Mapping Aldehyde Dehydrogenase 1A1 activity using an [18F]Substrate-based approach

Autor: Pereira, R., Gendron, T., Sanghera, C., Greenwood, H.E., Newcombe, J., McCormick, P.N., Sander, K., Topf, Maya, Arstad, E., Witney, T.H.

Aldehyde dehydrogenases (ALDHs) catalyze the oxidation of aldehydes to carboxylic acids. Elevated ALDH expression in human cancers is linked to metastases and poor overall survival. Despite ALDH being a poor prognostic factor, the non-invasive assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::3e442c0a958587f72a066da64956dcdd
https://eprints.bbk.ac.uk/id/eprint/26171/2/Pereira_et_al-2019-Chemistry_-_A_European_Journal.pdf

Imaging tau pathology in Alzheimer's disease with positron emission tomography: lessons learned from imaging-neuropathology validation studies.

Autor: Moscoso A; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden., Wren MC; Department of Imaging, Centre for Radiopharmaceutical Chemistry, University College London, London, UK.; Department of Chemistry, University College London, London, UK.; Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, Queen Square Institute of Neurology, University College London, London, UK.; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK., Lashley T; Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, Queen Square Institute of Neurology, University College London, London, UK.; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK., Arstad E; Department of Imaging, Centre for Radiopharmaceutical Chemistry, University College London, London, UK.; Department of Chemistry, University College London, London, UK., Murray ME; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Fox NC; Dementia Research Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK.; UK Dementia Research Institute, Queen Square Institute of Neurology, University College London, London, UK., Sander K; Department of Imaging, Centre for Radiopharmaceutical Chemistry, University College London, London, UK.; Department of Chemistry, University College London, London, UK., Schöll M; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. michael.scholl@neuro.gu.se.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden. michael.scholl@neuro.gu.se.; Dementia Research Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK. michael.scholl@neuro.gu.se.; Department of Clinical Physiology, Sahlgrenska University Hospital, Röda stråket 10B, 413 45, Gothenburg, Sweden. michael.scholl@neuro.gu.se.

Publikováno v: Molecular neurodegeneration [Mol Neurodegener] 2022 Jun 03; Vol. 17 (1), pp. 39. Date of Electronic Publication: 2022 Jun 03.

Seizures Triggered by Systemic Administration of 4-Aminopyridine in Rats Lead to Acute Brain Glucose Hypometabolism, as Assessed by [ 18 F]FDG PET Neuroimaging.

Autor: Gómez-Oliver, Francisca^1,2,3 (AUTHOR) gomezof@ucm.es, Fernández de la Rosa, Rubén^1,4 (AUTHOR) rufernan@ucm.es, Brackhan, Mirjam^1,3 (AUTHOR) brackhanm@gmail.com, Bascuñana, Pablo^1,3 (AUTHOR) pablo.bascunana@salud.madrid.org, Pozo, Miguel Ángel^1,3,5 (AUTHOR) pozo@ucm.es, García-García, Luis^1,2,3 (AUTHOR) lgarciag@ucm.es

Publikováno v: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 23, p12774. 15p.

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