Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Arthur A. Cross-Najafi"'
Autor:
Arthur A. Cross-Najafi, Kristine Farag, Abdulkadir Isidan, Wei Li, Wenjun Zhang, Zhansong Lin, Julia R. Walsh, Kevin Lopez, Yujin Park, Nancy G. Higgins, David K.C. Cooper, Burcin Ekser, Ping Li
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Natural killer (NK) cells play an important role in immune rejection in solid organ transplantation. To mitigate human NK cell activation in xenotransplantation, introducing inhibitory ligands on xenografts via genetic engineering of pigs may protect
Externí odkaz:
https://doaj.org/article/0f9b4e3e3d83439d9ceb8f80ce35db53
Autor:
Kevin J. Lopez, John Paul Spence, Wei Li, Wenjun Zhang, Barry Wei, Arthur A. Cross-Najafi, James R. Butler, David K. C. Cooper, Burcin Ekser, Ping Li
Publikováno v:
Cells, Vol 12, Iss 22, p 2587 (2023)
Natural killer (NK) cells play a vital role in xenotransplantation rejection. One approach to induce NK cell immune tolerance is to prevent the NK cell-mediated direct killing of porcine cells by targeting the interaction of the activating receptor N
Externí odkaz:
https://doaj.org/article/f194ae4d408145179c6a8b98c224a0d0
Autor:
Kevin J. Lopez, Arthur A. Cross-Najafi, Kristine Farag, Benjamin Obando, Deepthi Thadasina, Abdulkadir Isidan, Yujin Park, Wenjun Zhang, Burcin Ekser, Ping Li
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Eliminating major xenoantigens in pig cells has drastically reduced human antibody-mediated hyperacute xenograft rejection (HXR). Despite these advancements, acute xenograft rejection (AXR) remains one of the major obstacles to clinical xenotransplan
Externí odkaz:
https://doaj.org/article/c3af84d9af5e4799b616044637c49274
Autor:
Arthur A. Cross-Najafi, Kevin Lopez, Abdulkadir Isidan, Yujin Park, Wenjun Zhang, Ping Li, Sezai Yilmaz, Sami Akbulut, Burcin Ekser
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Preclinical trials of pig-to-nonhuman primate liver xenotransplantation have recently achieved longer survival times. However, life-threatening thrombocytopenia and coagulation dysregulation continue to limit preclinical liver xenograft survival time
Externí odkaz:
https://doaj.org/article/d71f690238c34f8c8d25618e2c9d8e3b
Autor:
Wenjun Zhang, Konstantina Kyritsi, Abdulkadir Isidan, Yujin Park, Ping Li, Arthur A Cross-Najafi, Kevin Lopez, Lindsey Kennedy, Keisaku Sato, Shannon Glaser, Heather Francis, Gianfranco Alpini, Burcin Ekser
Organoids are novelin vitromodels to study intercellular crosstalk between the different types of cells in the pathophysiology of disease. To better understand the underlying mechanisms driving the progression of primary sclerosing cholangitis (PSC),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::159c605ba9863d25e6a237c73b0cbcf0
https://doi.org/10.1101/2022.10.24.513594
https://doi.org/10.1101/2022.10.24.513594
Autor:
Yujin Park, Deepthi Thadasina, Ifeoluwa Bolujo, Abdulkadir Isidan, Arthur A. Cross-Najafi, Kevin Lopez, Ping Li, Andrew M. Dahlem, Lindsey Kennedy, Keisaku Sato, Heather Francis, Gianfranco Alpini, Wenjun Zhang, Burcin Ekser
Publikováno v:
Seminars in liver disease. 42(4)
Despite the rising prevalence of nonalcoholic fatty liver disease (NAFLD), the underlying disease pathophysiology remains unclear. There is a great need for an efficient and reliable “human” in vitro model to study NAFLD and the progression to no
Autor:
Kevin Lopez, Arthur A Cross-Najafi, Kadir Isidan, Yujin Park, Jonathan A Fridell, Wenjun Zhang, Ping Li, Burcin Ekser
Publikováno v:
Transplantation. 106:S421-S422
Publikováno v:
The Journal of Cell Biology
Gihana et al. demonstrate that Cdc14 phosphatase activity, released from the nucleolus through the mitotic exit network, terminates the asymmetric localization of Cdc42 at the end of mitosis in budding yeast. Redistribution of Cdc42 activity between
Autor:
Isidan A; Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana., Yenigun A; Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana; Department of General Surgery, Yeditepe University Faculty of Medicine, Istanbul, Turkey., Soma D; Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana; Division of Transplantation & Hepatobiliary Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida., Aksu E; Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana., Lopez K; Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana., Park Y; Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana., Cross-Najafi A; Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana., Li P; Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana., Kundu D; Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana; Division of Research, Richard L. Roudebush VA Medical Center, Indianapolis, Indiana., House MG; Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana., Chakraborty S; Department of Medical Physiology, Texas A&M University College of Medicine, Bryan, Texas., Glaser S; Department of Medical Physiology, Texas A&M University College of Medicine, Bryan, Texas., Kennedy L; Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana; Division of Research, Richard L. Roudebush VA Medical Center, Indianapolis, Indiana., Francis H; Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana; Division of Research, Richard L. Roudebush VA Medical Center, Indianapolis, Indiana., Zhang W; Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana., Alpini G; Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana; Division of Research, Richard L. Roudebush VA Medical Center, Indianapolis, Indiana., Ekser B; Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana. Electronic address: bekser@iupui.edu.
Publikováno v:
The American journal of pathology [Am J Pathol] 2022 Sep; Vol. 192 (9), pp. 1200-1217. Date of Electronic Publication: 2022 May 28.