Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Arthur J Van De Vyver"'
Autor:
Arthur J. Van De Vyver, Antje-Christine Walz, Mariette S. Heins, Afsaneh Abdolzade-Bavil, Thomas E. Kraft, Inja Waldhauer, Michael B. Otteneder
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Monoclonal antibodies play an important role in the treatment of various diseases. However, the development of these drugs against neurological disorders where the drug target is located in the brain is challenging and requires a good understanding o
Externí odkaz:
https://doaj.org/article/3178277d91194c33ad0c97715f1819eb
Autor:
Antje-Christine Walz, Marina Bacac, Thorsten Lehr, Florian Limani, Sarah Diggelmann, Jitka Somandin, Regula B. Buser, Sylvia Herter, Nicolas Frances, Miro J. Eigenmann, Tina Weinzierl, Arthur J. Van De Vyver
Experimental data triplicate values with model fit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236fc9f6a87241f542cdff136010e359
https://doi.org/10.1158/1535-7163.22521570.v1
https://doi.org/10.1158/1535-7163.22521570.v1
Autor:
Antje-Christine Walz, Marina Bacac, Thorsten Lehr, Florian Limani, Sarah Diggelmann, Jitka Somandin, Regula B. Buser, Sylvia Herter, Nicolas Frances, Miro J. Eigenmann, Tina Weinzierl, Arthur J. Van De Vyver
Targeted T-cell redirection is a promising field in cancer immunotherapy. T-cell bispecific antibodies (TCB) are novel antibody constructs capable of binding simultaneously to T cells and tumor cells, allowing cross-linking and the formation of immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660357c498b0b8984076522718e1e498
https://doi.org/10.1158/1535-7163.c.6543060
https://doi.org/10.1158/1535-7163.c.6543060
Autor:
Antje-Christine Walz, Marina Bacac, Thorsten Lehr, Florian Limani, Sarah Diggelmann, Jitka Somandin, Regula B. Buser, Sylvia Herter, Nicolas Frances, Miro J. Eigenmann, Tina Weinzierl, Arthur J. Van De Vyver
Estimated parameter values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ceb060b2ec8eb42fe870e1ca310382
https://doi.org/10.1158/1535-7163.22521552.v1
https://doi.org/10.1158/1535-7163.22521552.v1
Autor:
Antje-Christine Walz, Marina Bacac, Thorsten Lehr, Florian Limani, Sarah Diggelmann, Jitka Somandin, Regula B. Buser, Sylvia Herter, Nicolas Frances, Miro J. Eigenmann, Tina Weinzierl, Arthur J. Van De Vyver
Supplementary section S1 describes the compound properties of cibisatamab as well as details on data generation, model development and modeling strategy applied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce5d10b23066566fc8b27cf6312e8fe
https://doi.org/10.1158/1535-7163.22521558
https://doi.org/10.1158/1535-7163.22521558
Cytokine Release Syndrome By T-cell–Redirecting Therapies: Can We Predict and Modulate Patient Risk?
Publikováno v:
Clinical Cancer Research. 27:6083-6094
T-cell–redirecting therapies are promising new therapeutic options in the field of cancer immunotherapy, but the development of these modalities is challenging. A commonly observed adverse event in patients treated with T-cell–redirecting therapi
Autor:
Florian Limani, Tina Weinzierl, Arthur J Van De Vyver, Marina Bacac, Thorsten Lehr, Nicolas Frances, Sarah Diggelmann, Miro J. Eigenmann, Regula B. Buser, Sylvia Herter, Antje-Christine Walz, Jitka Somandin
Publikováno v:
Molecular Cancer Therapeutics. 20:357-366
Targeted T-cell redirection is a promising field in cancer immunotherapy. T-cell bispecific antibodies (TCB) are novel antibody constructs capable of binding simultaneously to T cells and tumor cells, allowing cross-linking and the formation of immun
Autor:
Antje-Christine Walz, Arthur J. Van De Vyver, Li Yu, Marc R. Birtwistle, Nevan J. Krogan, Mehdi Bouhaddou
Publikováno v:
Pharmacol Ther
Dysregulated epigenetic processes can lead to altered gene expression and give rise to malignant transformation and tumorigenesis. Epigenetic drugs aim to revert the phenotype of cancer cells to normally functioning cells, and are developed and appli
Autor:
Thorsten Lehr, Christian Klein, Sylvia Herter, Tanja Fauti, Meric A. Ovacik, Miro J. Eigenmann, Marina Bacac, Tina Weinzierl, Arthur J Van De Vyver, Christian Pohl, Antje-Christine Walz
Publikováno v:
The AAPS journal. 24(1)
CD3-bispecific antibodies are a new class of immunotherapeutic drugs against cancer. The pharmacological activity of CD3-bispecifics is typically assessed through in vitro assays of cancer cell lines co-cultured with human peripheral blood mononuclea
Autor:
Arthur J, Van De Vyver, Tina, Weinzierl, Miro J, Eigenmann, Nicolas, Frances, Sylvia, Herter, Regula B, Buser, Jitka, Somandin, Sarah, Diggelmann, Florian, Limani, Thorsten, Lehr, Marina, Bacac, Antje-Christine, Walz
Publikováno v:
Molecular cancer therapeutics. 20(2)
Targeted T-cell redirection is a promising field in cancer immunotherapy. T-cell bispecific antibodies (TCB) are novel antibody constructs capable of binding simultaneously to T cells and tumor cells, allowing cross-linking and the formation of immun