Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Artemotil"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:1436-1441
A series of artemisinin derived esters 7a–j, incorporating pharmacologically privileged substructure, such as biphenyl, adamantane and fluorene, have been prepared and evaluated for antimalarial activity against multidrug-resistant (MDR) Plasmodium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c673c9af7d6f8775ccf02618fc809a31
https://doi.org/10.1016/j.bmcl.2007.12.074
https://doi.org/10.1016/j.bmcl.2007.12.074
Autor:
Sornchai Looareesuwan, Polrat Wilairatana, Charles B. Lugt, Qigui Li, Wilbur K. Milhous, Suparp Vannaphan, Kobsiri Chalearmrult, Srivicha Krudsood
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 71:723-731
Pharmacokinetic data were obtained to evaluate the therapeutic potential of Artemotil (beta-arteether) in 56 Thai patients with severe Plasmodium falciparum malaria. Intramuscular administration was given at 1) a low dose of 3.2 mg/kg on day 0 and 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bdde1606bad92e4ad60327fc95e5ada
https://doi.org/10.4269/ajtmh.2004.71.723
https://doi.org/10.4269/ajtmh.2004.71.723
Akademický článek
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Autor:
Ch. B. Lugt, P. A. M. Peeters, Polrat Wilairatana, Sornchai Looareesuwan, Frans A. E. Sollie, B. M. Schilizzi, James O. Peggins, B. Oosterhuis, Srivicha Krudsood
Publikováno v:
British Journal of Clinical Pharmacology. 53:492-500
Aims The antimalarial efficacy/pharmacodynamics and pharmacokinetics of intramuscular (i.m.) artemotil in Thai patients with acute uncomplicated falciparum malaria were studied to determine effective dose regimens and to compare these with the standa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58812b795f8e04ee845527130e449e87
https://doi.org/10.1046/j.1365-2125.2002.01590.x
https://doi.org/10.1046/j.1365-2125.2002.01590.x
Autor:
Charles Nsangou, Bonaventure Jemea, L.E. Kouemeni, Elie Mbonda, Tetanye Ekoe, Felix Tietche, Georgette Guemkam, Roger Moyou-Somo, Martin Ondoa
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 64:229-232
One hundred and two children aged 0-10 years with cerebral malaria (Blantyre coma score of 2 or less) were randomly treated either with intramuscular arteether (3.2 mg/kg on Day 0, followed by 1.6 mg/kg on Days 1 to 4) or intravenous (i.v.) quinine d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f631363caae0ac559b55fc765c73b3a2
https://doi.org/10.4269/ajtmh.2001.64.229
https://doi.org/10.4269/ajtmh.2001.64.229
Autor:
Isabelle M. Medana, R. O. Weller, Gareth D. H. Turner, Tran Tinh Hien, W. F. Blakemore, J. B. Cavanagh, Nicholas J. White, A. Dayan, D. Bethell, N.P.J. Day, N. T. H. Mai, Nh H. Phu
Publikováno v:
Lancet (London, England). 362(9380)
Summary In animals, high doses of intramuscular artemether and artemotil have been shown to cause an unusual pattern of selective damage to certain brainstem nuclei, especially those implicated in hearing and balance. We aimed to investigate whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee03ccd32816fa18f9e3c4f854a11e79
https://pubmed.ncbi.nlm.nih.gov/12892962
https://pubmed.ncbi.nlm.nih.gov/12892962
Autor:
P. A. M. Peeters, C. Osborne, V. R. Gordeuk, C. B. Lugt, Philip E. Thuma, G. F. Mabeza, B. Oosterhuis, Godfrey Biemba, G. M. Shakankale, G. J. Bhat
Publikováno v:
The American journal of tropical medicine and hygiene. 62(4)
The efficacy and safety of intramuscular artemotil (ARTECEF) was compared to intravenous quinine in African children with cerebral malaria. This prospective block randomized open-label study was conducted at two centers in Zambia. Subjects were child
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd3288e526782f09ae35f328856eee3
https://pubmed.ncbi.nlm.nih.gov/11220772
https://pubmed.ncbi.nlm.nih.gov/11220772
Publikováno v:
Clinical pharmacokinetics. 39(4)
Various compounds of the artemisinin family are currently used for the treatment of patients with malaria worldwide. They are characterised by a short half-life and feature the most rapidly acting antimalarial drugs to date. They are increasingly bei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b26c1ae2113a5788f1cbb24c1fe789
https://pubmed.ncbi.nlm.nih.gov/11069212
https://pubmed.ncbi.nlm.nih.gov/11069212
Akademický článek
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Akademický článek
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