Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Arthur D, Tinoco"'
Autor:
Ámbar M. Alsina-Sánchez, Sebastián Montalvo-Vázquez, Nilmary Grafals-Ruiz, Carmen Acosta, Emily M. Ormé, Israel Rodríguez, Sara M. Delgado-Rivera, Arthur D. Tinoco, Suranganie Dharmawardhane, Ingrid C. Montes-González
Publikováno v:
ACS Omega, Vol 8, Iss 38, Pp 34377-34387 (2023)
Externí odkaz:
https://doaj.org/article/f0555909e260411e907a3d345c1e20ab
Autor:
Oscar Claudio-Ares, Jeileen Luciano-Rodríguez, Yolmarie L. Del Valle-González, Selene L. Schiavone-Chamorro, Alex J. Pastor, Javier O. Rivera-Reyes, Carmen L. Metzler, Lizandra M. Domínguez-Orona, Brenda Lee Vargas-Pérez, Rachid Skouta, Arthur D. Tinoco
Publikováno v:
Inorganics, Vol 12, Iss 1, p 26 (2024)
The discovery of regulated cell death (RCD) revolutionized chemotherapy. With caspase-dependent apoptosis initially being thought to be the only form of RCD, many drug development strategies aimed to synthesize compounds that turn on this kind of cel
Externí odkaz:
https://doaj.org/article/3b880c2711de4e2db4716f90a1644433
Autor:
Kavita Gaur, Sofia C. Pérez Otero, Josué A. Benjamín-Rivera, Israel Rodríguez, Sergio A. Loza-Rosas, Alexandra M. Vázquez Salgado, Eman A. Akam, Liz Hernández-Matias, Rohit K. Sharma, Nahiara Alicea, Martin Kowaleff, Anthony V. Washington, Andrei V. Astashkin, Elisa Tomat, Arthur D. Tinoco
Publikováno v:
JACS Au, Vol 1, Iss 6, Pp 865-878 (2021)
Externí odkaz:
https://doaj.org/article/d093912399c24debb3311d3e81566cd9
Autor:
Aixa M. Orta-Rivera, Yazmary Meléndez-Contés, Nataniel Medina-Berríos, Adriana M. Gómez-Cardona, Andrés Ramos-Rodríguez, Claudia Cruz-Santiago, Christian González-Dumeng, Janangelis López, Jansteven Escribano, Jared J. Rivera-Otero, Josean Díaz-Rivera, Sebastián C. Díaz-Vélez, Zulemaría Feliciano-Delgado, Arthur D. Tinoco
Publikováno v:
Inorganics, Vol 11, Iss 6, p 252 (2023)
Classical antibacterial drugs were designed to target specific bacterial properties distinct from host human cells to maximize potency and selectivity. These designs were quite effective as they could be easily derivatized to bear next-generation dru
Externí odkaz:
https://doaj.org/article/5240717328c24283971183955bdedc72
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Externí odkaz:
https://doaj.org/article/31f7b65f4f1b451784194ad8ae582332
Autor:
Israel Rodríguez, Lauren Fernández-Vega, Andrea N. Maser-Figueroa, Branlee Sang, Patricia González-Pagán, Arthur D. Tinoco
Publikováno v:
Antibiotics, Vol 11, Iss 2, p 158 (2022)
Due to the rapid mutation of pathogenic microorganisms, drug-resistant superbugs have evolved. Antimicrobial-resistant germs may share their resistance genes with other germs, making them untreatable. The search for more combative antibiotic compound
Externí odkaz:
https://doaj.org/article/f5fddf23db764ce6b5928cd22859f86a
Autor:
Louis J. Delinois, Omar De León-Vélez, Adriana Vázquez-Medina, Alondra Vélez-Cabrera, Amanda Marrero-Sánchez, Christopher Nieves-Escobar, Daniela Alfonso-Cano, Delvin Caraballo-Rodríguez, Jael Rodriguez-Ortiz, Jemily Acosta-Mercado, Josué A. Benjamín-Rivera, Kiara González-González, Kysha Fernández-Adorno, Lisby Santiago-Pagán, Rafael Delgado-Vergara, Xaiomy Torres-Ávila, Andrea Maser-Figueroa, Gladimarys Grajales-Avilés, Glorimar I. Miranda Méndez, Javier Santiago-Pagán, Miguel Nieves-Santiago, Vanessa Álvarez-Carrillo, Kai Griebenow, Arthur D. Tinoco
Publikováno v:
Inorganics, Vol 9, Iss 11, p 83 (2021)
The heme protein cytochrome c (Cyt c) plays pivotal roles in cellular life and death processes. In the respiratory chain of mitochondria, it serves as an electron transfer protein, contributing to the proliferation of healthy cells. In the cell cytop
Externí odkaz:
https://doaj.org/article/dfe1538b7c8849238d3ba678d4a463d2
Autor:
Aixa M. Orta-Rivera, Yazmary Meléndez-Contés, Nataniel Rivera-Berríos, Adriana M. Gómez-Cardona, Andrés Ramos-Rodríguez, Claudia Cruz-Santiago, Christian González-Dumeng, Janangelis López, Jansteven Escribano, Jared J. Rivera-Otero, Josean Díaz-Rivera, Sebastián C. Díaz-Vélez, Zulemaría Feliciano-Delgado, Arthur D. Tinoco
Classical antibacterial drugs were designed to target specific bacterial properties distinct from host human cells to maximize potency and selectivity. These designs were quite effective as they could be easily derivatized to bear next generation dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c42cd10865b430e39a93da57b4476eee
https://doi.org/10.20944/preprints202304.1124.v1
https://doi.org/10.20944/preprints202304.1124.v1
Publikováno v:
Biomimetics, Vol 6, Iss 1, p 1 (2020)
Drug development is a decades-long, multibillion dollar investment that often limits itself. To decrease the time to drug approval, efforts are focused on drug targets and drug formulation for optimal biocompatibility and efficacy. X-ray structural c
Externí odkaz:
https://doaj.org/article/c0e30011eea247e3a3bd84b9ab488e79
Autor:
Josué A. Benjamín-Rivera, Andrés E. Cardona-Rivera, Ángel L. Vázquez-Maldonado, Christian Y. Dones-Lassalle, Héctor L. Pabón-Colon, Héctor M. Rodríguez-Rivera, Israel Rodríguez, Jean C. González-Espiet, Jessika Pazol, Jobaniel D. Pérez-Ríos, José F. Catala-Torres, Marielie Carrasquillo Rivera, Michael G. De Jesus-Soto, Nicolle A. Cordero-Virella, Paola M. Cruz-Maldonado, Patricia González-Pagan, Raul Hernández-Ríos, Kavita Gaur, Sergio A. Loza-Rosas, Arthur D. Tinoco
Publikováno v:
Inorganics, Vol 8, Iss 9, p 48 (2020)
Serum transferrin (sTf) plays a pivotal role in regulating iron biodistribution and homeostasis within the body. The molecular details of sTf Fe(III) binding blood transport, and cellular delivery through transferrin receptor-mediated endocytosis are
Externí odkaz:
https://doaj.org/article/727446dfc8a04a3894615c51e4a8126c