Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Arthur Fridman"'
Autor:
Julie M. Strizki, Jay A. Grobler, Nicholas Murgolo, Arthur Fridman, Matthew G. Johnson, Jiejun Du, Patricia Carmelitano, Michelle L. Brown, Amanda Paschke, Carisa De Anda
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 12, Pp 2725-2743 (2023)
Abstract Introduction The randomized, placebo-controlled, double-blind MOVe-OUT trial demonstrated molnupiravir (800 mg every 12 h for 5 days) as safe and effective for outpatient treatment of mild-to-moderate COVID-19, significantly reducing the ris
Externí odkaz:
https://doaj.org/article/d0521e225c0440b48f259f56e15c4d93
Autor:
Scott A. Hollingsworth, Cameron L. Noland, Karin Vroom, Anasuya Saha, Miranda Sam, Qinshan Gao, Haihong Zhou, David U. Grandy, Sujata Singh, Zhiyun Wen, Christopher Warren, Xiaohong Shirley Ma, Daniel Malashock, Jennifer Galli, Gwenny Go, Michael Eddins, Todd Mayhood, Karthik Sathiyamoorthy, Arthur Fridman, Fahimeh Raoufi, Yacob Gomez-Llorente, Andrea Patridge, Yinyan Tang, Shi-Juan Chen, Marc Bailly, Chengjie Ji, Laura J. Kingsley, Alan C. Cheng, Bernhard H. Geierstanger, Daniel M. Gorman, Lan Zhang, Kalyan Pande
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Coronaviruses have been the causative agent of three epidemics and pandemics in the past two decades, including the ongoing COVID-19 pandemic. A broadly-neutralizing coronavirus therapeutic is desirable not only to prevent and treat COVID-19
Externí odkaz:
https://doaj.org/article/a9d7ab42a9cb4a6cb05bac47eef92301
Autor:
Julie M. Strizki, Jay A. Grobler, Nicholas Murgolo, Arthur Fridman, Matthew G. Johnson, Jiejun Du, Patricia Carmelitano, Michelle L. Brown, Amanda Paschke, Carisa De Anda
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 5, Pp 1159-1160 (2024)
Externí odkaz:
https://doaj.org/article/88e4092f879442818c11a0939d8d1d66
Autor:
Xiao Xiao, Arthur Fridman, Lu Zhang, Pavlo Pristatsky, Eberhard Durr, Michael Minnier, Aimin Tang, Kara S. Cox, Zhiyun Wen, Renee Moore, Dongrui Tian, Jennifer D. Galli, Scott Cosmi, Michael J. Eddins, Nicole L. Sullivan, Xiaodong Yan, Andrew J. Bett, Hua-Poo Su, Kalpit A. Vora, Zhifeng Chen, Lan Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Here, Xiao et al. isolate a large panel of antibodies against human metapneumovirus fusion protein from human B cells, and characterize their epitopes, neutralization activities, and antigen binding specificity, providing a useful framework for under
Externí odkaz:
https://doaj.org/article/39a413c0e00f4ee69f63888b87fa5809
Autor:
Luigi Aurisicchio, Arthur Fridman, David Mauro, Rose Sheloditna, Alberto Chiappori, Ansuman Bagchi, Gennaro Ciliberto
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-8 (2020)
Abstract Background Human telomerase reverse transcriptase (hTERT) is an antigen that may represent a target for a novel anti-cancer strategy. A pilot, phase I study tested the safety and feasibility of a prime-boost immunization regimen based on V93
Externí odkaz:
https://doaj.org/article/aab4e0ed9d5a4db4b9b409327d52c706
Autor:
Aimin Tang, Zhifeng Chen, Kara S. Cox, Hua-Poo Su, Cheryl Callahan, Arthur Fridman, Lan Zhang, Sangita B. Patel, Pedro J. Cejas, Ryan Swoyer, Sinoeun Touch, Michael P. Citron, Dhanasekaran Govindarajan, Bin Luo, Michael Eddins, John C. Reid, Stephen M. Soisson, Jennifer Galli, Dai Wang, Zhiyun Wen, Gwendolyn J. Heidecker, Danilo R. Casimiro, Daniel J. DiStefano, Kalpit A. Vora
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Respiratory syncytial virus (RSV) is a leading cause of infant hospitalization. Here, the authors isolate a human monoclonal antibody that binds to a highly conserved epitope on the RSV fusion protein, neutralizes RSV A and B subtypes equipotently an
Externí odkaz:
https://doaj.org/article/353ee58e3241465cbd5aae22b7984ad3
Autor:
Jennifer D. Galli, Melanie Horton, Eberhard Durr, Gwendolyn J. Heidecker, Daniel Freed, Arthur Fridman, Dai Wang, Lan Zhang
Publikováno v:
Vaccines, Vol 10, Iss 2, p 184 (2022)
Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to i
Externí odkaz:
https://doaj.org/article/285739d0545a4c29948d2f7d7e701610
Autor:
Dhanasekaran Govindarajan, Liming Guan, Steven Meschino, Arthur Fridman, Ansu Bagchi, Irene Pak, Jan ter Meulen, Danilo R Casimiro, Andrew J Bett
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152209 (2016)
Dengue is one of the most important mosquito-borne infections accounting for severe morbidity and mortality worldwide. Recently, the tetravalent chimeric live attenuated Dengue vaccine Dengvaxia® was approved for use in several dengue endemic countr
Externí odkaz:
https://doaj.org/article/d9159dd00b534679b40888da1c3e0a7b
Autor:
Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman, Eric Minch, Pek Y Lum, Jeffrey R Sachs, Eric E Schadt
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 4, p e69 (2007)
To dissect common human diseases such as obesity and diabetes, a systematic approach is needed to study how genes interact with one another, and with genetic and environmental factors, to determine clinical end points or disease phenotypes. Bayesian
Externí odkaz:
https://doaj.org/article/4e13b757b79a4a65a0ed64bea730fc66
Autor:
Jennifer D. Galli, Melanie Horton, Eberhard Durr, Gwendolyn J. Heidecker, Daniel Freed, Arthur Fridman, Dai Wang, Lan Zhang
Publikováno v:
Vaccines; Volume 10; Issue 2; Pages: 184
Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to i