Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Art F Y Poon"'
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 11, p e1010745 (2022)
Clusters of genetically similar infections suggest rapid transmission and may indicate priorities for public health action or reveal underlying epidemiological processes. However, clusters often require user-defined thresholds and are sensitive to no
Externí odkaz:
https://doaj.org/article/67112e635a2a48d4927fd8683a38d966
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 11, p e1010649 (2022)
Externí odkaz:
https://doaj.org/article/52b815c5ad26441aa90adf6a7bbbb0d1
Autor:
Laura Muñoz-Baena, Art F Y Poon
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010331 (2022)
Gene overlap occurs when two or more genes are encoded by the same nucleotides. This phenomenon is found in all taxonomic domains, but is particularly common in viruses, where it may increase the information content of compact genomes or influence th
Externí odkaz:
https://doaj.org/article/66d9c00919564226bc190594146b85c4
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0259877 (2021)
The shape of phylogenetic trees can be used to gain evolutionary insights. A tree's shape specifies the connectivity of a tree, while its branch lengths reflect either the time or genetic distance between branching events; well-known measures of tree
Externí odkaz:
https://doaj.org/article/e17a4155de8c456d83047b21a9fbb94e
Autor:
Rosemary M McCloskey, Art F Y Poon
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 11, p e1005868 (2017)
Clustering infections by genetic similarity is a popular technique for identifying potential outbreaks of infectious disease, in part because sequences are now routinely collected for clinical management of many infections. A diverse number of nonpar
Externí odkaz:
https://doaj.org/article/2859b34a889b40ac97a89b093e6babf6
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 7, p e1004763 (2016)
Externí odkaz:
https://doaj.org/article/6dd08e874cb2407b9f578d870ba9948a
Autor:
Laura A Cotton, Xiaomei T Kuang, Anh Q Le, Jonathan M Carlson, Benjamin Chan, Denis R Chopera, Chanson J Brumme, Tristan J Markle, Eric Martin, Aniqa Shahid, Gursev Anmole, Philip Mwimanzi, Pauline Nassab, Kali A Penney, Manal A Rahman, M-J Milloy, Martin T Schechter, Martin Markowitz, Mary Carrington, Bruce D Walker, Theresa Wagner, Susan Buchbinder, Jonathan Fuchs, Beryl Koblin, Kenneth H Mayer, P Richard Harrigan, Mark A Brockman, Art F Y Poon, Zabrina L Brumme
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004295 (2014)
HLA-restricted immune escape mutations that persist following HIV transmission could gradually spread through the viral population, thereby compromising host antiviral immunity as the epidemic progresses. To assess the extent and phenotypic impact of
Externí odkaz:
https://doaj.org/article/5120521a2c5e4e9facd0fbd9fe45093e
Autor:
David J H F Knapp, Rachel A McGovern, Art F Y Poon, Xiaoyin Zhong, Dennison Chan, Luke C Swenson, Winnie Dong, P Richard Harrigan
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99508 (2014)
Next generation, "deep", sequencing has increasing applications both clinically and in disparate fields of research. This study investigates the accuracy and reproducibility of "deep" sequencing as applied to co-receptor prediction using the V3 loop
Externí odkaz:
https://doaj.org/article/c0b72ccbb0704d3b9e09eeee2cdcd6aa
Autor:
Ocean Thakali, Élisabeth Mercier, Walaa Eid, Martin Wellman, Julia Brasset-Gorny, Alyssa K. Overton, Jennifer J. Knapp, Douglas Manuel, Trevor C. Charles, Lawrence Goodridge, Eric J. Arts, Art F. Y. Poon, R. Stephen Brown, Tyson E. Graber, Robert Delatolla, Christopher T. DeGroot, Ontario Wastewater Surveillance Consortium
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Wastewater surveillance of coronavirus disease 2019 (COVID-19) commonly applies reverse transcription-quantitative polymerase chain reaction (RT-qPCR) to quantify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA concentration
Externí odkaz:
https://doaj.org/article/bc74bea4a03940bd85b38f29b9ec9203
Autor:
Art F Y Poon, Lorne W Walker, Heather Murray, Rosemary M McCloskey, P Richard Harrigan, Richard H Liang
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78122 (2013)
A phylogeny is a tree-based model of common ancestry that is an indispensable tool for studying biological variation. Phylogenies play a special role in the study of rapidly evolving populations such as viruses, where the proliferation of lineages is
Externí odkaz:
https://doaj.org/article/7479234c6c74419eb64496a53b185d52