Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Artem A. Astafev"'
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109483- (2024)
Summary: Sexual dimorphism affects various aspects of physiology, metabolism and longevity. Circadian clock is a master regulator of metabolism. Anti-aging dietary interventions reprogram circadian transcriptome in the liver and other tissues, but li
Externí odkaz:
https://doaj.org/article/67a7f20b67124a3ebd3d43956d8ed167
Autor:
Irina A. Pikuleva, Erin Prendergast, Tung Dao, Aicha Saadane, Ilya Bederman, Emmy Schwarz, Artem A. Astafev, Alexey M. Petrov, Natalia Mast, Nicole El-Darzi
Publikováno v:
Cellular and Molecular Life Sciences. 78:963-983
Apolipoprotein D (APOD) is an atypical apolipoprotein with unknown significance for retinal structure and function. Conversely, apolipoprotein E (APOE) is a typical apolipoprotein with established roles in retinal cholesterol transport. Herein, we im
Autor:
Kaitlyn N. Lewis, Roman V. Kondratov, Soumyaditya Ghosh, Artem A. Astafev, Rochelle Buffenstein, Richa Tulsian
Publikováno v:
FASEB J
Light is the key regulator of circadian clock, the time-keeping system synchronizing organism physiology and behavior with environmental day and night conditions. In its natural habitat, the strictly subterranean naked mole-rat (Heterocephalus glaber
Autor:
Kuldeep Makwana, Roman V. Kondratov, Volha Mezhnina, Ryan W. Pearce, Yana Sandlers, Allan Poe, Oghogho P Ebeigbe, Artem A. Astafev, Nikkhil Velingkaar
Publikováno v:
Aging Cell
Calorie restriction (CR), an age delaying diet, affects fat oxidation through poorly understood mechanisms. We investigated the effect of CR on fat metabolism gene expression and intermediate metabolites of fatty acid oxidation in the liver. We found
Autor:
Nicole, El-Darzi, Natalia, Mast, Alexey M, Petrov, Tung, Dao, Artem A, Astafev, Aicha, Saadane, Erin, Prendergast, Emmy, Schwarz, Ilya, Bederman, Irina A, Pikuleva
Publikováno v:
Cell Mol Life Sci
Apolipoprotein D (APOD) is an atypical apolipoprotein with unknown significance for retinal structure and function. Conversely, apolipoprotein E (APOE) is a typical apolipoprotein with established roles in retinal cholesterol transport. Herein, we im
Autor:
Aicha Saadane, Irina A. Pikuleva, Alexey M. Petrov, Natalia Mast, Artem A. Astafev, Nicole El-Darzi
Publikováno v:
Biomolecules
Volume 9
Issue 12
Volume 9
Issue 12
In mammalian retina, cholesterol excess is mainly metabolized to oxysterols by cytochromes P450 27A1 (CYP27A1) and 46A1 (CYP46A1) or removed on lipoprotein particles containing apolipoprotein E (APOE). In contrast, esterification by sterol-O-acyltran
Autor:
Aicha Saadane, Natalia Mast, Morrie Lam, Nicole El-Darzi, Irina A. Pikuleva, Artem A. Astafev
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology, Vol 9 (2018)
N,N-dimethyl-3β-hydroxycholenamide (DMHCA) is an experimental pharmaceutical and a steroidal liver X receptor (LXR) agonist, which does not induce undesired hepatic lipogenesis. Herein, DMHCA was evaluated for its retinal effects on normal C57BL/6J
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports
Scientific Reports
The rhythms in the expression of circadian clock genes are affected by calorie restriction (CR), a dietary paradigm known to increase lifespan. Many physiological effects of CR differ between males and females; here we investigated if the sex of anim
Autor:
Bagheri A; Department of Biological, Geological and Environmental Sciences (BGES), Cleveland State University, Cleveland, OH 44115, USA.; Center for Gene Regulation in Health and Disease (GRHD), Cleveland State University, Cleveland, OH 44115, USA., Astafev A; Department of Biological, Geological and Environmental Sciences (BGES), Cleveland State University, Cleveland, OH 44115, USA.; Center for Gene Regulation in Health and Disease (GRHD), Cleveland State University, Cleveland, OH 44115, USA., Al-Hashimy T; Department of Biological, Geological and Environmental Sciences (BGES), Cleveland State University, Cleveland, OH 44115, USA., Jiang P; Department of Biological, Geological and Environmental Sciences (BGES), Cleveland State University, Cleveland, OH 44115, USA.; Center for Gene Regulation in Health and Disease (GRHD), Cleveland State University, Cleveland, OH 44115, USA.; Center for Applied Data Analysis and Modeling (ADAM), Cleveland State University, Cleveland, OH 44115, USA.; Center for RNA Science and Therapeutics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Publikováno v:
Cells [Cells] 2022 Sep 23; Vol. 11 (19). Date of Electronic Publication: 2022 Sep 23.
Autor:
Mezhnina V; Center for Gene Regulation in Health and Disease and Department of Biological Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA., Pearce R; Department of Chemistry, Cleveland State University, Cleveland, Ohio, USA., Poe A; Center for Gene Regulation in Health and Disease and Department of Biological Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA., Velingkaar N; Center for Gene Regulation in Health and Disease and Department of Biological Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA., Astafev A; Center for Gene Regulation in Health and Disease and Department of Biological Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA., Ebeigbe OP; Center for Gene Regulation in Health and Disease and Department of Biological Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA., Makwana K; Center for Gene Regulation in Health and Disease and Department of Biological Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA., Sandlers Y; Department of Chemistry, Cleveland State University, Cleveland, Ohio, USA., Kondratov RV; Center for Gene Regulation in Health and Disease and Department of Biological Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA.
Publikováno v:
Aging cell [Aging Cell] 2020 Nov; Vol. 19 (11), pp. e13266. Date of Electronic Publication: 2020 Oct 26.