Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Arthur Hawtrey"'
Publikováno v:
South African Journal of Science, Vol 106, Iss 7/8 (2010)
Moloney murine leukaemia virus (M-MuLV) is a member of the retrovirus family. Its cloned reverse transcriptase (RT), similarly to HIV type 1 reverse transcriptase (HIV-1 RT), exhibits DNA-polymerase and ribonuclease H (RNase H) activities capable of
Externí odkaz:
https://doaj.org/article/74b4ac7a1e20497b9fbb92e4baab511a
Publikováno v:
Drug Delivery. 17:426-433
The asialoglycoprotein receptor, which is abundantly and near exclusively expressed on hepatocytes, has received much attention in the design of non-viral hepatotropic DNA delivery systems. Thus, asialoglycoproteins and hexopyranosyl ligands have bee
Publikováno v:
International Journal of Pharmaceutics. 321:124-137
Novel transfecting assemblies comprising biotinylated cationic liposomes, DNA and tribiotinylated transferrin-streptavidin (streptavidin(bio 3 -transferrin)) accessories have been prepared, characterized and evaluated for toxicity and DNA delivery ca
Publikováno v:
Drug Delivery. 4:115-119
Modification of streptavidin (biotinylated transferrin)-biotinylated polylysine conjugates for DNA delivery by covalent addition of polyethylene glycol chains was investigated. It was found that ad...
Publikováno v:
Drug Design, Development and Therapy
Johann M van Zyl,1 Johan Smith,2 Arthur Hawtrey1 1Division of Pharmacology, 2Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa Background: Currently, a new generation of synthetic pulmonary surfactants is be
Publikováno v:
South African Journal of Science, Volume: 106, Issue: 7-8, Pages: 1-5, Published: AUG 2010
South African Journal of Science, Vol 106, Iss 7/8 (2010)
South African Journal of Science, Vol 106, Iss 7/8 (2010)
Moloney murine leukaemia virus (M-MuLV) is a member of the retrovirus family. Its cloned reverse transcriptase (RT), similarly to HIV type 1 reverse transcriptase (HIV-1 RT), exhibits DNA-polymerase and ribonuclease H (RNase H) activities capable of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fabb1679710e8b01baad9943f067e0c8
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0038-23532010000400016&lng=en&tlng=en
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0038-23532010000400016&lng=en&tlng=en
Autor:
Mario Ariatti, Marichen Van der Merwe, Pieter van der Bijl, William Nel, Anton Pieterse, Johann M. van Zyl, Arthur Hawtrey
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 27(9)
N-Acylated derivatives of 8-(6-aminohexyl) amino-adenosine-5 '-phosphate were prepared and studied with regard to their effect on DNA synthesis by the Moloney leukemia virus reverse transcriptase. N-palmitoyl and N-nicotinyl derivatives and bis-8-(6-
Publikováno v:
Biochemical Pharmacology. 40:253-263
Evidence is presented for targeted gene delivery to HepG2 cells via the endocytotic pathway under the direction of insulin. Serum albumin was treated with the water-soluble carbodiimide N -ethyl- N ′-(3-dimethylaminopropyl) carbodiimide hydrochlori
Autor:
Pieter van der Bijl, Gwynnèth Quick, Johann M. van Zyl, Arthur Hawtrey, Anton Pieterse, Gretchen Larson
Publikováno v:
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. 18(3)
The binding and encapsulation of [3H] pGL3 luciferase reporter plasmid DNA by red blood cell (RBC) ghosts, intended as a vehicle for transfection and ultimately for gene therapy, were studied using two methods for DNA compaction.In the first approach
Publikováno v:
Drug delivery. 10(3)
Low density lipoproteins (LDL) have been cationized using the water-soluble carbodiimide, N-ethyl-N'-(3-trimethylpropylammonium) carbodiimide iodide at a reagent: lipoprotein mole ratio of 10 000:1. This was shown to increase the innate DNA-binding c