber, Marina Markova, Juan P. Palazzo
Publikováno v:
Oncogene. 24:6450-6458
The secreted phospholipase A2 type IIA (Pla2g2a) gene was previously identified as a modifier of intestinal adenoma multiplicity in Apc Min/+ mice. To determine if intestinal secreted phospholipase A2 (sPLA2) activity was also attenuated in susceptib
Autor:
Peter J. Wermuth, Arthur M. Buchberg
Publikováno v:
Blood. 105:1222-1230
Coexpression of the homeodomain protein Meis1 and either HoxA7 or HoxA9 is characteristic of many acute myelogenous leukemias. Although Meis1 can be overexpressed in bone marrow long-term repopulating cells, it is incapable of mediating their transfo