Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Arthur B. Parkes"'
Autor:
D. Dall'Amico, Arthur B Parkes, Robert Burns, Elizabeth N. Pearce, Mohammed Jooman, Aldo Maina, Jonathan P. Bestwick, Angela M. Leung, Xuemei He, Peter P.A. Smyth, Lewis E. Braverman, D.F. Smith, John H. Lazarus
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 95:3207-3215
Context: Thyroid hormone, requiring adequate maternal iodine intake, is critical for fetal neurodevelopment. Perchlorate decreases thyroidal iodine uptake by competitively inhibiting the sodium/iodide symporter. It is unclear whether environmental pe
Autor:
Arthur B. Parkes, A. W. Thomas, L. M. Evans, John Lazarus, Onyebuchi E. Okosieme, Lakdassa D. K. E. Premawardhana
Publikováno v:
Thyroid. 16:953-960
In Hashimoto's thyroiditis (HT), there is evidence for activation of peripheral T-lymphocytes that predominantly express a T helper 1 (T(H)1) cytokine bias. However, the immunomodulatory factors involved in regulating this response have so far receiv
Autor:
Pierre-Jean Lejeune, Lakdassa D. K. E. Premawardhana, W. N. Kaluarachi, Peter P.A. Smyth, Onyebuchi E. Okosieme, John Lazarus, Arthur B Parkes, A. Jayasinghe, Jean Ruf
Publikováno v:
Thyroid. 15:1067-1072
Introduction: We previously reported a high thyroglobulin autoantibodies (TgAb) prevalence in healthy Sri Lankans after iodine supplementation. In the present study 58 TgAb-positive schoolgirls were followed up after 5 years of continued iodination.
Publikováno v:
Thyroid. 14:610-615
Thyroid peroxidase antibodies (TPOAb) in pregnancy are a marker for postpartum (PPTD) and long-term thyroid dysfunction, with variable sensitivity and specificity in PPTD prediction. To test its utility in prediction, we recruited 308 TPOAb-positive
Autor:
M. Lage, John H. Lazarus, G. Mazziotti, Felipe F. Casanueva, Lakdasa Premawardhana, Arthur B Parkes
Publikováno v:
Clinical Endocrinology. 60:208-213
Summary background There is experimental evidence that leptin is required for the development of T helper 1 (Th1)-mediated autoimmune diseases. However, to our knowledge, there are no studies demonstrating such a role in human autoimmune thyroid dise
Autor:
A. Jayasinghe, D F Smith, Peter P.A. Smyth, W. N. Kaluarachi, Lakdasa Premawardhana, H. Adams, Chandrika N Wijeyaratne, John Lazarus, G. Mazziotti, Arthur B Parkes, D.G.H. de Silva
Publikováno v:
European Journal of Endocrinology. :103-110
OBJECTIVE: To study the evolution of thyroid autoimmunity, in relation to the change in goitre prevalence, during 3 Years of iodine prophylaxis in Sri Lanka. METHODS: Two groups of Sri Lankan schoolgirls between the ages of 10.8 and 17.5 Years were s
Autor:
Jean Ruf, A. Jayasinghe, Pierre-Jean Lejeune, John H. Lazarus, Arthur B Parkes, D.G.H. de Silva, Onyebuchi E. Okosieme, Peter P.A. Smyth, Lakdassa D. K. E. Premawardhana
Publikováno v:
Clinical Endocrinology. 59:190-197
objective We previously reported a high prevalence of raised thyroglobulin autoantibodies (TgAb) in apparently healthy Sri Lankan schoolgirls following salt iodination. To characterize these antibodies further we determined the epitopes on thyroglobu
Autor:
Arthur B Parkes, Amal A Kokandi, Lakdassa D. K. E. Premawardhana, John Lazarus, Robert A. John
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:1126-1132
Postpartum thyroid dysfunction (PPTD) develops during the first 9 months in up to 50% of women who have thyroid peroxidase antibodies (anti-TPOAb +ve). Humoral immunity in PPTD has been well documented, but the cellular immunological events accompany
Publikováno v:
International Journal of Social Psychiatry. 49:70-76
Background: Postnatal depression is more common in women positive for thyroid autoantibodies, independent of thyroid hormone dysfunction, but the basis of this association is unclear. Aims: The objective of the work reported here has been to investig
Autor:
C. J. Richards, Rossana G. Oretti, Brian Harris, Robert G. Newcombe, Rees John, Arthur B Parkes, John Lazarus, Reginald Hall
Publikováno v:
British Journal of Psychiatry. 180:327-330
BackgroundWomen who are positive for thyroid antibodies in early gestation are prone to post-partum depression, apparently independent of thyroid dysfunction, as measured by serum levels of free thyroxine, free triodothyroxine and thyroid-stimulating