Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Arshia Beigi"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 13, Iss 6 (2023)
AbstractThe micronutrient vitamin B12 is an essential cofactor for two enzymes: methionine synthase, which plays a key role in the one-carbon cycle; and methylmalonyl-CoA mutase, an enzyme in a pathway that breaks down branched-chain amino acids and
Externí odkaz:
https://doaj.org/article/d8b4d07516ac4ef4b19a9e188dc45268
Publikováno v:
Current Oncology, Vol 28, Iss 5, Pp 3812-3824 (2021)
Background: Real-world data on palliative systemic therapies (PST) in treating metastatic bladder cancer (mBC) is limited. This study investigates current trends in treating mBC with first- (1L) and second-line (2L) chemotherapy (CT) and immunotherap
Externí odkaz:
https://doaj.org/article/dd4ae11a7bae49ccab5897bb75afe73b
Autor:
Dongyeop Lee, Seon Woo A An, Yoonji Jung, Yasuyo Yamaoka, Youngjae Ryu, Grace Ying Shyen Goh, Arshia Beigi, Jae-Seong Yang, Gyoo Yeol Jung, Dengke K Ma, Chang Man Ha, Stefan Taubert, Youngsook Lee, Seung-Jae V Lee
Publikováno v:
PLoS Biology, Vol 17, Iss 8, p e3000415 (2019)
Low temperatures delay aging and promote longevity in many organisms. However, the metabolic and homeostatic aspects of low-temperature-induced longevity remain poorly understood. Here, we show that lipid homeostasis regulated by Caenorhabditis elega
Externí odkaz:
https://doaj.org/article/a87c878b580e45cd83bfa66a2646930b
Autor:
Alexander W. Wyatt, Kim N. Chi, Daniel Khalaf, Matti Annala, Kevin Beja, Elena Schönlau, Arshia Beigi, Arkhjamil Angeles, Nicolette M. Fonseca, Gillian Vandekerkhove, Andrew J. Murtha, Elie Ritch, Gang Wang, Amanda Wong, Steven Yip, Simon Fu, Cameron Herberts, Evan Warner
Purpose:DNA damage repair (DDR) defects are common across cancer types and can indicate therapeutic vulnerability. Optimal exploitation of DDR defects in prostate cancer requires new diagnostic strategies and a better understanding of associated clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4473477859916eea8ed787ed187d7010
https://doi.org/10.1158/1078-0432.c.6530568.v1
https://doi.org/10.1158/1078-0432.c.6530568.v1
Autor:
Alexander W. Wyatt, Kim N. Chi, Daniel Khalaf, Matti Annala, Kevin Beja, Elena Schönlau, Arshia Beigi, Arkhjamil Angeles, Nicolette M. Fonseca, Gillian Vandekerkhove, Andrew J. Murtha, Elie Ritch, Gang Wang, Amanda Wong, Steven Yip, Simon Fu, Cameron Herberts, Evan Warner
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f3448ca1bbd5c0f7a69fed7ef2ee11
https://doi.org/10.1158/1078-0432.22480959.v1
https://doi.org/10.1158/1078-0432.22480959.v1
Autor:
Alexander W. Wyatt, Kim N. Chi, Daniel Khalaf, Matti Annala, Kevin Beja, Elena Schönlau, Arshia Beigi, Arkhjamil Angeles, Nicolette M. Fonseca, Gillian Vandekerkhove, Andrew J. Murtha, Elie Ritch, Gang Wang, Amanda Wong, Steven Yip, Simon Fu, Cameron Herberts, Evan Warner
Supplementary Figures S1-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7f0b1b76b80dc400ba706d67f347b3
https://doi.org/10.1158/1078-0432.22480962.v1
https://doi.org/10.1158/1078-0432.22480962.v1
Autor:
Alexander W. Wyatt, Kim N. Chi, Daniel Khalaf, Matti Annala, Kevin Beja, Elena Schönlau, Arshia Beigi, Arkhjamil Angeles, Nicolette M. Fonseca, Gillian Vandekerkhove, Andrew J. Murtha, Elie Ritch, Gang Wang, Amanda Wong, Steven Yip, Simon Fu, Cameron Herberts, Evan Warner
Supplementary Tables S1-S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3565e30d39349f94756fc40d24f52a
https://doi.org/10.1158/1078-0432.22480956.v1
https://doi.org/10.1158/1078-0432.22480956.v1
The micronutrient vitamin B12 is an essential cofactor for two enzymes: methionine synthase, which plays a key role in the one-carbon cycle; and methylmalonyl-CoA mutase, an enzyme in a pathway that breaks down branched-chain amino acids and odd-chai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7bcbbd74fe6b877409b31bb1a095628
https://doi.org/10.1101/2022.12.16.520805
https://doi.org/10.1101/2022.12.16.520805
Autor:
Alexander W. Wyatt, Andrew J. Murtha, Arkhjamil Angeles, Arshia Beigi, Amanda Wong, Gang Wang, Steven Yip, Cameron Herberts, Daniel Khalaf, Elena Schönlau, Kevin Beja, Elie Ritch, Nicolette Fonseca, Matti Annala, Simon Yuen Fai Fu, Evan W. Warner, Kim N. Chi, Gillian Vandekerkhove
Publikováno v:
Clinical Cancer Research. 27:1650-1662
Purpose: DNA damage repair (DDR) defects are common across cancer types and can indicate therapeutic vulnerability. Optimal exploitation of DDR defects in prostate cancer requires new diagnostic strategies and a better understanding of associated cli
Autor:
Arkhjamil Angeles, Sinja Taavitsainen, Gang Wang, Amanda Wong, Evan W. Warner, Kim N. Chi, Matti Annala, Gillian Vandekerkhove, Steven Yip, Matti Nykter, Alexander W. Wyatt, Daniel Khalaf, Arshia Beigi, Elena Schönlau, Kevin Beja
Publikováno v:
Clinical Cancer Research. 26:PR09-PR09
Recent sequencing efforts have shown that genomic alterations within DNA damage repair (DDR) pathways are relatively common in metastatic prostate cancer (mPCa). Patients harboring DDR gene aberrations can respond poorly to standard-of-care androgen