Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Arthur Bank"'
Autor:
Arthur Bank
This book describes the life and times of a physician-scientist over the last half-century. Part One is about the author's struggle with colon cancer and the lessons he learnt from the experience; Part Two is about his life growing up, the pretzel ba
Publikováno v:
Scandinavian Journal of Haematology. 7:465-470
Longevity in patients with well-documented homozygous β thalassaemia is quite uncommon. This report describes a family with two brothers with β thalassaemia of intermediate severity who lived until ages 34 and 51. The older sibling had a haemoglobi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b033fc8a264b368798f8bd365b63ee6b
https://doi.org/10.1111/j.1600-0609.1970.tb01933.x
https://doi.org/10.1111/j.1600-0609.1970.tb01933.x
Autor:
Arthur Bank
Publikováno v:
Pediatric Hematology and Oncology. 25:1-4
Human globin gene therapy is a potential cure for sickle cell disease and beta-thalassemia (Cooley anemia). A clinical trial of this treatment is currently under way in Paris using lentiglobin vectors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd7352018c46fe332fb89f7088d1783
https://doi.org/10.1080/08880010701773829
https://doi.org/10.1080/08880010701773829
Autor:
Arthur Bank
Publikováno v:
Journal of Clinical Investigation. 117:1746-1749
Normal human hemoglobin (Hb) formation and function is one of the marvels of human evolution and the process of natural selection. Get it right and you have the best functional molecule ever known to pick up oxygen in the lungs and deliver it to need
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3186e8c3ecbb86edf33126c70d8f463e
https://doi.org/10.1172/jci32362
https://doi.org/10.1172/jci32362
Autor:
Arthur Bank
Publikováno v:
Blood. 107:435-443
The human globin genes are among the most extensively characterized in the human genome, yet the details of the molecular events regulating normal human hemoglobin switching and the potential reactivation of fetal hemoglobin in adult hematopoietic ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a4d8fd9b5b081362493a1b6544457e
https://doi.org/10.1182/blood-2005-05-2113
https://doi.org/10.1182/blood-2005-05-2113
Publikováno v:
Annals of the New York Academy of Sciences. 1054:308-316
Recent success in the long-term correction of mouse models of human beta-thalassemia and sickle cell anemia by lentiviral vectors and evidence of high gene transfer and expression in transduced human hematopoietic cells have led to a first clinical t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f9a12beedb8184caf3f984e0400d6c
https://doi.org/10.1196/annals.1345.007
https://doi.org/10.1196/annals.1345.007
Autor:
Engracio P Cortes, James F Holland, Jaw J Wang, Lucius F Sinks, Johannes Blom, Hansjurg Senn, Arthur Bank, Oliver Glidewell, Henry H Sherk
Publikováno v:
Clinical Orthopaedics and Related Research. :5-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d3209fcee6f343ef659b088ddfc3725
https://doi.org/10.1097/01.blo.0000180428.42894.b3
https://doi.org/10.1097/01.blo.0000180428.42894.b3
Autor:
Rocio Lopez, Dianne Pulte, Maureen Ward, Christine Richardson, David O'Neill, Arthur Bank, Shane T. Baker, Ellen K. Ritchie
Publikováno v:
American Journal of Hematology. 81:12-18
Ikaros is a critical transcriptional regulator of hematopoietic cell differentiation. In addition to its effects on the lymphoid system and hematopoietic stem-cell compartment, we have previously shown that Ikaros is also required for normal erythroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905f6ff271f176d5e8eff96276e7e98d
https://doi.org/10.1002/ajh.20507
https://doi.org/10.1002/ajh.20507
Autor:
I.Robert Grossman, M. Brigid Bradley, Rose M Sattler, Arthur Bank, Maureen Ward, Tim M. Townes, Harry Raftopoulos, Thomas M. Ryan
Publikováno v:
Biology of Blood and Marrow Transplantation. 8(8):453-461
Gene therapy, the replacement of normal human beta- or gamma-globin genes into the hematopoietic stem cells of patients with homozygous beta-thalassemia, is a promising therapy for the future. High-level lineage-specific stable globin expression in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3959d32f4b21a1d095abc9f24b2536
Publikováno v:
Proceedings of the National Academy of Sciences. 99:602-607
We have previously reported the structure of a chromatin remodeling complex (PYR complex) with Ikaros as its DNA binding subunit that is specifically present in adult murine and human hematopoietic cells. We now show that homozygous Ikaros “knockou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5551b38d37b55ac747d32154755da232
https://doi.org/10.1073/pnas.022412699
https://doi.org/10.1073/pnas.022412699