Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Arthur H A M, van Onzen"'
Autor:
Raffaella Rossin, Ron M. Versteegen, Jeremy Wu, Alisher Khasanov, Hans J. Wessels, Erik J. Steenbergen, Wolter ten Hoeve, Henk M. Janssen, Arthur H. A. M. van Onzen, Peter J. Hudson, Marc S. Robillard
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Current antibody-drug conjugates (ADCs) target internalising receptors on cancer cells. Here, the authors report the development and in vivo validation of a non-internalising ADC with the capacity to target cancer cells and release its therapeutic ca
Externí odkaz:
https://doaj.org/article/b6e9e26c80024b1e84795b448f5f9b65
Autor:
Raffaella Rossin, Ron M. Versteegen, Jeremy Wu, Alisher Khasanov, Hans J. Wessels, Erik J. Steenbergen, Wolter ten Hoeve, Henk M. Janssen, Arthur H. A. M. van Onzen, Peter J. Hudson, Marc S. Robillard
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article omitted the following from the Acknowledgements: ‘This work was supported by the Office of the Assistant Secretary of Defense for Health Affairs, through the Breast Cancer Research Program under Award No. W81XWH
Externí odkaz:
https://doaj.org/article/fea92d6bbdb8481183adf2d4a9442582
Autor:
Jeremy Wu, Henk M. Janssen, Marc S. Robillard, Wolter ten Hoeve, Raffaella Rossin, Ivo A. W. Filot, Freek J. M. Hoeben, Tong Zhu, Ron M. Versteegen, Arthur H. A. M. van Onzen, Peter J. Hudson
Publikováno v:
Journal of the American Chemical Society, 142(25), 10955-10963. American Chemical Society
The high reaction rate of the 'click-to-release' reaction between allylic substituted trans-cyclooctene and tetrazine has enabled exceptional control over chemical and biological processes. Here we report the development of a new bioorthogonal cleava
Publikováno v:
ChemBioChem, 19(23), 2490-2494. Wiley-VCH Verlag
Chembiochem
Chembiochem
Caspase‐8 constructs featuring an N‐terminal FGG sequence allow for selective twofold recognition by cucurbit[8]uril, which leads to an increase of the enzymatic activity in a cucurbit[8]uril dose‐dependent manner. This supramolecular switching
Autor:
Arthur H A M, van Onzen, Ron M, Versteegen, Freek J M, Hoeben, Ivo A W, Filot, Raffaella, Rossin, Tong, Zhu, Jeremy, Wu, Peter J, Hudson, Henk M, Janssen, Wolter, Ten Hoeve, Marc S, Robillard
Publikováno v:
Journal of the American Chemical Society. 142(25)
The high rate of the 'click-to-release' reaction between an allylic substituted
Autor:
Klaas Nicolay, Arthur H. A. M. van Onzen, Marc Stefan Robillard, Lech-Gustav Milroy, Luc Brunsveld, Albertus P. H. J. Schenning, Raffaella Rossin
Publikováno v:
Bioconjugate Chemistry, 30(3). American Chemical Society
Bioconjugate Chemistry
Bioconjugate Chemistry
Multimodal imaging agents combine two or more imaging modalities into one probe. Self-assembling fluorescent nanoparticles are a promising class of modular multimodal imaging probes as they can allow easy blending of imaging and targeting modalities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f67c85a68a5e366784d346545aca55
https://research.tue.nl/nl/publications/ef6242bc-0074-4ca1-a074-f5541c4b4027
https://research.tue.nl/nl/publications/ef6242bc-0074-4ca1-a074-f5541c4b4027
Autor:
Barbara Gräfen, Stefan Kramer, Sascha Schmitt, Lydia Braun, Kaloian Koynov, Dennis Svatunek, Raffaella Rossin, Arthur H. A. M. van Onzen, Irina Alberg, Hannes Mikula, Rudolf Zentel
Publikováno v:
Biomacromolecules, 20, 3786-3797
Biomacromolecules, 20, 10, pp. 3786-3797
Biomacromolecules
Biomacromolecules, 20, 10, pp. 3786-3797
Biomacromolecules
Contains fulltext : 216143.pdf (Publisher’s version ) (Open Access) Fast and bioorthogonally reacting nanoparticles are attractive tools for biomedical applications such as tumor pretargeting. In this study, we designed an amphiphilic block copolym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd97613d3205f3cbe885598cc08ce151
http://hdl.handle.net/2066/216143
http://hdl.handle.net/2066/216143
Autor:
Jeremy Wu, Alisher Khasanov, Peter J. Hudson, Ron M. Versteegen, Wolter ten Hoeve, Henk M. Janssen, Raffaella Rossin, Arthur H. A. M. van Onzen, Erik J. Steenbergen, Marc S. Robillard, Hans J. C. T. Wessels
Publikováno v:
Nature Communications, 9(1):1484. Nature Publishing Group
Nature Communications, 9, pp.
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications, 9,
Nature Communications
Nature Communications, 9, pp.
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications, 9,
Nature Communications
Current antibody-drug conjugates (ADCs) target internalising receptors on cancer cells leading to intracellular drug release. Typically, only a subset of patients with solid tumours has sufficient expression of such a receptor, while there are suitab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77b0775e4d21e2277afc8b9588b3e4a
https://research.tue.nl/nl/publications/e37d6b6f-65df-4929-8563-a399982085ef
https://research.tue.nl/nl/publications/e37d6b6f-65df-4929-8563-a399982085ef
Autor:
Lorenzo Albertazzi, Lech-Gustav Milroy, Arthur H. A. M. van Onzen, Albertus P. H. J. Schenning, Luc Brunsveld
Publikováno v:
Chemical Communications, ChemComm, 53(10), 1626-1629. Royal Society of Chemistry
The fate of small molecule nanoparticles (SMNPs) composed of self-assembling intrinsically fluorescent π-conjugated oligomers was studied in cells as a function of side-chain hydrophobicity. While the hydrophobic SMNPs remained intact upon cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39089cacfed499ddba238167a4b8d2b2
https://research.tue.nl/nl/publications/6d372bca-b506-48e0-bfb8-578280f3ab4c
https://research.tue.nl/nl/publications/6d372bca-b506-48e0-bfb8-578280f3ab4c
Autor:
Hans J. C. T. Wessels, Henk M. Janssen, Alisher Khasanov, Erik J. Steenbergen, Marc S. Robillard, Ron M. Versteegen, Jeremy Wu, Wolter ten Hoeve, Raffaella Rossin, Peter J. Hudson, Arthur H. A. M. van Onzen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article omitted the following from the Acknowledgements: ‘This work was supported by the Office of the Assistant Secretary of Defense for Health Affairs, through the Breast Cancer Research Program under Award No. W81XWH