Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Arshak R, Alexanian"'
Autor:
Arshak R. Alexanian, Heidi Marie Stoellinger, Virginea de Araujo Farias, Alfredo Quiñones-Hinojosa
Publikováno v:
Investigational New Drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff57dfff6658705aacbfb2d157fcf507
https://doi.org/10.1007/s10637-023-01370-7
https://doi.org/10.1007/s10637-023-01370-7
Autor:
Avonlea Brannon, Arshak R Alexanian
Publikováno v:
Medical Oncology. 39
Discoveries made over the last decade have shown that critical changes in cancer cells, such as activation of oncogenes and silencing of tumor suppressor genes are caused not only by genetic but also by epigenetic mechanisms. While epigenetic alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aeea03c00744982068e3e9271457126
https://doi.org/10.1007/s12032-022-01683-2
https://doi.org/10.1007/s12032-022-01683-2
Publikováno v:
Assay Drug Dev Technol
Migration is a key property of live cells and critical for normal development, immune response, and disease processes such as cancer metastasis and inflammation. Methods to examine cell migration are especially useful and important for a wide range o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a3a7f8aac4ab79d369fbc3b9eaae02
https://europepmc.org/articles/PMC8968842/
https://europepmc.org/articles/PMC8968842/
Autor:
Arshak R, Alexanian
Publikováno v:
Molecular and cellular biochemistry. 477(10)
During embryogenesis and further development, mammalian epigenome undergoes global remodeling, which leads to the emergence of multiple fate-restricted cell lines as well as to their further differentiation into different specialized cell types. Ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62c8bc13ef6d78197f2d9022db801325
https://pubmed.ncbi.nlm.nih.gov/35503191
https://pubmed.ncbi.nlm.nih.gov/35503191
Autor:
Arshak R, Alexanian, Avonlea, Brannon
Publikováno v:
Medical oncology (Northwood, London, England). 39(5)
Discoveries made over the last decade have shown that critical changes in cancer cells, such as activation of oncogenes and silencing of tumor suppressor genes are caused not only by genetic but also by epigenetic mechanisms. While epigenetic alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::666fa6e5846998abcca39180c94aee64
https://pubmed.ncbi.nlm.nih.gov/35478054
https://pubmed.ncbi.nlm.nih.gov/35478054
Autor:
Ryan T. Funk, Arshak R. Alexanian
Publikováno v:
Translational Research. 162:317-323
Recently, using the chemical genetics approach for cell reprogramming, via the combination of small molecule modulators of chromatin modifying enzymes, specific SMAD signaling pathways, and cyclic adenosine monophosphate levels, we have been able to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a390a70050e0c20ebbb59299d99a2ca
https://doi.org/10.1016/j.trsl.2013.08.002
https://doi.org/10.1016/j.trsl.2013.08.002
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 45:1633-1638
Advances in cell reprogramming technologies to generate patient-specific cells of a desired type will revolutionize the field of regenerative medicine. While several cell reprogramming methods have been developed over the last decades, the majority o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a936c7e60d9bcf7c4342bbbf8e687693
https://doi.org/10.1016/j.biocel.2013.04.022
https://doi.org/10.1016/j.biocel.2013.04.022
Publikováno v:
Cellular Reprogramming. 13:385-390
Recent studies suggest that cellular therapies that utilize mesenchymal stem cells (MSCs), especially ones that have been neurally induced (NI), may provide a functional benefit in a wide range of neurological disorders. Recently, we developed a new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486415e0ef901480588290d869e1df65
https://doi.org/10.1089/cell.2011.0007
https://doi.org/10.1089/cell.2011.0007
Autor:
Arshak R. Alexanian
Publikováno v:
Regenerative Medicine. 5:891-900
Background: Stem cell-based therapies to repair and replace lost neural cells are a highly promising treatment for CNS diseases. Bone marrow (BM)-derived mesenchymal stem cells (MSCs) have great potential as therapeutic agents against neurological ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c883e3556ca7ad1d3ee78aa2d02e8ee
https://doi.org/10.2217/rme.10.67
https://doi.org/10.2217/rme.10.67
Publikováno v:
Stem Cells and Development. 17:1123-1130
Mesenchymal stem cell (MSC)-mediated tissue regeneration is a promising strategy to treat several neurodegenerative diseases and traumatic injuries of the central nervous system. Bone marrow MSCs have great potential as therapeutic agents, since they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32803f467daf42352daaa3a30191194a
https://doi.org/10.1089/scd.2007.0212
https://doi.org/10.1089/scd.2007.0212