The globus pallidus orchestrates abnormal network dynamics in a model of Parkinsonism

Autor: Brice de la Crompe, Asier Aristieta, Arthur Leblois, Salma Elsherbiny, Thomas Boraud, Nicolas P. Mallet

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

Oscillatory changes between basal ganglia nuclei occur in Parkinson’s disease. Here the authors determine that the globus pallidus is the source of beta oscillation generation in a rodent model of the disease.

Externí odkaz: https://doaj.org/article/76e9de8e966344ba8ede1b7a7bab2a16

Striatal Cholinergic Interneurons: How to Elucidate Their Function in Health and Disease

Autor: Nicolas Mallet, Arthur Leblois, Nicolas Maurice, Corinne Beurrier

Publikováno v: Frontiers in Pharmacology, Vol 10 (2019)

Striatal cholinergic interneurons (CINs) are the main source of acetylcholine in the striatum and are believed to play an important role in basal ganglia physiology and pathophysiology. The role of CINs in striatal function is known mostly from extra

Externí odkaz: https://doaj.org/article/735500224b6d418fa310e65248e5239c

A subcortical circuit linking the cerebellum to the basal ganglia engaged in vocal learning

Autor: Ludivine Pidoux, Pascale Le Blanc, Carole Levenes, Arthur Leblois

Publikováno v: eLife, Vol 7 (2018)

Speech is a complex sensorimotor skill, and vocal learning involves both the basal ganglia and the cerebellum. These subcortical structures interact indirectly through their respective loops with thalamo-cortical and brainstem networks, and directly

Externí odkaz: https://doaj.org/article/bf0340dda943484eb9a74607e222734b

Interference and shaping in sensorimotor adaptations with rewards.

Autor: Ran Darshan, Arthur Leblois, David Hansel

Publikováno v: PLoS Computational Biology, Vol 10, Iss 1, p e1003377 (2014)

When a perturbation is applied in a sensorimotor transformation task, subjects can adapt and maintain performance by either relying on sensory feedback, or, in the absence of such feedback, on information provided by rewards. For example, in a classi

Externí odkaz: https://doaj.org/article/dcc9c2881efa477da60fe389d7c967a4

Computational benefits of structural plasticity, illustrated in songbirds

Autor: Remya Sankar, Arthur Leblois, Nicolas P. Rougier

Publikováno v: Neuroscience and Biobehavioral Reviews
Neuroscience and Biobehavioral Reviews, inPress, 132, pp.1183-1196. ⟨10.1016/j.neubiorev.2021.10.033⟩
Neuroscience & Biobehavioral Reviews
Neuroscience & Biobehavioral Reviews, Oxford: Elsevier Ltd., In press

International audience; The plasticity of nervous systems allows animals to quickly adapt to a changing environment. In particular, the structural plasticity of brain networks is o en critical to the development of the central nervous system and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122896d454c6b6977fa63888d5781479
https://doi.org/10.1016/j.neubiorev.2021.10.033