Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Artemisone"'
Publikováno v:
Virus Research, Vol 349, Iss , Pp 199448- (2024)
Adenoviral infections, particularly in children, remain a significant public health issue with no approved targeted treatments. Artemisinin and its derivatives, well-known for their use in malaria treatment, have shown antiviral activities in recent
Externí odkaz:
https://doaj.org/article/2addc8d113b34be0b621b1cb4b74f1ce
Autor:
Daniel J. Watson, Lizahn Laing, Jacobus P. Petzer, Ho Ning Wong, Christopher J. Parkinson, Lubbe Wiesner, Richard K. Haynes
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Efforts to develop new artemisinin triple combination therapies effective against artemisinin-tolerant strains of Plasmodium falciparum based on rational combinations comprising artemisone or other amino-artemisinins, a redox active drug and a third
Externí odkaz:
https://doaj.org/article/f0b32b20533b40e5ab69e8781098f068
Akademický článek
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Autor:
Jerome P. L. Ng, Yu Han, Li Jun Yang, Lyn-Marie Birkholtz, Dina Coertzen, Ho Ning Wong, Richard K. Haynes, Paolo Coghi, Vincent Kam Wai Wong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Artemisinin, isolated from the traditional Chinese medicinal plant qīng hāo 青蒿 (Artemisia annua) and its derivatives are used for treatment of malaria. With treatment failures now being recorded for the derivatives and companion drugs used in a
Externí odkaz:
https://doaj.org/article/b5bdae38dcd7468283dd4e8dfca5fc88
Autor:
Ho Ning Wong, Angélique Lewies, Michaela Haigh, Joe M. Viljoen, Johannes F. Wentzel, Richard K. Haynes, Lissinda H. du Plessis
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The most frequently occurring cancers are those of the skin, with melanoma being the leading cause of death due to skin cancer. Breakthroughs in chemotherapy have been achieved in certain cases, though only marginal advances have been made in treatme
Externí odkaz:
https://doaj.org/article/a147c80b580b4adda0bcafb538ce44d8
Autor:
Jacob Golenser, Nadeen Salaymeh, Abd Alroof Higazi, Mohammed Alyan, Mahran Daif, Ron Dzikowski, Abraham J. Domb
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Malaria caused by Plasmodium falciparum causes numerous cases of morbidity with about 400,000 deaths yearly owing, mainly, to inflammation leading to cerebral malaria (CM). CM conventionally is treated by repetitive administration of anti-plasmodial
Externí odkaz:
https://doaj.org/article/b5c043a1220e4f5da4bc6b65a7ea7468
Autor:
Johanna Zech, Daniel Gold, Nadeen Salaymeh, Netanel Cohen Sasson, Ithai Rabinowitch, Jacob Golenser, Karsten Mäder
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 509 (2020)
Artemisone is an innovative artemisinin derivative with applications in the treatment of malaria, schistosomiasis and other diseases. However, its low aqueous solubility and tendency to degrade after solubilisation limits the translation of this drug
Externí odkaz:
https://doaj.org/article/5f02261ffc5646efa196de665ffa3b3d
Akademický článek
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Autor:
Yuet Wu, Silvia Parapini, Ian D. Williams, Paola Misiano, Ho Ning Wong, Donatella Taramelli, Nicoletta Basilico, Richard K. Haynes
Publikováno v:
Molecules, Vol 23, Iss 7, p 1713 (2018)
According to the precepts that C-10 amino-artemisinins display optimum biological activities for the artemisinin drug class, and that attachment of a sugar enhances specificity of drug delivery, polarity and solubility so as to attenuate toxicity, we
Externí odkaz:
https://doaj.org/article/b517221cd3f7487bac373f6cbbd2101b