Výsledky vyhledávání - "Arthur Kammeyer"

Natural moisturizing factor components in the stratum corneum as biomarkers of filaggrin genotype: evaluation of minimally invasive methods

Autor: Arthur Kammeyer, Sanja Kezic, Jan D. Bos, Florentine Calkoen, Joachim W. Fluhr

Publikováno v: British journal of dermatology, 161(5), 1098-1104. Wiley-Blackwell

Summary Background The carriers of loss-of-function mutations in the filaggrin gene (FLG) have reduced levels of natural moisturizing factor (NMF) in the stratum corneum. The concentration of NMF components which are formed by filaggrin protein break

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88163c896b956a45d5c6e4ab436d63ce
https://doi.org/10.1111/j.1365-2133.2009.09342.x

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Postelicitation model of allergic contact dermatitis for predicting the efficacy of topical drugs

Autor: Jan D. Bos, Marcel B. M. Teunissen, Arthur Kammeyer

Publikováno v: Experimental dermatology, 18(1), 44-49. Wiley-Blackwell

To evaluate the anti-inflammatory efficacies of topical drugs, models of contact hypersensitivity (CHS) can be used, but the conventional murine models of CHS need revision in this respect. These models utilize sensitized mice to study suppression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b77cab3b9f26d0687ba812a94093b2
https://doi.org/10.1111/j.1600-0625.2008.00757.x

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Suppression of Different Phases of Systemic Contact Hypersensitivity by Urocanic Acid Oxidation Productsfn1

Autor: Arthur Kammeyer, Johan Garssen, Annemarie Sleijffers, Henk Loveren, Teunis A. Eggelte, Jan D. Bos, Marcel B. M. Teunissen

Publikováno v: Photochemistry and Photobiology. 80:72-77

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63b2f26dc84133a4c021fad4a30ca6cf
https://doi.org/10.1111/j.1751-1097.2004.tb00051.x

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Oxidative breakdown and conversion of urocanic acid isomers by hydroxyl radical generating systems

Autor: Marcel B. M. Teunissen, Albert H. Bootsma, H. Overmars, Arthur Kammeyer, Jan D. Bos, Teunis A. Eggelte

Publikováno v: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1526(3), 277-285. Elsevier

cis-Urocanic acid (cis-UCA), formed from trans-urocanic acid (trans-UCA) by photoisomerization, has been shown to mimic suppressive effects of UV on the immune system. It is our hypothesis that UCA oxidation products in the skin play a role in the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016a2b325f27e3a957504c0ef924b37a
https://doi.org/10.1016/s0304-4165(01)00139-8

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Urocanic acid isomers are good hydroxyl radical scavengers: a comparative study with structural analogues and with uric acid

Autor: Arthur Kammeyer, Teunis A. Eggelte, Marcel B. M. Teunissen, Jan D. Bos

Publikováno v: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1428(1), 117-120. Elsevier

UV-exposure of the epidermis leads to the isomerisation of trans-UCA into cis-UCA as well as to the generation of hydroxyl radicals. This study shows by means of the deoxyribose degradation test that UCA isomers are more powerful hydroxyl radical sca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05dccdcf742c0de8e14a5076634da32
https://doi.org/10.1016/s0304-4165(99)00063-x

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Evaluation of an HPLC Method for the determination of natural moisturizing factors in the human stratum corneum

Autor: Nico L. H. Yau, Irena Dapic, Sanja Kezic, Arthur Kammeyer, Ivone Jakasa

Publikováno v: ANALYTICAL LETTERS, 46(14), 2133-2144. Taylor and Francis Ltd.

The levels of natural moisturizing factors in the skin can be used as a biomarker of hydration, for studying the effect of skin irritants, or as a biomarker of loss-of-function mutations in the filaggrin gene which are the main risk factor for atopic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210c1ad1e4319bc6fa45d022caaa1e3c
https://doi.org/10.1080/00032719.2013.789881

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Increased Sensitivity of Histidinemic Mice to UVB Radiation Suggests a Crucial Role of Endogenous Urocanic Acid in Photoprotection

Autor: Minoo Ghannadan, Sanja Kezic, Katja Posa-Markaryan, Erwin Tschachler, Arthur Kammeyer, Caterina Barresi, Caroline Stremnitzer, Veronika Mlitz, Clare Selden, Leopold Eckhart

Publikováno v: Journal of investigative dermatology, 131(1), 188-194. Nature Publishing Group

Urocanic acid (UCA) is produced by the enzyme histidase and accumulates in the stratum corneum of the epidermis. In this study, we investigated the photoprotective role of endogenous UCA in the murine skin using histidinemic mice, in which the gene e

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https://pure.amc.nl/en/publications/increased-sensitivity-of-histidinemic-mice-to-uvb-radiation-suggests-a-crucial-role-of-endogenous-urocanic-acid-in-photoprotection(dde74880-ad66-411c-89dd-6b010f45cc4c).html

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The Relation Between Constitutional Skin Color and Photosensitivity Estimated from UV-Induced Erythema and Pigmentation Dose-Response Curves

Autor: Arthur Kammeyer, Muriel Durocq, Wiete Westerhof, Joes Meens, Oscar Estevez-Uscanga, Irina Cario

Publikováno v: Journal of investigative dermatology, 94(6), 812-816. Nature Publishing Group

In 54 healthy volunteers we assessed predictors of sensitivity to ultraviolet (UV) light, including Fitzpatrick's sun reactive skin types and constitutional skin color, and compared these with one another and with responses of the skin to UV irradiat

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