Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Arthur‐Donny Strosberg"'
Publikováno v:
Viruses, Vol 2, Iss 8, Pp 1734-1751 (2010)
Hepatitis C virus (HCV) infects over 130 million people worldwide and is a major cause of liver disease. No vaccine is available. Novel specific drugs for HCV are urgently required, since the standard-of-care treatment of pegylated interferon combine
Externí odkaz:
https://doaj.org/article/62991a4e0c244d5fa871a2d44ce03f2d
Publikováno v:
The Journal of General Virology
Hepatitis C virus (HCV) infects over 130 million people causing a worldwide epidemic of liver cirrhosis and hepatocellular-carcinoma. Because current HCV treatments are only partially effective, molecular mechanisms involved in HCV propagation are ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e25d3479b7bd8c86088c4a1a03e40a
http://europepmc.org/articles/PMC3052529
http://europepmc.org/articles/PMC3052529
Autor:
John A. Porco, John K. Snyder, Timothy P. Spicer, Aaron B. Beeler, Peter Hodder, Louis Scampavia, Arthur Donny Strosberg, Virginia Takahashi, Smitha Kota
Publikováno v:
ASSAY and Drug Development Technologies. 8:96-105
Binding of hepatitis C virus (HCV) RNA to core, the capsid protein, results in the formation of the nucleocapsid, the first step in the assembly of the viral particle. A novel assay was developed to discover small molecule inhibitors of core dimeriza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f801fb118978ba9fd5ec355b759d78
https://doi.org/10.1089/adt.2009.0217
https://doi.org/10.1089/adt.2009.0217
Publikováno v:
Acta Medica Scandinavica. 221:107-110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea1cef8f59281c3e77ed21ff411145cb
https://doi.org/10.1111/j.0954-6820.1987.tb09910.x
https://doi.org/10.1111/j.0954-6820.1987.tb09910.x
Autor:
Vladimir Zilberfarb, Melissa Kazantzis, Lotfi Chouchane, Remy Thomas, Konduru S Sastry, Daniel Tews, Mouaadh Abdelkarim, Andrea Guennoun, Martin Wabitsch, Arthur Donny Strosberg
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, BioMed Central, 2015, 13 (1), pp.135. 〈10.1186/s12967-015-0480-6〉
Journal of Translational Medicine, BioMed Central, 2015, 13 (1), pp.135. ⟨10.1186/s12967-015-0480-6⟩
Journal of Translational Medicine, 2015, 13 (1), pp.135. ⟨10.1186/s12967-015-0480-6⟩
Journal of Translational Medicine, BioMed Central, 2015, 13 (1), pp.135. 〈10.1186/s12967-015-0480-6〉
Journal of Translational Medicine, BioMed Central, 2015, 13 (1), pp.135. ⟨10.1186/s12967-015-0480-6⟩
Journal of Translational Medicine, 2015, 13 (1), pp.135. ⟨10.1186/s12967-015-0480-6⟩
Background Functional brown adipose tissue (BAT), involved in energy expenditure, has recently been detected in substantial amounts in adults. Formerly overlooked BAT has now become an attractive anti-obesity target. Methods and results Molecular cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15efe123897eb7f206b685bb3bec9f2
http://www.hal.inserm.fr/inserm-01264507/document
http://www.hal.inserm.fr/inserm-01264507/document
Autor:
Bernard Bailleul, Julian G. Mercer, Kim-Marie Moar, Philippe Froguel, Nigel Hoggard, Arthur Donny Strosberg
Publikováno v:
Journal of Neuroendocrinology. 12:649-655
Leptin receptor (OB-R) splice variants either encode proteins with different 3' cytoplasmic domains or have different 5' untranslated regions (UTR), indicative of dual promoters. The B219/OB-R promoter transcribes only OB-R transcripts, whereas the O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b57a212fc1e72f9c295458b7b60a7c12
https://doi.org/10.1046/j.1365-2826.2000.00501.x
https://doi.org/10.1046/j.1365-2826.2000.00501.x
Publikováno v:
Endocrinology. 142:4264-4271
Several reports have demonstrated that the pineal hormone, melatonin, plays an important role in body mass regulation in mammals. To date, however, the target tissues and relevant biochemical mechanisms involved remain uncharacterized. As adipose tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3753f17b65a109e5a4569454e9aeb930
https://doi.org/10.1210/endo.142.10.8423
https://doi.org/10.1210/endo.142.10.8423
Publikováno v:
Molecular and Cellular Endocrinology. 175:81-92
In addition to their role in inflammation, cytokines like TNFalpha have been reported to regulate the adipose tissue function suggesting a role for these soluble mediators in metabolism. However, it is not known whether adipocytes have the capacity t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8ea1350d0c7ce048932386e35239f9
https://doi.org/10.1016/s0303-7207(01)00394-x
https://doi.org/10.1016/s0303-7207(01)00394-x
Publikováno v:
Diabetologia. 44:377-386
Adipose tissue-derived tumour necrosis factor-alpha (TNF-alpha) has been implicated in the insulin resistance observed in animal models of obesity. Moreover, TNF-alpha has inhibitory effects on adipocyte differentiation. Glucocorticoids play importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630b5aa3b574492d1eae2e6d7fad65c5
https://doi.org/10.1007/s001250051630
https://doi.org/10.1007/s001250051630
Autor:
Andrew Anthony, Arthur Donny Strosberg, RE Pounder, J L Guillaume, Rosalind Sim, Andrew J. Wakefield, Amar P. Dhillon
Publikováno v:
Alimentary Pharmacology & Therapeutics. 14:579-585
Background: We previously localized β3-adrenergic receptors immunohistochemically in human gastrointestinal smooth muscle and incidently found a population of human pancreatic islet cells and duodenal epithelial neuroendocrine cells that also expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::182949e35a8beea2a4fe8489ff7d1881
https://doi.org/10.1046/j.1365-2036.2000.00722.x
https://doi.org/10.1046/j.1365-2036.2000.00722.x