Zobrazeno 1 - 10
of 319
pro vyhledávání: '"Arthur E, Frankel"'
Autor:
Arthur E. Frankel, Renuka Reddy, Kayla R. DeSuza, Khaled Deeb, Aaron F. Carlin, Davey Smith, Yushuang Xie, Eknath Naik, Richard T. Silver, Hans C. Hasselbalch
Publikováno v:
Clinical Case Reports, Vol 9, Iss 4, Pp 2228-2235 (2021)
Abstract An 83‐year‐old female had asymptomatic SARS‐CoV‐2 infection while taking ruxolitinib. She remained RT‐PCR positive for viral RNA for >120 days, and Pegylated interferon for 4 weeks led to viral RNA clearance. The observations suppo
Externí odkaz:
https://doaj.org/article/1b3e4bbc4f1d4394b1fe594cfe958103
Publikováno v:
Clinical Case Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract A 61‐year‐old male on everolimus had chronic SARS‐CoV‐2 infection. Addition of pegylated interferon cleared viral RNA and supports combination therapy with everolimus plus interferon for COVID‐19.
Externí odkaz:
https://doaj.org/article/ed6db42613e04eafa6b69bb937365a89
Autor:
Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice Wang, Jayastu Senapati, Nathaniel R. Wilson, Marina Konopleva, Arthur E. Frankel, Vikas Gupta, Ruben Mesa, Matthew Ulrickson, Edward Gorak, Sumeet Bhatia, Tulin Budak-Alpdogan, James Mason, Maria Teresa Garcia-Romero, Norma Lopez-Santiago, Gabriela Cesarman-Maus, Pankit Vachhani, Sangmin Lee, Vijaya Raj Bhatt, William Blum, Roland B. Walter, Dale Bixby, Ivana Gojo, Madeleine Duvic, Raajit K. Rampal, Marcos de Lima, James Foran, Amir T. Fathi, Aric Cameron Hall, Meagan A. Jacoby, Jeffrey Lancet, Gabriel Mannis, Anthony S. Stein, Alice Mims, David Rizzieri, Rebecca Olin, Alexander Perl, Gary Schiller, Paul Shami, Richard M. Stone, Stephen Strickland, Matthew J. Wieduwilt, Naval Daver, Farhad Ravandi, Sumithira Vasu, Monica Guzman, Gail J. Roboz, Joseph Khoury, Muzaffar Qazilbash, Phyu P. Aung, Branko Cuglievan, Yazan Madanat, Mohamed A. Kharfan-Dabaja, Anna Pawlowska, Justin Taylor, Martin Tallman, Prajwal Dhakal, Andrew A. Lane
Publikováno v:
Blood. 141:567-578
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with historically poor outcomes and no worldwide consensus treatment approach. Unique among most hematologic malignancies for its frequent cutaneous involvement, BP
Autor:
Arthur E. Frankel, Laura A. Coughlin, Jiwoong Kim, Thomas W. Froehlich, Yang Xie, Eugene P. Frenkel, Andrew Y. Koh
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 10, Pp 848-855 (2017)
This is the first prospective study of the effects of human gut microbiota and metabolites on immune checkpoint inhibitor (ICT) response in metastatic melanoma patients. Whereas many melanoma patients exhibit profound response to ICT, there are fewer
Externí odkaz:
https://doaj.org/article/ea0024564b1a4bd1a29081adc26b618c
Autor:
Arthur E. Frankel, Ugur Eskiocak, Jennifer G. Gill, Stacy Yuan, Vijayashree Ramesh, Thomas W. Froehlich, Chul Ahn, Sean J. Morrison
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 4, Pp 255-260 (2017)
This is the first prospective study of a combination therapy involving a cardenolide and a MEK inhibitor for metastatic melanoma. Whereas BRAF mutant melanomas can exhibit profound responses to treatment with BRAF and MEK inhibitors, there are fewer
Externí odkaz:
https://doaj.org/article/c6ef23590d4242b2a6c0d804b3482a41
Autor:
Arthur E. Frankel MD, Sachin Deshmukh PhD, Amit Reddy MD, John Lightcap PhD, Maureen Hayes, Steven McClellan, Seema Singh PhD, Brooks Rabideau PhD, T. Grant Glover PhD, Bruce Roberts PhD, Andrew Y. Koh MD
Publikováno v:
Integrative Cancer Therapies, Vol 18 (2019)
The past decade has seen tremendous advances in both our understanding of cancer immunosuppressive microenvironments and colonic bacteria facilitated by immune checkpoint inhibitor antibodies and next generation sequencing, respectively. Because an i
Externí odkaz:
https://doaj.org/article/aad2bd1ca75c42c481cbc7b4e261abbb
Autor:
Arthur E. Frankel, Nicholas S. Duesbery, Samuel H. Davis, Arlynn F. Mulne, Terry C. Lairmore, Cynthia J. Meininger, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Solid tumor growth is dependent on angiogenesis, the formation of neovasculature from existing vessels. Endothelial activation of the extracellular signal–regulated kinase 1/2, c-jun NH2-terminal kinase, and p38 mitogen-activated protein kinase pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03886c14138c70a9b7f91f12afb7edb8
https://doi.org/10.1158/1541-7786.c.6542080
https://doi.org/10.1158/1541-7786.c.6542080
Autor:
Arthur E. Frankel, Nicholas S. Duesbery, Samuel H. Davis, Arlynn F. Mulne, Terry C. Lairmore, Cynthia J. Meininger, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Supplementary Data from Matrix Metalloproteinase–Activated Anthrax Lethal Toxin Inhibits Endothelial Invasion and Neovasculature Formation during In vitro Morphogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36db606e85f5ec378b3043d47300b02b
https://doi.org/10.1158/1541-7786.22518703.v1
https://doi.org/10.1158/1541-7786.22518703.v1
Autor:
Arthur E. Frankel, Nicholas S. Duesbery, Samuel H. Davis, Arlynn F. Mulne, Terry C. Lairmore, Cynthia J. Meininger, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Supplementary Figures S1-S3 from Matrix Metalloproteinase–Activated Anthrax Lethal Toxin Inhibits Endothelial Invasion and Neovasculature Formation during In vitro Morphogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05495904eb369ab159c26e652d76956f
https://doi.org/10.1158/1541-7786.22518700
https://doi.org/10.1158/1541-7786.22518700
Autor:
Arthur E. Frankel, Nicholas S. Duesbery, Jennifer L. Bromberg-White, Keiran S. Smalley, Meenhard Herlyn, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Anthrax lethal toxin (LeTx) shows potent mitogen-activated protein kinase pathway inhibition and apoptosis in melanoma cells that harbor the activating V600E B-RAF mutation. LeTx is composed of two proteins, protective antigen and lethal factor. Upta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf49ee34c5b925ff95f8e167b17aaa7
https://doi.org/10.1158/1535-7163.c.6531849
https://doi.org/10.1158/1535-7163.c.6531849