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Stempel, Da, Raphiou, Ih, Kral, Km, Yeakey, Am, Emmett, Ah, Prazma, Cm, Buaron, Ks, Pascoe, Sj, Austri, Investigators, Altieri, Hh, Antuni, Jd, Bergna, Ma, Cuadrado, Ja, De Gennaro MS, Fazio Lizandrelo CL, Gattolin, G, Gosn, Am, Larrateguy, Ld, Marcipar, Am, Maspero, Jf, Medina, Iv, Perez Chada RD, Silva, D, Victorio, Cf, Bardin, Pg, Carroll, Pa, Clements, Bs, Dore, Nd, Robinson, Pd, Fitzgerald, Da, Robinson, Pj, Russo, Ma, Sajkov, D, Thomas, Ps, Upham, Jw, Forstner, B, Kaik, G, Koeberl, Gh, Studnicka, M, Wallner, G, Balthazar, Y, Bauler, A, Dupont, Lj, Martinot, Jb, Ninane, V, Peché, R, Pilette, C, Dimitrova, R, Dimova, D, Kissyova Ibrishimova, G, Loboshka Becheva, M, Machkovska, M, Madjarov, S, Mandazhieva Pepelanova, M, Naidenova, I, Noleva, K, Takovska, N, Terziev, C, Aggarwal, Nk, Chapman, Kr, Csanadi, Ma, Dhillon, R, Henein, S, Kelly, Aj, Lam, As, Liem, Jj, Lougheed, Md, Lowe, Dw, Rizvi, Q, van den Berg, L, Zidel, B, Barros Monge MJ, Calvo Gil MA, Castillo Hofer CR, Diaz Amor PV, Lezana Soya, V, Quilodran Silva CN, Bolivar Grimaldos, F, Solarte-Rodriguez, I, Butkovic-Tomljanovic, R, Hegedus-Jungvirth, M, Ivkovic-Jurekovic, I, Simunov-Karuza, G, Buresova, M, Bursova, J, Fratrik, J, Guttlerova, E, Hartman, P, Jirmanova, I, Kalina, P, Kolman, P, Kucera, M, Povysilova, L, Pravda, P, Svabkova, A, Zakova, L, Backer, V, Maltbaek, N, Johnsen, Cr, Aries, Sp, Babyesiza, A, Barth, D, Benedix, A, Berg, P, Bergtholdt, B, Bettig, U, Bindig, Hw, Botzen, U, Brehler, R, Breyer, Go, Bruckhaus-Walter, M, Dapper, T, Eckhard, Jg, Engelhard, R, Feldmeyer, F, Fissan, H, Franz, Kh, Frick, Bs, Funck, J, Gessner, Cm, Ginko, T, Grigat, Ce, Grimm-Sachs, V, Groth, G, Hampf, J, Hanf, G, Havasi-Jost, G, Heinz, Gu, Helm, K, Hoeltz, S, Hofmann, S, Jander, R, Jandl, M, Jasch-Hoppe, B, Jung, T, Junggeburth, Jj, Kardos, P, Knueppel, W, Koch, T, Kolorz, C, Korduan, M, Korth-Wiemann, B, Krezdorn, Hg, Kroker, A, Kruell, M, Kuehne, P, Lenk, U, Liefring, E, Merke, J, Micke, L, Mitlehner, W, Mueller, 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Zhiglinskaya, O, Zykov, K, Dopudja Pantic, V, Nadaskic, R, Nestorovic, B, Skodric Trifunovic, V, Stojanovic, A, Vukcevic, M, Vujic, T, Mitic Milikic, M, Banovcin, P, Horvathova, H, Karako, P Sr, Plutinsky, J, Pribulova, E, Szarazova, M, Zlatos, A, Adams, L, Badat, A, Bassa, A, Breedt, J, Bruning, A, Ellis, Gc, Emanuel, S, Fouche, Lf, Fulat, Ma, Gani, M, Ismail, Ms, Jurgens, Jc, Nell, H, Nieuwoudt, G, Noor, F, Bolliger, Ct, Puterman, As, Siddique, N, Trokis, Js, Vahed, Ya, Van Der Berg BJ, Van der Linden, M, Van Zyl, L, Visser, Ss, Antépara Ercoreca, I, Arnedillo Muñoz, A, Barbe Illa, F, Barreiro López, B, Blanco Aparicio, M, Boada Valmaseda, A, Bosque García, M, Bustamante Ruiz, A, Carretero Anibarro, P, Del Campo Matias, F, Echave-Sustaet, Jm, Espinosa de los Monteros Garde MJ, Garcia Hernandez GM, López Viña, A, Lores Obradors, L, Luengo Planas MT, Monsó Molas, E, Navarro Dourdil, A, Nieto García AJ, Perpina Tordera, M, Picado Valles, C, Rodriguez Alvarez Mdel, M, Saura Vinuesa, A, 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Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Universitad de Lleida
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
BACKGROUND The safe and appropriate use of long-acting beta-agonists (LABAs) for the treatment of asthma has been widely debated. In two large clinical trials, investigators found a potential risk of serious asthma-related events associated with LABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ebce448b28f9d6c01d4a59e66f2706
http://hdl.handle.net/10459.1/65688
http://hdl.handle.net/10459.1/65688
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Publikováno v:
The Lancet; 1996, Vol. 348 Issue: 9030 p771-775, 5p
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Sun D; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA., Storek KM; Department of Infectious Diseases, Genentech Inc., South San Francisco, CA, USA., Tegunov D; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA., Yang Y; Department of Discovery Chemistry, Genentech Inc., South San Francisco, CA, USA., Arthur CP; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA.; Altos Labs, Redwood City, CA, USA., Johnson M; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA., Quinn JG; Department of Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA, USA., Liu W; Department of Microchemistry, Proteomics and Lipidomics, Genentech Inc., South San Francisco, CA, USA., Han G; Department of Microchemistry, Proteomics and Lipidomics, Genentech Inc., South San Francisco, CA, USA.; PTM Bio, Alameda, CA, USA., Girgis HS; Department of Infectious Diseases, Genentech Inc., South San Francisco, CA, USA., Alexander MK; Department of Infectious Diseases, Genentech Inc., South San Francisco, CA, USA., Murchison AK; Department of Infectious Diseases, Genentech Inc., South San Francisco, CA, USA., Shriver S; Department of BioMolecular Resources, Genentech Inc., South San Francisco, CA, USA., Tam C; Department of BioMolecular Resources, Genentech Inc., South San Francisco, CA, USA., Ijiri H; PeptiDream Inc., Kawasaki, Kanagawa, Japan., Inaba H; PeptiDream Inc., Kawasaki, Kanagawa, Japan., Sano T; PeptiDream Inc., Kawasaki, Kanagawa, Japan., Yanagida H; PeptiDream Inc., Kawasaki, Kanagawa, Japan., Nishikawa J; PeptiDream Inc., Kawasaki, Kanagawa, Japan., Heise CE; Department of Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA, USA.; Septerna, South San Francisco, CA, USA., Fairbrother WJ; Department of Early Discovery Biochemistry, Genentech Inc., South San Francisco, CA, USA., Tan MW; Department of Infectious Diseases, Genentech Inc., South San Francisco, CA, USA., Skelton N; Department of Discovery Chemistry, Genentech Inc., South San Francisco, CA, USA., Sandoval W; Department of Microchemistry, Proteomics and Lipidomics, Genentech Inc., South San Francisco, CA, USA., Sellers BD; Department of Discovery Chemistry, Genentech Inc., South San Francisco, CA, USA.; Vilya, South San Francisco, CA, USA., Ciferri C; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA., Smith PA; Department of Infectious Diseases, Genentech Inc., South San Francisco, CA, USA.; Revagenix, San Mateo, CA, USA., Reid PC; PeptiDream Inc., Kawasaki, Kanagawa, Japan., Cunningham CN; Department of Peptide Therapeutics, Genentech Inc., South San Francisco, CA, USA. C-cunningham@peptidream.com.; PeptiDream, Kawasaki, Japan. C-cunningham@peptidream.com., Rutherford ST; Department of Infectious Diseases, Genentech Inc., South San Francisco, CA, USA. rutherford.steven@gene.com., Payandeh J; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA. jpayandeh@exelixis.com.; Department of Infectious Diseases, Genentech Inc., South San Francisco, CA, USA. jpayandeh@exelixis.com.; Exelixis, Alameda, CA, USA. jpayandeh@exelixis.com.
Publikováno v:
Nature communications [Nat Commun] 2024 Oct 08; Vol. 15 (1), pp. 8718. Date of Electronic Publication: 2024 Oct 08.
Autor:
Kung JE; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA., Johnson MC; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA., Jao CC; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA., Arthur CP; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA., Tegunov D; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA., Rohou A; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA., Sudhamsu J; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 May 13. Date of Electronic Publication: 2024 May 13.
Autor:
Kschonsak M; Genentech Inc, Structural Biology, South San Francisco, United States., Jao CC; Genentech Inc, Structural Biology, South San Francisco, United States., Arthur CP; Genentech Inc, Structural Biology, South San Francisco, United States., Rohou AL; Genentech Inc, Structural Biology, South San Francisco, United States., Bergeron P; Genentech Inc, Discovery Chemistry, South San Francisco, United States., Ortwine DF; Genentech Inc, Discovery Chemistry, South San Francisco, United States., McKerrall SJ; Genentech Inc, Discovery Chemistry, South San Francisco, United States., Hackos DH; Genentech Inc, Neuroscience, South San Francisco, United States., Deng L; Genentech Inc, Neuroscience, South San Francisco, United States., Chen J; Genentech Inc, Biochemical and Cellular Pharmacology, South San Francisco, United States., Li T; Genentech Inc, Biochemical and Cellular Pharmacology, South San Francisco, United States., Dragovich PS; Genentech Inc, Discovery Chemistry, South San Francisco, United States., Volgraf M; Genentech Inc, Discovery Chemistry, South San Francisco, United States., Wright MR; Genentech Inc, Drug Metabolism and Pharmacokinetics, South San Francisco, United States., Payandeh J; Genentech Inc, Structural Biology, South San Francisco, United States., Ciferri C; Genentech Inc, Structural Biology, South San Francisco, United States., Tellis JC; Genentech Inc, Discovery Chemistry, South San Francisco, United States.
Publikováno v:
ELife [Elife] 2023 Mar 28; Vol. 12. Date of Electronic Publication: 2023 Mar 28.
Autor:
Noreng S; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA., Ota N; Department of Immunology, Genentech Inc., South San Francisco, CA, 94080, USA., Sun Y; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA, 94080, USA., Ho H; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA., Johnson M; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA., Arthur CP; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA.; Altos Labs Inc, Redwood City, CA, 94065, USA., Schneider K; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA, 94080, USA., Lehoux I; Department of Biomolecular Resources, Genentech Inc., South San Francisco, CA, 94080, USA.; Frontier Medicines, South San Francisco, CA, 94080, USA., Davies CW; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA, 94080, USA., Mortara K; Department of Biomolecular Resources, Genentech Inc., South San Francisco, CA, 94080, USA.; Expression Systems, LLC, Davies, CA, 95618, USA., Wong K; DevSci OMNI-Biomarker Development, Genentech Inc., South San Francisco, CA, 94080, USA., Seshasayee D; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA, 94080, USA., Masureel M; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA. masureel.matthieu@gene.com., Payandeh J; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA. jpayandeh@exelixis.com.; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA, 94080, USA. jpayandeh@exelixis.com.; Exelixis Inc., Alameda, CA, 94502, USA. jpayandeh@exelixis.com., Yi T; Department of Immunology, Genentech Inc., South San Francisco, CA, 94080, USA. tangshengy@gmail.com.; Gilead Sciences Inc., Foster City, CA, 9440, USA. tangshengy@gmail.com., Koerber JT; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA, 94080, USA. koerber.james@gene.com.
Publikováno v:
Nature communications [Nat Commun] 2022 Oct 14; Vol. 13 (1), pp. 6079. Date of Electronic Publication: 2022 Oct 14.
Autor:
Noland CL; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA.; Department of Computational and Structural Chemistry, Merck Research Labs, South San Francisco, CA, 94080, USA., Chua HC; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, DK 2100, Denmark., Kschonsak M; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA., Heusser SA; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, DK 2100, Denmark., Braun N; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, DK 2100, Denmark.; Department of Drug Discovery Sciences, Boehringer Ingelheim RCV, Vienna, AU, 1121, Austria., Chang T; Department of BioMolecular Resources, Genentech Inc., South San Francisco, CA, 94080, USA., Tam C; Department of BioMolecular Resources, Genentech Inc., South San Francisco, CA, 94080, USA., Tang J; Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc., South San Francisco, CA, 94080, USA., Arthur CP; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA., Ciferri C; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA. ciferri.claudio@gene.com., Pless SA; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, DK 2100, Denmark. stephan.pless@sund.ku.dk., Payandeh J; Department of Structural Biology, Genentech Inc., South San Francisco, CA, 94080, USA. jpayandeh@interlinetx.com.; Department of Proteomics and Bioinformatics, Interline Therapeutics, South San Francisco, CA, 94080, USA. jpayandeh@interlinetx.com.
Publikováno v:
Nature communications [Nat Commun] 2022 Mar 17; Vol. 13 (1), pp. 1416. Date of Electronic Publication: 2022 Mar 17.