Synthetic approaches for the synthesis of a cytostatic steroidal B–D bilactam

Autor: Koutsourea, Anna I., Arsenou, Evaggelia S., Fousteris, Manolis A., Nikolaropoulos, Sotiris S.

Publikováno v: In Steroids 2003 68(7):659-666

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Optimization of the allylic oxidation in the synthesis of 7-keto-Δ⁵-steroidal substrates

Autor: Arsenou, Evaggelia S.¹, Koutsourea, Anna I.¹, Fousteris, Manolis A.¹, Nikolaropoulos, Sotiris S. snikolar@upatras.gr

Publikováno v: Steroids. May2003, Vol. 68 Issue 5, p407. 8p.

The allylic 7-ketone at the steroidal skeleton is crucial for the antileukemic potency of chlorambucil's active metabolite steroidal esters.

Autor: Arsenou ES; Laboratory of Pharmaceutical Chemistry, School of Health Sciences, Department of Pharmacy, University of Patras, Rion-Patras, Greece., Fousteris MA, Koutsourea AI, Papageorgiou A, Karayianni V, Mioglou E, Iakovidou Z, Mourelatos D, Nikolaropoulos SS

Publikováno v: Anti-cancer drugs [Anticancer Drugs] 2004 Nov; Vol. 15 (10), pp. 983-90.