MGluR5 mediates the interaction between late-LTP, network activity, and learning.

Autor: Arthur Bikbaev, Sergey Neyman, Richard Teke Ngomba, P Jeffrey Conn, Ferdinando Nicoletti, Denise Manahan-Vaughan

Publikováno v: PLoS ONE, Vol 3, Iss 5, p e2155 (2008)

Hippocampal synaptic plasticity and learning are strongly regulated by metabotropic glutamate receptors (mGluRs) and particularly by mGluR5. Here, we investigated the mechanisms underlying mGluR5-modulation of these phenomena. Prolonged pharmacologic

Externí odkaz: https://doaj.org/article/61cad06c517f4eaa91878c406480bb4c

Hippocampal network activity is transiently altered by induction of long-term potentiation in the dentate gyrus of freely behaving rats

Autor: Arthur Bikbaev, Denise Manahan-Vaughan

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 1 (2007)

A role for oscillatory activity in hippocampal neuronal networks has been proposed in sensory encoding, cognitive functions and synaptic plasticity. In the hippocampus, theta (5–10 Hz) and gamma (30–100 Hz) oscillations may provide a mechanism fo

Externí odkaz: https://doaj.org/article/bf7c40ad8f5f4ea795a52d3f54e5ea13

Separation of presynaptic Cav2 and Cav1 channel function in synaptic vesicle exo- and endocytosis by the membrane anchored Ca2+ pump PMCA

Autor: Stefanie Ryglewski, Martin Heine, Arthur Bikbaev, Aylin Pichler, Ulrich Thomas, Carsten Duch, Torsten W.B. Götz, Niklas Krick, Oliver Kobler

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences, 118(28):e2106621118

Significance Synaptic vesicle (SV) release from presynaptic terminals requires nanometer precise control of action potential (AP)–triggered calcium influx through voltage-gated calcium channels (VGCCs). SV recycling also depends on calcium signals,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a82ff3d2dbee2a27aec11a02807f1f0
http://europepmc.org/articles/PMC8285953

Calcium channel subunit α2σ4 is regulated by early growth response 1 and facilitates epileptogenesis

Autor: Erick Martinez-Chavez, Arthur Bikbaev, Martin Heine, Johannes Alexander Müller, Sandra Blaess, Dirk Dietrich, Julika Pitsch, Christine K. Rummel, Albert J. Becker, Karen M.J. van Loo, Susanne Schoch

Publikováno v: van Loo, K M J, Rummel, C K, Pitsch, J, Müller, J A, Bikbaev, A F, Martinez-Chavez, E, Blaess, S, Dietrich, D, Heine, M, Becker, A J & Schoch, S 2019, ' Calcium channel subunit α2σ4 is regulated by early growth response 1 and facilitates epileptogenesis ', Journal of Neuroscience, vol. 39, no. 17, pp. 3175-3187 . https://doi.org/10.1523/JNEUROSCI.1731-18.2019
Journal of Neuroscience, 39(17), 3175-3187. Society for Neuroscience

Transient brain insults, including status epilepticus (SE), can trigger a period of epileptogenesis during which functional and structural reorganization of neuronal networks occurs resulting in the onset of focal epileptic seizures. In recent years,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71209696fcf771c1ae315c8d16d9e306
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85065336425&origin=inward

Molecular dynamics of neuronal information transfer

Autor: Martin Heine, Arthur Bikbaev

Publikováno v: Neuroforum. 24:A73-A84

A detailed analysis of synapses as connecting elements between neurons is of central importance to understand the brain’s cognitive performance and its constraints. Nowadays, state-of-the-art optical methods make possible to localize individual mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3b2e75c1278795f68b6852a5ddfa6ee
https://doi.org/10.1515/nf-2017-a042