Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Arthur Catapang"'
Autor:
Shili Xu, Arthur Catapang, Daniel Braas, Linsey Stiles, Hanna M. Doh, Jason T. Lee, Thomas G. Graeber, Robert Damoiseaux, Orian Shirihai, Harvey R. Herschman
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-17 (2018)
Abstract Background Precision medicine therapies require identification of unique molecular cancer characteristics. Hexokinase (HK) activity has been proposed as a therapeutic target; however, different hexokinase isoforms have not been well characte
Externí odkaz:
https://doaj.org/article/440363d204aa4ccf82544f27f7fe42b8
Autor:
Thomas G. Graeber, Arthur Catapang, Shili Xu, Jason T. Lee, Harvey R. Herschman, Nicholas Bayley, Daniel Braas, Hanna M. Doh
Publikováno v:
J Nucl Med
Although absent in most adult tissues, hexokinase 2 (HK2) is expressed in most tumors and contributes to increased glucose consumption and to in vivo tumor (18)F-FDG PET signaling. Methods: Both HK2 knockdown and knockout approaches were used to inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3188374e39585644ecba4b64dff2895a
https://doi.org/10.2967/jnumed.118.212365
https://doi.org/10.2967/jnumed.118.212365
Autor:
Erin M. Foley, Harvey R. Herschman, Arthur Catapang, Roger Lawrence, Jeffrey D. Esko, Ramon Alemany, Hamidreza Hoveida, Patrick Secrest, Anne K. Zaiss, Dmitry M. Shayakhmetov, Yu Yamaguchi, Lina S. Schneider
Publikováno v:
Journal of virology, vol 90, iss 1
Adeno-associated virus 2 (AAV2) and adenovirus 5 (Ad5) are promising gene therapy vectors. Both display liver tropism and are currently thought to enter hepatocytes in vivo through cell surface heparan sulfate proteoglycans (HSPGs). To test directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c59c7e5e5863fb067797e494f275cb
https://europepmc.org/articles/PMC4702579/
https://europepmc.org/articles/PMC4702579/
Autor:
Harvey R. Herschman, Jason T. Lee, Robert Damoiseaux, Arthur Catapang, Thomas G. Graeber, Shili Xu, Daniel Braas, Orian S. Shirihai, Linsey Stiles
Publikováno v:
Molecular Cancer Therapeutics. 16:B37-B37
Despite increasing prevalence and lethality for hepatocellular carcinoma (HCC), the need for effective treatment remains unmet. Metabolic reprogramming during hepatocarcinogenesis promotes cancer cell growth and survival, but also suggests the possib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b772cf9d4387e69102d2ab4408cb43d
https://doi.org/10.1158/1538-8514.synthleth-b37
https://doi.org/10.1158/1538-8514.synthleth-b37
Autor:
Arthur Catapang, Tomo-o Ishikawa, Chun Chu, Hidevaldo B. Machado, Jose S. Gil, Anne K. Zaiss, Scott W. Lowe, Harvey R. Herschman, Johannes Zuber, Jing Jiao
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 7, p e101263 (2014)
PLoS ONE, Vol 9, Iss 7, p e101263 (2014)
Prostaglandin-endoperoxide synthase 2 (PTGS2), also known as cyclooxygenase 2 (COX-2), plays a critical role in many normal physiological functions and modulates a variety of pathological conditions. The ability to turn endogenous COX-2 on and off in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad48c423cfead691320cdc9717170604
http://europepmc.org/articles/PMC4079684
http://europepmc.org/articles/PMC4079684