Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Arthur E Warrington"'
Autor:
Meghan M Painter, James H Morrison, Laurie J Zoecklein, Tommy A Rinkoski, Jens O Watzlawik, Louisa M Papke, Arthur E Warrington, Allan J Bieber, William E Matchett, Kari L Turkowski, Eric M Poeschla, Moses Rodriguez
Publikováno v:
PLoS Pathogens, Vol 11, Iss 12, p e1005311 (2015)
For many emerging and re-emerging infectious diseases, definitive solutions via sterilizing adaptive immunity may require years or decades to develop, if they are even possible. The innate immune system offers alternative mechanisms that do not requi
Externí odkaz:
https://doaj.org/article/a7744516c8e147598d583085c9739909
Publikováno v:
Neurobiology of Disease, Vol 15, Iss 1, Pp 120-131 (2004)
Stabilizing the survival of oligodendrocytes and oligodendrocyte precursors within and near lesions in patients suffering from multiple sclerosis (MS) and other demyelinating diseases is an important therapeutic goal. Previous studies have identified
Externí odkaz:
https://doaj.org/article/b06753077d704b509baf42a6cf70a0a9
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55149 (2013)
Promotion of remyelination is a major goal in treating demyelinating diseases such as multiple sclerosis (MS). The recombinant human monoclonal IgM, rHIgM22, targets myelin and oligodendrocytes (OLs) and promotes remyelination in animal models of MS.
Externí odkaz:
https://doaj.org/article/19d7bfe92e694e078323a2b43e79be07
Autor:
Cecile Riviere-Cazaux, Karishma Rajani, Masum Rahman, Juhee Oh, Desmond A. Brown, Jaclyn F. White, Benjamin T. Himes, Ignacio Jusue-Torres, Moses Rodriguez, Arthur E. Warrington, Sani H. Kizilbash, William F. Elmquist, Terry C. Burns
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background Microdialysis is a technique that can be utilized to sample the interstitial fluid of the central nervous system (CNS), including in primary malignant brain tumors known as gliomas. Gliomas are mainly accessible at the time of sur
Externí odkaz:
https://doaj.org/article/b01726b9a3c24b95811a6ea5c664f995
Autor:
Cecile Riviere-Cazaux, Lucas P. Carlstrom, Bryan J. Neth, Ian E. Olson, Karishma Rajani, Masum Rahman, Samar Ikram, Moustafa A. Mansour, Bipasha Mukherjee, Arthur E. Warrington, Susan C. Short, Thomas von Zglinicki, Desmond A. Brown, Sandeep Burma, Tamar Tchkonia, Marissa J. Schafer, Darren J. Baker, Sani H. Kizilbash, James L. Kirkland, Terry C. Burns
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-12 (2023)
Abstract High-grade gliomas are primary brain tumors that are incredibly refractory long-term to surgery and chemoradiation, with no proven durable salvage therapies for patients that have failed conventional treatments. Post-treatment, the latent gl
Externí odkaz:
https://doaj.org/article/c015455051d141358c38ab0af93970d0
Autor:
Branislav Nastasijevic, Brent R Wright, John Smestad, Arthur E Warrington, Moses Rodriguez, L James Maher
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39595 (2012)
Multiple sclerosis (MS) is a debilitating inflammatory disease of the central nervous system (CNS) characterized by local destruction of the insulating myelin surrounding neuronal axons. With more than 200 million MS patients worldwide, the absence o
Externí odkaz:
https://doaj.org/article/3223afc358d246ce8fcb523a06b8eeca
Autor:
Aleksandar Denic, Slobodan I Macura, Arthur E Warrington, Istvan Pirko, Brandon R Grossardt, Larry R Pease, Moses Rodriguez
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26001 (2011)
Our laboratory demonstrated that a natural human serum antibody, sHIgM12, binds to neurons in vitro and promotes neurite outgrowth. We generated a recombinant form, rHIgM12, with identical properties. Intracerebral infection with Theiler's Murine Enc
Externí odkaz:
https://doaj.org/article/44ecd65ce2a7428083f505efb28aa427
Autor:
Yooree Ha, Karishma Rajani, Cecile Riviere-Cazaux, Masum Rahman, Ian E. Olson, Ali Gharibi Loron, Mark A. Schroeder, Moses Rodriguez, Arthur E. Warrington, Terry C. Burns
Publikováno v:
Cancers, Vol 16, Iss 15, p 2705 (2024)
Aberrant metabolism is a hallmark of malignancies including gliomas. Intracranial microdialysis enables the longitudinal collection of extracellular metabolites within CNS tissues including gliomas and can be leveraged to evaluate changes in the CNS
Externí odkaz:
https://doaj.org/article/a66ab4aa0cfe438c944de4649364f786
Blood-brain barrier disruption defines the extracellular metabolome of live human high-grade gliomas
Autor:
Cecile Riviere-Cazaux, Lucas P. Carlstrom, Karishma Rajani, Amanda Munoz-Casabella, Masum Rahman, Ali Gharibi-Loron, Desmond A. Brown, Kai J. Miller, Jaclyn J. White, Benjamin T. Himes, Ignacio Jusue-Torres, Samar Ikram, Seth C. Ransom, Renee Hirte, Ju-Hee Oh, William F. Elmquist, Jann N. Sarkaria, Rachael A. Vaubel, Moses Rodriguez, Arthur E. Warrington, Sani H. Kizilbash, Terry C. Burns
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract The extracellular microenvironment modulates glioma behaviour. It remains unknown if blood-brain barrier disruption merely reflects or functionally supports glioma aggressiveness. We utilised intra-operative microdialysis to sample the extra
Externí odkaz:
https://doaj.org/article/df7819129fee4a19804cd898e7b157b6
Publikováno v:
Cancers, Vol 15, Iss 4, p 1279 (2023)
High-grade gliomas are the most common and aggressive adult primary brain tumors with a median survival of only 12–15 months. Current standard therapy consists of maximal safe surgical resection followed by DNA-damaging agents, such as irradiation
Externí odkaz:
https://doaj.org/article/b8093d830e0f42a185426fa592ce6901