Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Artem Sokolov"'
Autor:
Irzam Sarfraz, Yichen Wang, Amulya Shastry, Wei Kheng Teh, Artem Sokolov, Brian R. Herb, Heather H. Creasy, Isaac Virshup, Ruben Dries, Kylee Degatano, Anup Mahurkar, Daniel J. Schnell, Pedro Madrigal, Jason Hilton, Nils Gehlenborg, Timothy Tickle, Joshua D. Campbell
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Many datasets are being produced by consortia that seek to characterize healthy and disease tissues at single-cell resolution. While biospecimen and experimental information is often captured, detailed metadata standards related to data matr
Externí odkaz:
https://doaj.org/article/878df33f65034434a42db96816edbe92
Autor:
Marie-Laure Charpignon, Bella Vakulenko-Lagun, Bang Zheng, Colin Magdamo, Bowen Su, Kyle Evans, Steve Rodriguez, Artem Sokolov, Sarah Boswell, Yi-Han Sheu, Melek Somai, Lefkos Middleton, Bradley T. Hyman, Rebecca A. Betensky, Stan N. Finkelstein, Roy E. Welsch, Ioanna Tzoulaki, Deborah Blacker, Sudeshna Das, Mark W. Albers
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Previous observational studies of the diabetes drugs metformin vs. sulfonylureas have yielded mixed results about whether metformin reduces the risk of dementia, relative to the sulfonylureas. Here, the authors apply a novel competing risks approach
Externí odkaz:
https://doaj.org/article/6c6653ae33484933bc4f68d1094c553c
Autor:
Sonia Pernas, Jennifer L. Guerriero, Sergey Naumenko, Shom Goel, Meredith M. Regan, Jiani Hu, Beth T. Harrison, Filipa Lynce, Nancy U. Lin, Ann Partridge, Aki Morikawa, John Hutchinson, Elizabeth A. Mittendorf, Artem Sokolov, Beth Overmoyer
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Inflammatory breast cancer (IBC) is a rare and understudied disease, with 40% of cases presenting with human epidermal growth factor receptor 2 (HER2)-positive subtype. The goals of this study were to (i) assess the pathologic complete re
Externí odkaz:
https://doaj.org/article/021e9fa4372f4e9eb84818ae8ea438b8
Autor:
Steve Rodriguez, Clemens Hug, Petar Todorov, Nienke Moret, Sarah A. Boswell, Kyle Evans, George Zhou, Nathan T. Johnson, Bradley T. Hyman, Peter K. Sorger, Mark W. Albers, Artem Sokolov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Clinical trials of novel therapeutics for Alzheimer’s Disease (AD) have provided largely negative results, so far. Here, the authors present a machine learning framework that quantifies potential associations between the pathology of AD severity an
Externí odkaz:
https://doaj.org/article/93e763bd3055417ea9c559a7b6fa24d5
Autor:
Artem Sokolov
Publikováno v:
Международная аналитика, Vol 0, Iss 1-2, Pp 41-51 (2019)
The article is devoted to the influence of the American military presence in Germany on the foreign policy strategy of the German leadership in the matter of ensuring the security of Germany. The location of the US Army in a number of German lands ha
Externí odkaz:
https://doaj.org/article/b8554d2caf87419b93ef7ed7d50447c1
Autor:
Camila Ferreira de Souza, Thais S. Sabedot, Tathiane M. Malta, Lindsay Stetson, Olena Morozova, Artem Sokolov, Peter W. Laird, Maciej Wiznerowicz, Antonio Iavarone, James Snyder, Ana deCarvalho, Zachary Sanborn, Kerrie L. McDonald, William A. Friedman, Daniela Tirapelli, Laila Poisson, Tom Mikkelsen, Carlos G. Carlotti, Jr., Steven Kalkanis, Jean Zenklusen, Sofie R. Salama, Jill S. Barnholtz-Sloan, Houtan Noushmehr
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 637-651 (2018)
Summary: Glioma diagnosis is based on histomorphology and grading; however, such classification does not have predictive clinical outcome after glioblastomas have developed. To date, no bona fide biomarkers that significantly translate into a surviva
Externí odkaz:
https://doaj.org/article/706cab09ad454b2da0b587fe71e18729
Autor:
Artem Sokolov, Stephanie Ashenden, Nil Sahin, Richard Lewis, Nurdan Erdem, Elif Ozaltan, Andreas Bender, Frederick P. Roth, Murat Cokol
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Mutations in ATP Binding Cassette (ABC)-transporter genes can have major effects on the bioavailability and toxicity of the drugs that are ABC-transporter substrates. Consequently, methods to predict if a drug is an ABC-transporter substrate are usef
Externí odkaz:
https://doaj.org/article/736150f4c8f3474baf24050430ee351d
Publikováno v:
Metals, Vol 11, Iss 2, p 321 (2021)
Research into the solvent extraction of iron(III) from a chloride solution after bauxite HCl leaching by neutral oxygen-containing extractants and their mixtures were studied and the iron(III) extraction degree from chloride solutions using alcohols
Externí odkaz:
https://doaj.org/article/c6834ae2205440d2aca8d0f0f413226a
Autor:
Daniel E Carlin, Evan O Paull, Kiley Graim, Christopher K Wong, Adrian Bivol, Peter Ryabinin, Kyle Ellrott, Artem Sokolov, Joshua M Stuart
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0170340 (2017)
We introduce a novel method called Prophetic Granger Causality (PGC) for inferring gene regulatory networks (GRNs) from protein-level time series data. The method uses an L1-penalized regression adaptation of Granger Causality to model protein levels
Externí odkaz:
https://doaj.org/article/907adac8d9b04f14a7305265e16cb304
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 3, p e1004790 (2016)
We present a novel regularization scheme called The Generalized Elastic Net (GELnet) that incorporates gene pathway information into feature selection. The proposed formulation is applicable to a wide variety of problems in which the interpretation o
Externí odkaz:
https://doaj.org/article/5043eea87f2b48a49e403eee395d55ab