Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Arthur F. Wagner"'
Autor:
Arthur F. Wagner, Karl Folkers
Publikováno v:
Advances in Enzymology and Related Areas of Molecular Biology, Volume 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ef70f0561423db678aa3c208911a0b2
https://doi.org/10.1002/9780470122686.ch9
https://doi.org/10.1002/9780470122686.ch9
Autor:
Edward M. Scolnick, A. K. Field, R. L. Tolman, John D. Karkas, Arthur F. Wagner, Clyde S. Crumpacker, John I. Germershausen
Publikováno v:
Biochemical and Biophysical Research Communications. 128:1329-1335
As part of our study of antiherpetic acyclonucleosides, we synthesized a cyclic GMP analog, 9-[(2-hydroxy-1,3,2-dioxaphosphorinan-5-yl)oxymethyl]guanine P-oxide, sodium salt (2′-nor-cGMP), and discovered its potent and broad spectrum anti-DNA-viral
Publikováno v:
Journal of Medicinal Chemistry. 25:457-469
6 beta-[(1-Substituted-4-pyridinio)amino]penam-3-carboxylates and 7 beta-[(1-substituted-4-pyridinio)amino]ceph-3-em-4-carboxylates have been found to be interesting new classes of antibacterial beta-lactams, readily available by SN2 Ar coupling of f
Autor:
Mary Ellen Davies, Richard L. Tolman, John I. Germershausen, Malcolm MacCoss, John D. Karkas, Helen C. Perry, Christine L. Cantone, Timothy L. Schofield, Corrille M. De Witt, A. Kirk Field, Arthur F. Wagner
Publikováno v:
Antiviral Research. 6:329-341
9-[(2-Hydroxy-1,3,2-dioxaphosphorinan-5-yl)oxymethyl]guanine P-Oxide (2′-nor-cGMP), the cyclic phosphate of 2′-nor-deoxyguanosine (2′-NDG) was synthesized by phosphorylation of 2′-NDG and evaluated for antiherpetic activity in cell cultures a
Autor:
John D. Karkas, A. K. Field, Arthur F. Wagner, Malcolm MacCoss, Richard L. Tolman, John I. Germershausen, R. Liou, R. Bostedor
Publikováno v:
Antimicrobial Agents and Chemotherapy. 29:1025-1031
The metabolisms of 9-(1,3-dihydroxy-2-propoxymethyl)guanine (2'NDG) and its cyclic phosphate, 9-[(2-hydroxy-1,3,2-dioxophosphorinan-5-yl) oxymethyl]guanine P-oxide (2'-nor-cGMP), were compared in cultures of primary rabbit kidney cells infected with
Autor:
Richard G. Bostedor, Malcolm MacCoss, John I. Germershausen, Arthur F. Wagner, John D. Karkas, Richard L. Tolman, R. Liou
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 911:127-135
The antiviral compound 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine (2'-nor-2'-deoxyguanosine, 2'-NDG) is phosphorylated by the HSV-1-induced thymidine kinase to the monophosphate (2'-NDG-MP) and this is further phosphorylated by cellular kinases to th
Publikováno v:
Journal of the American Chemical Society. 81:5441-5444
Autor:
Louis H. Peterson, Edward Walton, Frederick W. Holly, Karl Folkers, Frank W. Bachelor, Arthur F. Wagner
Publikováno v:
Journal of the American Chemical Society. 77:5144-5149
Autor:
Arthur F. Wagner
Publikováno v:
Journal of the American Chemical Society. 79:3240-3245
Autor:
John Otto Rodin, Andrew N. Wilson, Karl Folkers, Arthur F. Wagner, Frederick W. Holly, Edward Walton, Norman G. Brink
Publikováno v:
Journal of the American Chemical Society. 81:4983-4989