Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Artem Gridnev"'
Autor:
Hui Chen, Artem Gridnev, Netanya Schlamowitz, Wanyi Hu, Kuntala Dey, Guangrong Zheng, Jyoti R. Misra
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37829- (2024)
The transcription factors, TEAD1-4 together with their co-activator YAP/TAZ function as key downstream effectors of the Hippo pathway. Hyperactivation of TEAD-YAP/TAZ activity is observed in many human cancers. TEAD1-4 possess distinct physiological
Externí odkaz:
https://doaj.org/article/04f8c3a78de34b3d8febf7c018afff4d
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The paralogous oncogenic transcriptional coactivators YAP and TAZ are the distal effectors of the Hippo signaling pathway, which plays a critical role in cell proliferation, survival and cell fate specification. They are frequently deregulated in mos
Externí odkaz:
https://doaj.org/article/1d6482387d174a3f8c9e7eefcb9ca425
Autor:
Artem Gridnev, Jyoti R. Misra
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Dachsous (Ds) and Fat are evolutionarily conserved cell adhesion molecules that play a critical role in development of multiple organ systems, where they coordinate tissue growth and morphogenesis. Much of our understanding of Ds-Fat signaling pathwa
Externí odkaz:
https://doaj.org/article/c250806d6a1842869a7d2e33a3b18314
Autor:
Artem Gridnev, Jyoti R. Misra
Publikováno v:
Frontiers in cell and developmental biology. 10
Dachsous (Ds) and Fat are evolutionarily conserved cell adhesion molecules that play a critical role in development of multiple organ systems, where they coordinate tissue growth and morphogenesis. Much of our understanding of Ds-Fat signaling pathwa
Publikováno v:
Cancers. 14:1029
YAP/TAZ are transcriptional coactivators that function as the key downstream effectors of Hippo signaling. They are commonly misregulated in most human cancers, which exhibit a higher level of expression and nuclear localization of YAP/TAZ, and displ