Photocrosslinking Approach to Investigate Protein Interactions in the BCL-2 Family

Autor: Arthur E. Johnson, Jialing Lin, Zhi Zhang

Publikováno v: Methods in Molecular Biology ISBN: 9781493988600

The Bcl-2 family of proteins regulates mitochondrial outer membrane permeability thereby making life or death decisions for cells. Most of Bcl-2 proteins contain hydrophobic regions that are embedded in intracellular membranes such as mitochondria. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f93db5e0406ea5be5171aec341dca39
https://doi.org/10.1007/978-1-4939-8861-7_9

Disulfide-bond scanning reveals assembly state and β-strand tilt angle of the PFO β-barrel

Autor: Rodney K. Tweten, Takehiro K. Sato, Arthur E. Johnson

Publikováno v: Nature chemical biology

Perfringolysin O (PFO), a bacterial cholesterol-dependent cytolysin, binds to a mammalian cell membrane, oligomerizes into a circular prepore complex (PPC), and forms a 250-Å transmembrane β-barrel pore in the cell membrane. Each PFO monomer has tw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c162394cfcdbbccdb0db517222785638
https://doi.org/10.1038/nchembio.1228

Human peroxin PEX3 is co-translationally integrated into the ER and exits the ER in budding vesicles

Autor: Ismael Mingarro, Peter U. Mayerhofer, Arthur E. Johnson, Manuel Bañó-Polo

Publikováno v: Mayerhofer, Peter U. Bañó Polo, Manuel Mingarro Muñoz, Ismael Johnson, Arthur E. 2016 Human peroxin PEX3 is co-translationally integrated into the ER and exits the ER in budding vesicles Traffic 17 2 117 130
RODERIC. Repositorio Institucional de la Universitat de Valéncia
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Traffic (Copenhagen, Denmark)

The long-standing paradigm that all peroxisomal proteins are imported post-translationally into pre-existing peroxisomes has been challenged by the detection of peroxisomal membrane proteins (PMPs) inside the endoplasmic reticulum (ER). In mammals, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12f474e6663e4925202011ce5a66370
https://doi.org/10.1111/tra.12350

Ligand-Driven Vectorial Folding of Ribosome-Bound Human CFTR NBD1

Autor: Arthur E. Johnson, Amardeep Khushoo, William R. Skach, Zhongying Yang

Publikováno v: Molecular Cell. 41:682-692

Summary The mechanism by which protein folding is coupled to biosynthesis is a critical, but poorly understood, aspect of protein conformational diseases. Here we use fluorescence resonance energy transfer (FRET) to characterize tertiary structural t

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https://doi.org/10.1016/j.molcel.2011.02.027

Membrane Insertion and Biogenesis of the Turnip Crinkle Virus p9 Movement Protein

Autor: Ismael Mingarro, Luis Martínez-Gil, Arthur E. Johnson

Publikováno v: Martínez Gil, Luis Johnson, Arthur E. Mingarro Muñoz, Ismael 2010 Membrane insertion and biogenesis of the Turnip Crinkle Virus p9 movement protein Journal of Virology 84 11 5520 5527
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname

Plant viral infection and spread depends on the successful introduction of a virus into a cell of a compatible host, followed by replication and cell-to-cell transport. The movement proteins (MPs) p8 and p9 of Turnip crinkle virus are required for ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8a35d33703dd0a651faf2d008fbf0b
https://doi.org/10.1128/jvi.00125-10