Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Arthur A.P. Meekel"'
Publikováno v:
Pure and Applied Chemistry. 68:2025-2028
Antibodies were generated against a bicyclic transition state analogue of the Diels-Alder reaction between piperylene and an arylnitroso dienophile. One of the antibodies (309-1G7) showed a good rate enhancement of the reaction between cis-piperylene
Publikováno v:
ChemInform. 22
An expedient and enantiospecific synthesis of a strategically functionalized tricyclic intermediate for the construction of manzamine A is described.
Publikováno v:
Tetrahedron. 47:2005-2026
An expedient and enantiospecific synthesis of a strategically functionalized tricyclic intermediate for the construction of manzamine A is described.
Autor:
Marina Resmini, Hans Poppe, M.H.A. Busch, Arthur A.P. Meekel, Hans F. M. Boelens, Johan C. Kraak
Publikováno v:
Journal of Chromatography A, 744, 195-203. Elsevier
The applicability of capillary zone electrophoresis (CZE) for the determination of association constant of an hapten-antibody complex with values as high as 10 7 (mol/1) −1 was investigated (dissociation constant in the nmol range). As a reference
Publikováno v:
Bioorganicmedicinal chemistry. 4(7)
The Diels—Alder cycloadditions of trans- and cis-piperylene (1 and 2) to 4-nitroso-N-propylbenzamide (3) were selected as target reactions for the development of catalytic antibodies with regioselective and enantioselective properties (Meekel, A. A
Publikováno v:
J. Chem. Soc., Chem. Commun.. :571-572
Two transition-state directed antibodies catalyse a Diels–Alder reaction between a 1,3-diene and an arylnitroso dienophile; one of the antibodies shows a good rate enhancement (kcat/kuncat= 1205) and steers the reaction in favour of the targeted is