Výsledky vyhledávání - "Arthur Fisch"

Reformas eleitorais no Brasil contemporâneo: mudanças no sistema proporcional e de financiamento eleitoral

Autor: Arthur Fisch, Lara Mesquita

Publikováno v: Estudos Avançados, Volume: 36, Issue: 106, Pages: 33-53, Published: 28 OCT 2022
Estudos Avançados v.36 n.106 2022
Estudos Avançados
Universidade de São Paulo (USP)
instacron:UFRJ

RESUMO É comum no Brasil observar discussões sobre reformas eleitorais. Tal debate é natural em qualquer democracia e faz parte do processo de evolução do sistema político. Desde 1988, o sistema eleitoral brasileiro já se alterou de forma rele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59df36bd7f787a80247ec53b8630fb06
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-40142022000300033&lng=en&tlng=en

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Akademický článek

The yeast guanine nucleotide exchange factor Sec7 is a bottleneck in spatial protein quality control and detoxifies neurological disease proteins

Autor: Roja Babazadeh, Kara L. Schneider, Arthur Fischbach, Xinxin Hao, Beidong Liu, Thomas Nystrom

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

Abstract ER-to-Golgi trafficking partakes in the sorting of misfolded cytoplasmic proteins to reduce their cytological toxicity. We show here that yeast Sec7, a protein involved in proliferation of the Golgi, is part of this pathway and participates

Externí odkaz: https://doaj.org/article/60431f10ae754d6698580f003827b2ca

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Akademický článek

Calcineurin stimulation by Cnb1p overproduction mitigates protein aggregation and α-synuclein toxicity in a yeast model of synucleinopathy

Autor: Srishti Chawla, Doryaneh Ahmadpour, Kara L. Schneider, Navinder Kumar, Arthur Fischbach, Mikael Molin, Thomas Nystrom

Publikováno v: Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-13 (2023)

Abstract The calcium-responsive phosphatase, calcineurin, senses changes in Ca2+ concentrations in a calmodulin-dependent manner. Here we report that under non-stress conditions, inactivation of calcineurin signaling or deleting the calcineurin-depen

Externí odkaz: https://doaj.org/article/ab5d5a8ba2d04d89bae73f27ec5733e1

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Akademický článek

Artificial Hsp104-mediated systems for re-localizing protein aggregates

Autor: Arthur Fischbach, Angela Johns, Kara L. Schneider, Xinxin Hao, Peter Tessarz, Thomas Nyström

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

Abstract Spatial Protein Quality Control (sPQC) sequesters misfolded proteins into specific, organelle-associated inclusions within the cell to control their toxicity. To approach the role of sPQC in cellular fitness, neurodegenerative diseases and a

Externí odkaz: https://doaj.org/article/0ada2cd12d844cfe88e401e7263d62be

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